Zobrazeno 1 - 10
of 402
pro vyhledávání: '"D Neil, Hayes"'
Autor:
Abhinav Thakral, John JW. Lee, Tianzhichao Hou, Katrina Hueniken, Tom Dudding, Mark Gormley, Shama Virani, Andrew Olshan, Brenda Diergaarde, Andrew R. Ness, Tim Waterboer, Karl Smith-Byrne, Paul Brennan, D. Neil Hayes, Eleanor Sanderson, M. Catherine Brown, Sophie Huang, Scott V. Bratman, Anna Spreafico, John De Almeida, Joel C. Davies, Laura Bierut, Gary J. Macfarlane, Pagona Lagiou, Areti Lagiou, Jerry Polesel, Antonio Agudo, Laia Alemany, Wolfgang Ahrens, Claire M. Healy, David I. Conway, Mari Nygard, Cristina Canova, Ivana Holcatova, Lorenzo Richiardi, Ariana Znaor, David P. Goldstein, Rayjean J. Hung, Wei Xu, Geoffrey Liu, Osvaldo Espin-Garcia
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract HPV-positive and HPV-negative head and neck squamous cell carcinoma (HNSCC) are recognized as distinct entities. There remains uncertainty surrounding the causal effects of smoking and alcohol on the development of these two cancer types. He
Externí odkaz:
https://doaj.org/article/d3d477a5f0674925ba9467f628ee8ad5
Autor:
Sarah Asemota, Wendy Effah, Kirsten L. Young, Jeremiah Holt, Linnea Cripe, Suriyan Ponnusamy, Thirumagal Thiyagarajan, Dong-Jin Hwang, Yali He, Keely Mcnamara, Daniel Johnson, Yinan Wang, Brandy Grimes, Yekta Khosrosereshki, T.J. Hollingsworth, Martin D. Fleming, Frances E. Pritchard, Ashley Hendrix, Farhan Khan, Meiyun Fan, Liza Makowski, Zheng Yin, Hironobu Sasano, D. Neil Hayes, Lawrence M. Pfeffer, Duane D. Miller, Ramesh Narayanan
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113461- (2023)
Summary: Triple-negative breast cancer (TNBC) is an aggressive subtype with no targeted therapeutics. The luminal androgen receptor (LAR) subtype constitutes 15% of TNBC and is enriched for androgen receptor (AR) and AR target genes. Here, we show th
Externí odkaz:
https://doaj.org/article/ac241ea52bf347e5b56f2020cc95e398
Autor:
Chieko Michikawa, DDS, PhD, Pedro A. Torres-Saavedra, PhD, Natalie L. Silver, MD, MS, Paul M. Harari, MD, Merrill S. Kies, MD, David I. Rosenthal, MD, Quynh-Thu Le, MD, Richard C. Jordan, DDS, PhD, Dzifa Y. Duose, PhD, Saradhi Mallampati, DVM, PhD, Sanchit Trivedi, MS, Rajyalakshmi Luthra, PhD, Ignacio I. Wistuba, MD, Abdullah A. Osman, PhD, Olivier Lichtarge, MD, PhD, Robert L. Foote, MD, Upendra Parvathaneni, MBBS, D. Neil Hayes, MD, MPH, Curtis R. Pickering, PhD, Jeffrey N. Myers, MD, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 7, Iss 6, Pp 100989- (2022)
Purpose: An evolutionary action scoring algorithm (EAp53) based on phylogenetic sequence variations stratifies patients with head and neck squamous cell carcinoma (HNSCC) bearing TP53 missense mutations as high-risk, associated with poor outcomes, or
Externí odkaz:
https://doaj.org/article/af4a399b5e144a18b46cb1524d746ef0
Autor:
Richa Jain, E. Ritter Sansoni, Jacqueline Angel, John P. Gleysteen, D. Neil Hayes, Adepitan A. Owosho
Publikováno v:
Dentistry Journal, Vol 11, Iss 10, p 229 (2023)
Salivary duct carcinoma with rhabdoid features (SDC-RF) is a rare form of salivary gland neoplasm that was recently described. We report a case of SDC-RF of the parotid gland with loss of E-cadherin and decreased β-catenin expression in a 73-year-ol
Externí odkaz:
https://doaj.org/article/5fb6f35d7ae146578c38c159bbeaed19
Autor:
Siddharth Sheth, Douglas R. Farquhar, Travis P. Schrank, Wesley Stepp, Angela Mazul, Michele Hayward, Nicholas Lenze, Paul Little, Heejoon Jo, M. Ben Major, Bhishamjit S. Chera, Jose P. Zevallos, D. Neil Hayes
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 6, Iss 4, Pp 699-707 (2021)
Abstract Objectives Patients with laryngeal squamous cell carcinoma (LSCC) often fail radiation therapy (RT), when received as monotherapy or in combination with other treatment modalities. Mechanisms for RT failure are poorly understood. We hypothes
Externí odkaz:
https://doaj.org/article/d95dfa5806a34d9a9e399fd03e7d518f
Autor:
Laura M Sipe, Mehdi Chaib, Emily B Korba, Heejoon Jo, Mary Camille Lovely, Brittany R Counts, Ubaid Tanveer, Jeremiah R Holt, Jared C Clements, Neena A John, Deidre Daria, Tony N Marion, Margaret S Bohm, Radhika Sekhri, Ajeeth K Pingili, Bin Teng, James A Carson, D Neil Hayes, Matthew J Davis, Katherine L Cook, Joseph F Pierre, Liza Makowski
Publikováno v:
eLife, Vol 11 (2022)
Bariatric surgery is a sustainable weight loss approach, including vertical sleeve gastrectomy (VSG). Obesity exacerbates tumor growth, while diet-induced weight loss impairs progression. It remains unknown how bariatric surgery-induced weight loss i
Externí odkaz:
https://doaj.org/article/6cdf342dabec4096909e6bcc91bbf1e4
Autor:
Benjamin M. Wahle, Paul Zolkind, Ricardo J. Ramirez, Zachary L. Skidmore, Sydney R. Anderson, Angela Mazul, D. Neil Hayes, Vlad C. Sandulache, Wade L. Thorstad, Douglas Adkins, Obi L. Griffith, Malachi Griffith, Jose P. Zevallos
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104216- (2022)
Summary: Although tobacco use is an independent adverse prognostic feature in HPV(+) oropharyngeal squamous cell carcinoma (OPSCC), the biologic features associated with tobacco use have not been systematically investigated. We characterized genomic
Externí odkaz:
https://doaj.org/article/160f84e48e2245778b702905abcf1e51
Autor:
Hyo Young Choi, Heejoon Jo, Xiaobei Zhao, Katherine A. Hoadley, Scott Newman, Jeremiah Holt, Michele C. Hayward, Michael I. Love, J. S. Marron, D. Neil Hayes
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Many computational tools identify mRNA variations by analyzing the transformed RNA-seq data such as collapsed reads. Here, the authors report a computational method which uses shape changes in the RNA-seq coverage profile to discover changes in mRNA
Externí odkaz:
https://doaj.org/article/27d7ccf793b34947bf85f66b4a4c6778
Autor:
Farhan Khan, Obianuju Mercy Anelo, Qandeel Sadiq, Wendy Effah, Gary Price, Daniel L. Johnson, Suriyan Ponnusamy, Brandy Grimes, Michelle L. Morrison, Jay H. Fowke, D. Neil Hayes, Ramesh Narayanan
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 648 (2023)
Androgen receptor splice variants (AR-SVs) contribute to the aggressive growth of castration-resistant prostate cancer (CRPC). AR-SVs, including AR-V7, are expressed in ~30% of CRPC, but minimally in treatment-naïve primary prostate cancer (PCa). Co
Externí odkaz:
https://doaj.org/article/6bcc6af54d354d46beb55bb163520772
Autor:
Maritza Puray-Chavez, Kyle M. LaPak, Travis P. Schrank, Jennifer L. Elliott, Dhaval P. Bhatt, Megan J. Agajanian, Ria Jasuja, Dana Q. Lawson, Keanu Davis, Paul W. Rothlauf, Zhuoming Liu, Heejoon Jo, Nakyung Lee, Kasyap Tenneti, Jenna E. Eschbach, Christian Shema Mugisha, Emily M. Cousins, Erica W. Cloer, Hung R. Vuong, Laura A. VanBlargan, Adam L. Bailey, Pavlo Gilchuk, James E. Crowe, Jr., Michael S. Diamond, D. Neil Hayes, Sean P.J. Whelan, Amjad Horani, Steven L. Brody, Dennis Goldfarb, M. Ben Major, Sebla B. Kutluay
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109364- (2021)
Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) variants govern transmissibility, responsiveness to vaccination, and disease severity. In a screen for new models of SARS-CoV-2 infection, we identify human H522 lung ade
Externí odkaz:
https://doaj.org/article/fd7ca3003b0d4b6e81dd2ed8d532da99