Zobrazeno 1 - 10
of 15
pro vyhledávání: '"D Nigel, Thomas"'
Autor:
Louis Fries, Vivek Shinde, Jeffrey J. Stoddard, D. Nigel Thomas, Eloi Kpamegan, Hanxin Lu, Gale Smith, Somia P. Hickman, Pedro Piedra, Gregory M. Glenn
Publikováno v:
Immunity & Ageing, Vol 14, Iss 1, Pp 1-14 (2017)
Abstract Background A preventative strategy for Respiratory Syncytial Virus (RSV) infection constitutes an under-recognized unmet medical need among older adults. Four formulations of a novel recombinant RSV F nanoparticle vaccine (60 or 90 μg RSV F
Externí odkaz:
https://doaj.org/article/ede5a421c05f45379e58ee05f42f78c7
Autor:
Shabir A, Madhi, Fernando P, Polack, Pedro A, Piedra, Flor M, Munoz, Adrian A, Trenholme, Eric A F, Simões, Geeta K, Swamy, Sapeckshita, Agrawal, Khatija, Ahmed, Allison, August, Abdullah H, Baqui, Anna, Calvert, Janice, Chen, Iksung, Cho, Mark F, Cotton, Clare L, Cutland, Janet A, Englund, Amy, Fix, Bernard, Gonik, Laura, Hammitt, Paul T, Heath, Joanne N, de Jesus, Christine E, Jones, Asma, Khalil, David W, Kimberlin, Romina, Libster, Conrado J, Llapur, Marilla, Lucero, Gonzalo, Pérez Marc, Helen S, Marshall, Masebole S, Masenya, Federico, Martinón-Torres, Jennifer K, Meece, Terry M, Nolan, Ayman, Osman, Kirsten P, Perrett, Joyce S, Plested, Peter C, Richmond, Matthew D, Snape, Julie H, Shakib, Vivek, Shinde, Tanya, Stoney, D Nigel, Thomas, Alan T, Tita, Michael W, Varner, Manu, Vatish, Keith, Vrbicky, Judy, Wen, Khalequ, Zaman, Heather J, Zar, Gregory M, Glenn, Louis F, Fries, Shirley, Wong
Publikováno v:
The New England Journal of Medicine
Summary of study A multi-country randomized, placebo-controlled trial of the safety, immunogenicity and efficacy of respiratory syncytial virus (RSV) F-protein nanoparticle vaccine was undertaken in 4,636 pregnant women and their infants. RSV F-prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044f72715b6fa6e69a67d216cd8eb81e
https://openaccess.sgul.ac.uk/id/eprint/112223/1/nejmoa1908380.pdf
https://openaccess.sgul.ac.uk/id/eprint/112223/1/nejmoa1908380.pdf
Autor:
Michael J. Massare, Gregory M. Glenn, David Flyer, Bin Zhou, Sapeckshita Agrawal, Gale Smith, Vivek Shinde, Michelle Spindler, Louis Fries, Timothy J. Hahn, Iksung Cho, Yukun Wu, D Nigel Thomas, Elizabeth Lindner, Amy Fix, Joyce S Plested
Publikováno v:
New England Journal of Medicine. 378:2346-2348
Improving the Influenza Vaccine Many approaches are being sought to improve the vaccine against influenza virus. In this report, data on the immunogenicity of a nanoparticle vaccine with a baculovi...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89dfb2f99f30da8c69152b55fbba80f8
https://doi.org/10.1056/nejmc1803554
https://doi.org/10.1056/nejmc1803554
Autor:
Amy Fix, D. Nigel Thomas, Joyce S. Plested, Chang-Min Chen, Louis Fries, Gregory M. Glenn, Michelle Spindler, Judy Wen, Iksung Cho
Publikováno v:
Open Forum Infectious Diseases
Background Respiratory syncytial virus (RSV) is the leading viral cause of severe lower respiratory tract infection (LRTI) in infants worldwide, with severe disease occurring in the first months of life. We assessed the efficacy of maternal immunizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a2df0a8bd67fcc1fe7c9bcc583dc6f3
http://europepmc.org/articles/PMC6810251
http://europepmc.org/articles/PMC6810251
Autor:
D. Nigel Thomas, David Flyer, Eloi Kpamegan, Pedro A. Piedra, Dewal Jani, Somia P. Hickman, Gale Smith, Gregory M. Glenn, Hanxin Lu, Louis Fries
Publikováno v:
Journal of Infectious Diseases. 213:411-422
Background Respiratory syncytial virus (RSV) is a leading cause of infant morbidity and mortality. A recombinant RSV fusion protein nanoparticle vaccine (RSV F vaccine) candidate for maternal immunization was tested for safety and immunogenicity in w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878f3322c5abd4eec986efd41ef0500f
https://doi.org/10.1093/infdis/jiv406
https://doi.org/10.1093/infdis/jiv406
Autor:
Louis Fries, Ye Liu, Magnus Sävenhed, Dana Jendrek, Ed Fix, Mats Sjölund, Cynthia N. Oliver, Erica Shane, Kathleen Callahan, Denise Courbron, Katarina Ranlund, Susanna Macmillar, Valerie Moore, Timothy J. Hahn, Jenny M. Reimer, Brian Webb, Kwan-Ho Roh, Gale Smith, Sarathi Boddapati, Christi Mcdowell-Patterson, Ziping Wei, Gregory M. Glenn, Nancy Nidel, Zheng Meng, Celia Baula, James Wong, Victor Gavrilov, Linda Stertman, Karin Lövgren Bengtsson, D. Nigel Thomas, Jingning Li, Stephen Bearman, John Kutney, Camilla Andersson, Jody Lichaa, John P. Higgins, Mike Sowers, Oleg V. Borisov, Larry Ellingsworth, Amy Fix, Win Cheung, Malin Schenerfelt
Publikováno v:
BioProcessing Journal. 14:6-14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6462387b4d59f2b8209c47bf37de763
https://doi.org/10.12665/j141.hahn
https://doi.org/10.12665/j141.hahn
Autor:
Pedro A. Piedra, Nita Patel, Greg Glenn, Joyce S Plested, Louis Fries, Gale Smith, D. Nigel Thomas, Iksung Cho
Publikováno v:
Open Forum Infectious Diseases
Background RSV is the leading cause of infant LRTI and hospitalization worldwide. The greatest burden of severe disease is in term infants Method After dose-finding studies in 1,050 women, we studied vaccine safety and immunogenicity in a Phase 2 tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f70606c713dd7f341c26eecdfae13b7
https://doi.org/10.1093/ofid/ofy229.2193
https://doi.org/10.1093/ofid/ofy229.2193
Autor:
Michelle Spindler, Mingzhu Zhu, Rongman Cai, Nita Patel, Michael J. Massare, D. Nigel Thomas, Nan Wang, Iksung Cho, Gregory M. Glenn, Joyce S. Plested, Haixia Zhou, Shane Cloney-Clark, Gale Smith, Vivek Shinde, Louis Fries, Bin Zhou, Sapeck Agrawal
Publikováno v:
Open Forum Infectious Diseases
Background We developed a recombinant saponin-adjuvanted (Matrix-M1) quadrivalent hemagglutinin nanoparticle influenza vaccine (qNIV; NanoFlu) for older adults to address two impediments to efficacy of current, predominantly egg-derived, seasonal inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc95870b250d6455acf1dae1b8d733a
http://europepmc.org/articles/PMC6809831
http://europepmc.org/articles/PMC6809831
Autor:
Somia P. Hickman, Louis Fries, Gale Smith, Vivek Shinde, Eloi Kpamegan, Pedro A. Piedra, D. Nigel Thomas, Jeffrey J. Stoddard, Gregory M. Glenn, Hanxin Lu
Publikováno v:
Immunity & Ageing : I & A
Immunity & Ageing, Vol 14, Iss 1, Pp 1-14 (2017)
Immunity & Ageing, Vol 14, Iss 1, Pp 1-14 (2017)
Background A preventative strategy for Respiratory Syncytial Virus (RSV) infection constitutes an under-recognized unmet medical need among older adults. Four formulations of a novel recombinant RSV F nanoparticle vaccine (60 or 90 μg RSV F protein,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd667a849390783245954aab72fa8b64
https://pubmed.ncbi.nlm.nih.gov/28413427
https://pubmed.ncbi.nlm.nih.gov/28413427
Autor:
Pedro A. Piedra, Eloi Kpamegan, D. Nigel Thomas, Allison August, Judy Wen, Gregory M. Glenn, Dewal Jani, Hanxin Lu, Louis Fries, Somia P. Hickman
Publikováno v:
Vaccine. 35(30)
Objective Respiratory syncytial virus (RSV) causes significant morbidity and mortality in infants. We are developing an RSV fusion (F) protein nanoparticle vaccine for immunization of third trimester pregnant women to passively protect infants throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492919e19049a854b6ca648f9faccba7
https://pubmed.ncbi.nlm.nih.gov/28579233
https://pubmed.ncbi.nlm.nih.gov/28579233