Zobrazeno 1 - 10
of 89
pro vyhledávání: '"D N Mitchell"'
Autor:
J. G. Scadding, D. N. Mitchell
Since the first edition of this book in 1967, interest in sarcoidosis has increased world-wide, leading to increasing numbers of published clinical, epidemiological and laboratory studies, notably in immunology and in the pathogenesis of granulomatou
Autor:
G. J. Gibson, C. K. Connolly, D. N. Mitchell, Robin J Prescott, M. F. Muers, B. D. W. Harrison, W. G. Middleton
Publikováno v:
Thorax. 51:238-247
BACKGROUND: Corticosteroids suppress disease activity in pulmonary sarcoidosis and their use produces symptomatic, radiographic, and functional improvement. There is, however, uncertainty regarding their effects on the overall natural history of the
Autor:
M F, Muers, W G, Middleton, G J, Gibson, R J, Prescott, D N, Mitchell, C K, Connolly, B D, Harrison
Publikováno v:
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG. 14(1)
We used a simple semi-quantitative radiographic scoring system for a controlled prospective study of long term corticosteroids in pulmonary sarcoidosis, conducted by the British Thoracic Society.Radiographic opacities were described in 4 categories:
Publikováno v:
BMJ (Clinical research ed.). 314(7077)
Cardiac arrhythmias and sudden death are likely among patients known to have cardiac lesions from sarcoidosis. Other clinical presentations include conduction defects, congestive heart failure, and a picture suggesting myocardial infarction–but the
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 45(4-5)
Granuloma formation in patients with sarcoidosis may be evoked by the intradermal injection of homogenised sarcoid tissue (the Kveim reaction). Attempts to demonstrate an in vitro counterpart of the reaction have been unsuccessful. The cytokine inter
Publikováno v:
The Lancet. 342:173
Autor:
C S Munro, D N Mitchell
Publikováno v:
Thorax. 42:321-331
Publikováno v:
Journal of Clinical Pathology. 29:203-210
Single lots of a Chase-Siltzbach type I Kveim test material from each of two sarcoid spleens and designated lot 5 of spleen K12 and lot 1 of spleen K13 have been validated alongside a single lot (lot 10) of a 'standard' suspension provided by Dr L. E
Publikováno v:
Thorax. 43:992-997
Interleukin-2 has been reported to enhance the immune response in diseases characterised by defective cell mediated immunity. The effect of exogenous recombinant interleukin-2 was studied on the proliferative and cytotoxic responses of peripheral blo
Publikováno v:
Thorax. 34:57-62
Serum angiotensin I converting enzyme (ACE) and lysozyme have been measured in 23 controls, 115 patients with sarcoidosis, and 64 with other chest diseases. Both enzymes were significantly raised in sarcoidosis. ACE was raised above the normal range