Výsledky vyhledávání - "D N, Garboczi"

HLA-A*0201 complexes with two 10-Mer peptides differing at the P2 anchor residue have distinct refolding kinetics

Autor: P A Robbins, D N Garboczi, J L Strominger

Publikováno v: The Journal of Immunology. 154:703-709

The immune response to viruses partially depends on the biochemical interaction between viral peptides and histocompatibility molecules. In this study, the refolding of recombinant HLA-A*0201 heavy chain and beta 2-microglobulin (beta 2-m) in the pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::77b17490d8d481e1964b4aa664a573c9
https://doi.org/10.4049/jimmunol.154.2.703

Zobrazit plný text záznamu

Structure of a human gammadelta T-cell antigen receptor

Autor: T J, Allison, C C, Winter, J J, Fournié, M, Bonneville, D N, Garboczi

Publikováno v: Nature. 411(6839)

T-cell antigen receptors composed of gamma and delta polypeptide chains (gammadelta TCRs) can directly recognize antigens in the form of intact proteins or non-peptide compounds, unlike alphabeta TCRs, which recognize antigens bound to major histocom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e1f95063cd79cb4383f8d42b887b6df9
https://pubmed.ncbi.nlm.nih.gov/11459064

Zobrazit plný text záznamu

Peptide recognition by two HLA-A2/Tax11-19-specific T cell clones in relationship to their MHC/peptide/TCR crystal structures

Autor: S, Hausmann, W E, Biddison, K J, Smith, Y H, Ding, D N, Garboczi, U, Utz, D C, Wiley, K W, Wucherpfennig

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 162(9)

The crystal structures of two human TCRs specific for a HTLV-I Tax peptide bound to HLA-A2 were recently determined, for the first time allowing a functional comparison of TCRs for which the MHC/peptide/TCR structures are known. Extensive amino acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::85c24aede56d726af9b594ce96b42857
https://pubmed.ncbi.nlm.nih.gov/10228016

Zobrazit plný text záznamu

Assembly, specific binding, and crystallization of a human TCR-alphabeta with an antigenic Tax peptide from human T lymphotropic virus type 1 and the class I MHC molecule HLA-A2

Autor: D N, Garboczi, U, Utz, P, Ghosh, A, Seth, J, Kim, E A, VanTienhoven, W E, Biddison, D C, Wiley

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 157(12)

T lymphocytes use TCR-alphabeta to bind and to recognize complexes of antigenic peptides bound to MHC proteins located at the surface of APCs. We have assembled and crystallized this intercellular complex of TCR/peptide/MHC from soluble human TCR-alp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::76f326956fe416ce5adea8c2b07a9409
https://pubmed.ncbi.nlm.nih.gov/8955188

Zobrazit plný text záznamu

HLA-A*0201 complexes with two 10-Mer peptides differing at the P2 anchor residue have distinct refolding kinetics

Autor: P A, Robbins, D N, Garboczi, J L, Strominger

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 154(2)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::17bac94662c858f418377b4f92a9004d
https://pubmed.ncbi.nlm.nih.gov/7529284

Zobrazit plný text záznamu

Five viral peptide-HLA-A2 co-crystals. Simultaneous space group determination and X-ray data collection

Autor: D N, Garboczi, D R, Madden, D C, Wiley

Publikováno v: Journal of molecular biology. 239(4)

We prepared and crystallized five complexes of the human histocompatibility molecule HLA-A2 with peptides derived from human immunodeficiency virus type 1, human T lymphotropic virus type 1, influenza A virus and hepatitis B virus proteins. Each HLA-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0fb01c1feccee45aa24c666ae83505ff
https://pubmed.ncbi.nlm.nih.gov/7516439

Zobrazit plný text záznamu

Mutational analysis of the consensus nucleotide binding sequences in the rat liver mitochondrial ATP synthase beta-subunit

Autor: P J, Thomas, D N, Garboczi, P L, Pedersen

Publikováno v: The Journal of biological chemistry. 267(28)

The coupling step in the biosynthesis of ATP in biological systems is generally believed to involve an energy-requiring release of ATP bound to the beta-subunit of the ATP synthase complex. A molecular description of the ATP binding site on the beta-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1f9ac55e43b37f0d05db7e281b9405c2
https://pubmed.ncbi.nlm.nih.gov/1400352

Zobrazit plný text záznamu

ATP synthase: structure-function relationships

Autor: P J, Thomas, M, Bianchet, D N, Garboczi, J, Hullihen, L M, Amzel, P L, Pedersen

Publikováno v: Biochimica et biophysica acta. 1101(2)

Recent work has focused on obtaining a better understanding of the three-dimensional structural relationships between the alpha and beta subunits of the F1 moiety and the location of nucleotide binding domains within these subunits. Four types of app

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ce9ec1ea7b114fdb8266df211f4e2aeb
https://pubmed.ncbi.nlm.nih.gov/1385978

Zobrazit plný text záznamu

Mitochondrial F-type ATPases: the glycine-rich loop of the beta-subunit is a pyrophosphate binding domain

Autor: P J, Thomas, D N, Garboczi, P L, Pedersen

Publikováno v: Acta physiologica Scandinavica. Supplementum. 607

The beta-subunit of the mitochondrial ATP synthase complex comprises the bulk, if not all, of the catalytic nucleotide binding site on the enzyme. A region of homologous sequence rich in glycines (G) and containing a basic lysine (K) and a threonine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a6bba3d038fb16b22426a30ee1b15b98
https://pubmed.ncbi.nlm.nih.gov/1333155

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání