Zobrazeno 1 - 10
of 64
pro vyhledávání: '"D N, Ostrovskiĭ"'
Publikováno v:
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 55(5-6)
The recently discovered nonmevalonate pathway of isoprenoid biosynthesis is a prospective target in screening of new antibiotics. Because of the absence of the pathway in the animal cells, the specific inhibitors of the pathway will be a new class of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d4b97189b495f7a42df1bd84d87b68bb
https://pubmed.ncbi.nlm.nih.gov/21033467
https://pubmed.ncbi.nlm.nih.gov/21033467
Publikováno v:
Prikladnaia biokhimiia i mikrobiologiia. 45(5)
To work out a test system for studying the inhibition of isoprenoid biosynthesis through non-mevalonate pathway, the conversion of 2-(14)C-methylerythritol 2,4-cyclodiphosphate (14C-MEC) into isoprenoids of three bacteria species and into plastids of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fc110162f9127ef5307e11fde2232199
https://pubmed.ncbi.nlm.nih.gov/19845288
https://pubmed.ncbi.nlm.nih.gov/19845288
Publikováno v:
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 52(7-8)
Unlike the mammals, some species of pathogenic microorganisms synthesize isoprenoids by the mevalonate-independent pathway known as the methyl-erythritol phosphate pathway (MEP). The macromolecules of the polyprenyl compounds play an essential role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b6a3b62c992e3cc849ab249719d948f6
https://pubmed.ncbi.nlm.nih.gov/18986018
https://pubmed.ncbi.nlm.nih.gov/18986018
Autor:
S M, Trutko, V A, Shcherbakova, I V, Ivanova, V Ia, Lysanskaia, O V, Arkhipova, N A, Chuvil'skaia, B P, Baskunov, D N, Ostrovskiĭ, V K, Akimenko
Publikováno v:
Mikrobiologiia. 77(3)
Data on the interrelation between the pathways of the carbon source catabolism and isoprenoid biosynthesis in anaerobic and facultatively anaerobic bacteria were obtained. Two pathways of isoprenoid biosynthesis (nonmevalonate and mevalonate) were re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc0cf1da51e84f841f66bb06a67eae82
https://pubmed.ncbi.nlm.nih.gov/18683645
https://pubmed.ncbi.nlm.nih.gov/18683645
Autor:
A V, Goncharenko, Iu V, Ershov, E G, Salina, J, Wiesner, G N, Vostroknutova, A A, Sandanov, A S, Kapel'iants, D N, Ostrovskiĭ
Publikováno v:
Mikrobiologiia. 76(2)
2-C-Methyl-D-erythritol-2,4-cyclopyrophosphate (MEC), an intermediate of the biosynthesis of isoprenoid compounds in bacteria, was found to be capable of exerting a resuscitating effect on resting Mycobacterium smegmatis cells. The introduction of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6fec49f7ac08f3c34e4763b23d8341cf
https://pubmed.ncbi.nlm.nih.gov/17583212
https://pubmed.ncbi.nlm.nih.gov/17583212
Autor:
S M, Trutko, L V, Dorofeeva, L I, Evtushenko, D N, Ostrovskiĭ, M, Hintz, J, Wiesner, H, Jomaa, B P, Baskunov, V K, Akimenko
Publikováno v:
Mikrobiologiia. 74(3)
By using fosmidomycin and mevinolin (inhibitors of the synthesis of isoprenoid pigments), spectrophotometry, and mass spectrometry, the presence of isoprenoid pigments is shown in 71 of the 78 strains under study. All of these strains belong to 11 ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aed1863bc0630ad0a086344d09241fe5
https://pubmed.ncbi.nlm.nih.gov/16119846
https://pubmed.ncbi.nlm.nih.gov/16119846
Autor:
S M, Trutko, L V, Dorofeeva, V A, Shcherbakova, N A, Chuvil'skaia, K S, Laurinavichus, V I, Biniukov, D N, Ostrovskiĭ, M, Hintz, J, Wiesner, H, Jomaa, V K, Akimenko
Publikováno v:
Mikrobiologiia. 74(2)
The effect of fosmidomycin and mevinoline, inhibitors of the nonmevalonate and the mevalonate pathway of isoprenoid biosynthesis, respectively, on the growth of 34 anaerobic and 10 aerobic prokaryotic strains was studied. Fosmidomycin at the concentr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e787f448988468a40d66a485c1dfaed5
https://pubmed.ncbi.nlm.nih.gov/15938394
https://pubmed.ncbi.nlm.nih.gov/15938394
Publikováno v:
Mikrobiologiia. 72(5)
A mercury resistant-soil bacterium P.10.15, identified as a close relative of Pseudomonas veronii, was shown to accumulate a specific compound in the stationary phase of growth. This compound is converted to a long-lived free radical under oxidizing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::956ca60cf8756026823da9863b1cae61
https://pubmed.ncbi.nlm.nih.gov/14679895
https://pubmed.ncbi.nlm.nih.gov/14679895
Autor:
D N, Ostrovskiĭ, G P, Demina, Iu I, Deriabina, A V, Goncharenko, M, Eberl, K B, Shumaev, A S, Shashkov
Publikováno v:
Prikladnaia biokhimiia i mikrobiologiia. 39(5)
Extraction and purification from the biomass of Corynebacterium ammoniagenes of 2-C-methyl-D-erhythritol 2,4-cyclopyrophosphate (MEC) was associated with its spontaneous transformation into a number of derivatives (which was due to pyrophosphate bond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::527662aa059cf68af59f66204d1261fa
https://pubmed.ncbi.nlm.nih.gov/14593871
https://pubmed.ncbi.nlm.nih.gov/14593871
Autor:
V D, Potapov, S F, Biketov, G R, Demina, E I, Lysak, G M, Titareva, I V, Bakhteeva, D N, Ostrovskiĭ
Publikováno v:
Prikladnaia biokhimiia i mikrobiologiia. 37(3)
A strong immunomodulatory effect of 2-C-methyl-D-erythritol-2,4-cyclopyrophosphate (MEC) responsible for the survival of bacteria was shown on isolated macrophages and in experimental infections in mice (typhoid and tularemia). Derivatives of MEC wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::15fa7dd11d1dcb048f6ec0467dbe15ea
https://pubmed.ncbi.nlm.nih.gov/11443893
https://pubmed.ncbi.nlm.nih.gov/11443893