Zobrazeno 1 - 10
of 78
pro vyhledávání: '"D Neighbors"'
Autor:
Rahul Nachnani, Amy Knehans, Jeffrey D. Neighbors, Paul T. Kocis, Tzuo Lee, Kayla Tegeler, Thomas Trite, Wesley M. Raup-Konsavage, Kent E. Vrana
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundThe recent exponential increase in legalized medical and recreational cannabis, development of medical cannabis programs, and production of unregulated over-the-counter products (e.g., cannabidiol (CBD) oil, and delta-8-tetrahydrocannabinol
Externí odkaz:
https://doaj.org/article/004a2c163e2e4ebe993688ed0a245d48
Autor:
J. S. Weissenrieder, J. D. Weissenkampen, J. L. Reed, M. V. Green, C. Zheng, J. D. Neighbors, D. J. Liu, Raymond J. Hohl
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The schweinfurthin family of natural compounds exhibit a unique and potent differential cytotoxicity against a number of cancer cell lines and may reduce tumor growth in vivo. In some cell lines, such as SF-295 glioma cells, schweinfurthins
Externí odkaz:
https://doaj.org/article/d3aff9adf8a74fb18765cde0bb457c6a
Autor:
Emily J. Koubek, Jillian S. Weissenrieder, Luz E. Ortiz, Nnenna Nwogu, Alexander M. Pham, J. Dylan Weissenkampen, Jessie L. Reed, Jeffrey D. Neighbors, Raymond J. Hohl, Hyun Jin Kwun
Publikováno v:
Viruses, Vol 14, Iss 9, p 1848 (2022)
Merkel cell carcinoma (MCC) is a rare but aggressive form of skin cancer predominantly caused by the human Merkel cell polyomavirus (MCPyV). Treatment for MCC includes excision and radiotherapy of local disease, and chemotherapy or immunotherapy for
Externí odkaz:
https://doaj.org/article/14286ce877a24c61b16ace6b7873e807
Autor:
Jillian S. Weissenrieder, Jessie L. Reed, George‐Lucian Moldovan, Martin T. Johnson, Mohamed Trebak, Jeffrey D. Neighbors, Richard B. Mailman, Raymond J. Hohl
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 3, Pp n/a-n/a (2021)
Abstract Dopamine D2‐like receptor antagonists have been suggested as being potential anticancer therapeutics with specific utility for central nervous system cancers due to their ability to cross the blood‐brain barrier. Despite a plethora of da
Externí odkaz:
https://doaj.org/article/35708c35af8346ed9b57a5f5a2acf42d
Autor:
Kathleen M. Kokolus, Jeremy S. Haley, Emily J. Koubek, Raghavendra Gowda, Saketh S. Dinavahi, Arati Sharma, David F. Claxton, Klaus F. Helm, Joseph J. Drabick, Gavin P. Robertson, Jeffrey D. Neighbors, Raymond J. Hohl, Todd D. Schell
Publikováno v:
OncoImmunology, Vol 8, Iss 2 (2019)
Metastatic melanoma is a significant clinical problem with a 5-year survival rate of only 15–20%. Recent approval of new immunotherapies and targeted inhibitors have provided much needed options for these patients, in some cases promoting dramatic
Externí odkaz:
https://doaj.org/article/5046be52e262417b833f22a08b249b8a
Publikováno v:
Pharmacology. 107(9-10)
Introduction: Multiple myeloma (MM) is a B plasma cell malignancy currently incurable, and novel therapeutics are needed. Evidences regarding the effect of natural compound schweinfurthins suggest that hematological cancers showed growth inhibitory e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::923984efb23b8f1ea25e97fc29db59e5
https://pubmed.ncbi.nlm.nih.gov/35810739
https://pubmed.ncbi.nlm.nih.gov/35810739
Autor:
Jeffrey D. Neighbors, Michelle V. Green, Jillian S. Weissenrieder, Jessie L. Reed, Emily J. Koubek, Raymond J. Hohl, George Lucian Moldovan
Publikováno v:
Pharmacology. 105:19-27
Background: Glioblastoma multiforme (GBM) is a common and lethal cancer of the central nervous system. This cancer is difficult to treat because most anticancer therapeutics do not readily penetrate into the brain due to the tight control at the cere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b1195c54970eefd841c09d173cf4c08
https://doi.org/10.1159/000502562
https://doi.org/10.1159/000502562
Autor:
Veena B. Antony, Qiang Ding, Bradley K. Yoder, Linlin Gu, Chao He, A. Brent Carter, Ranu Surolia, Taylor F. Berryhill, D. Davis, Vidya Sagar Hanumanthu, Stephen Barnes, Jeffrey D. Neighbors, Guo Qiang Cai, Mudit Vaid, Ana Leda F. Longhini, Jennifer L. Larson-Casey, Kurt A. Zimmerman, Landon Wilson, Raymond J. Hohl
Publikováno v:
Journal of Clinical Investigation. 129:4962-4978
Macrophages are important in mounting an innate immune response to injury as well as in repair of injury. Gene expression of Rho proteins is known to be increased in fibrotic models; however, the role of these proteins in idiopathic pulmonary fibrosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f0971d7c9cf28d3adf452429364e22
https://doi.org/10.1172/jci127959
https://doi.org/10.1172/jci127959
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 370:111-126
The dopamine D2 receptor (D2R) family is upregulated in many cancers and tied to stemness. Reduced cancer risk has been correlated with disorders such as schizophrenia and Parkinson's disease, in which dopaminergic drugs are used. D2R antagonists are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d33841e05258af73d9806563c707953
https://doi.org/10.1124/jpet.119.256818
https://doi.org/10.1124/jpet.119.256818
Autor:
Jeffrey D. Neighbors, Raymond J. Hohl, Jillian S. Weissenrieder, George Lucian Moldovan, Mohamed Trebak, Martin Johnson, Jessie L. Reed, Richard B. Mailman
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 3, Pp n/a-n/a (2021)
Dopamine D2‐like receptor antagonists have been suggested as being potential anticancer therapeutics with specific utility for central nervous system cancers due to their ability to cross the blood‐brain barrier. Despite a plethora of data report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc5f0c7430ec5bf9e47ce02cbc837e2
https://doi.org/10.1002/prp2.689
https://doi.org/10.1002/prp2.689