Zobrazeno 1 - 10 of 10 pro vyhledávání: '"D N, Benslay"'
2
Anti-inflammatory effects of LY221068 and LY269415
Autor: D. N. Benslay, Richard D. Towner, J. A. Panetta, Peter P.K. Ho, J. K. Shadle
Publikováno v: Agents and Actions. 34:100-102
LY221068, 5-[[3,5-bis(1,1-dimethylethyl)-4-hydroxy phenyl]methylene]-3-(dimethylamino)-4-thiazolidinone, and the monomethylamino analog, LY269415, are anti-oxidants and potent inhibitors of iron dependent lipid peroxidation and 5-lipoxygenase enzyme.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e43b4b61f6033f4be192340a2ad3a90
https://doi.org/10.1007/bf01993249
Zobrazit plný text záznamu
4
Correlation of anti-inflammatory activity with peak tissue rather than peak plasma levels of BF389
Autor: A M, Bendele, K J, Ruterbories, S M, Spaethe, D N, Benslay, T D, Lindstrom, S J, Lee, R W, Naismith
Publikováno v: The Journal of pharmacology and experimental therapeutics. 260(3)
BF389 (Biofor 389) is a potent anti-inflammatory agent in various animal models including adjuvant and type II collagen arthritis in rats. In vitro assays indicate that this compound is a mixed inhibitor of arachidonic acid metabolism. The compound w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::884104e5549a067b6ea969a0a34b6f0d
https://pubmed.ncbi.nlm.nih.gov/1545387
Zobrazit plný text záznamu
5
Anti-inflammatory activity of pergolide, a dopamine receptor agonist
Autor: A M, Bendele, S M, Spaethe, D N, Benslay, H U, Bryant
Publikováno v: The Journal of pharmacology and experimental therapeutics. 259(1)
Pergolide, a dopamine agonist effective in the treatment of Parkinson's disease, has been shown to have anti-inflammatory activity in the carrageenan paw edema assay in rats at p.o. doses greater than or equal to 0.3 mg/kg. Studies were done to inves
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3c22fcd8f7bf7ad513202df7d0f31b57
https://pubmed.ncbi.nlm.nih.gov/1681083
Zobrazit plný text záznamu
6
Development of a rapid screen for detecting and differentiating immunomodulatory vs. anti-inflammatory compounds in rats
Autor: D. N. Benslay, Alison M. Bendele
Publikováno v: Agents and actions. 34(1-2)
Polyarthritis can be induced in rats using a synthetic adjuvant, N,N-dioctyldecyl-N', N-bis(2-hydroxyethyl) propanediamine (LA) suspended in oil. The disease is morphologically indistinguishable from the classic adjuvant arthritis induced by Freund's
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ce6b128a56fcd5f737c8127cc0b5ff
https://pubmed.ncbi.nlm.nih.gov/1793040
Zobrazit plný text záznamu
7
Comparative effects of benoxaprofen and other anti-inflammatory drugs on bone damage in the adjuvant arthritic rat
Autor: R. Nickander, D. N. Benslay
Publikováno v: Agents and actions. 12(3)
Benoxaprofen, a new nonsteroidal anti-inflammatory agent recently marketed as an an antirheumatic drug, has been reported to suppress leucocyte migration into inflammatory sites, possibly by its reported inhibition of leukotriene synthesis. Benoxapro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9853dbdcd1089dda7330cd87fed7b9e0
https://pubmed.ncbi.nlm.nih.gov/7136958
Zobrazit plný text záznamu
8
Radiographic studies of the effect of benoxaprofen on bone damage in the adjuvant arthritic rat
Autor: D N, Benslay, R, Nickander
Publikováno v: European journal of rheumatology and inflammation. 5(2)
The ability of benoxaprofen to suppress bone damage associated with adjuvant-induced arthritis in rats was studied radiographically over a 49-day period. Benoxaprofen was administered orally at a daily dose of 30 mg/kg. Treated and control groups of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6ce83bc7b456c212e835cc585652854d
https://pubmed.ncbi.nlm.nih.gov/7084279
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje