Zobrazeno 1 - 7
of 7
pro vyhledávání: '"D N, Burshtyn"'
Autor:
D N Burshtyn, B H Barber
Publikováno v:
The Journal of Immunology. 151:3082-3093
Although it is clear that each component of the class I MHC trimolecular complex (heavy chain, beta 2m, and antigenic peptide) contributes to its formation and stability, the specific interaction governing assembly and disassembly remain to be clarif
Autor:
D N Burshtyn, B H Barber
Publikováno v:
The Journal of Immunology. 151:3070-3081
In an effort to examine the peptide binding properties of purified class I MHC molecules, we have developed a solid phase, radiolabeled peptide binding assay based on the use of H-2Db molecules bound to agarose beads via heavy chain-specific mAb. Usi
Autor:
E O, Long, D F, Barber, D N, Burshtyn, M, Faure, M, Peterson, S, Rajagopalan, V, Renard, M, Sandusky, C C, Stebbins, N, Wagtmann, C, Watzl
Publikováno v:
Immunological reviews. 181
The killer cell immunoglobulin-like receptor (KIR) family includes receptors that bind to HLA class I molecules on target cells and inhibit natural killer (NK)-cell cytotoxicity, and receptors such as KIR3DL7 with no known ligand and function. Inhibi
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(2)
The sequence I/VxYxxL, often referred to as an immunoreceptor tyrosine-based inhibition motif (ITIM), binds to the C-terminal Src homology 2 domain of the tyrosine phosphatase SHP-1. Conserved residues N-terminal of the tyrosine are not ordinarily fo
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 158(1)
The MHC class I-specific inhibitory receptors on human and mouse NK cells have surprisingly different structures. The mouse receptors (Ly-49) are type II transmembrane glycoproteins of the C-type lectin family, whereas the human receptors (killer cel
Autor:
D N, Burshtyn, B H, Barber
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 151(6)
In an effort to examine the peptide binding properties of purified class I MHC molecules, we have developed a solid phase, radiolabeled peptide binding assay based on the use of H-2Db molecules bound to agarose beads via heavy chain-specific mAb. Usi
Autor:
D N, Burshtyn, B H, Barber
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 151(6)
Although it is clear that each component of the class I MHC trimolecular complex (heavy chain, beta 2m, and antigenic peptide) contributes to its formation and stability, the specific interaction governing assembly and disassembly remain to be clarif