Zobrazeno 1 - 10
of 969
pro vyhledávání: '"D McPherson"'
Autor:
N Parker, T Navsaria, M Lopez, L Marineau, R Maine, K Chu, T Govender, D McPherson, P Navsaria
Publikováno v:
South African Medical Journal, Vol 114, Iss 7 (2024)
Background. Traumatic brain injury (TBI) can result in significant morbidity and mortality if not diagnosed in a timely manner. Brain computed tomography (CT) is the diagnostic gold standard but is of limited availability in most South African public
Externí odkaz:
https://doaj.org/article/f1662b7e6014428fa15c25322891ba29
Autor:
Maura K. Lash, Ned H. Latham, Pui Ying Chan, Mary M.K. Foote, Elizabeth A. Garcia, Matthew F. Silverstein, Marcia Wong, Mark Alexander, Karen A. Alroy, Lovedeep Bajaj, Kuan Chen, James Steele Howard, Lucretia E. Jones, Ellen H. Lee, Julian L. Watkins, Tristan D. McPherson
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 11, Pp 2353-2357 (2023)
We assessed tecovirimat treatment equity for 3,740 mpox patients in New York, New York, USA, during the 2022 mpox emergency; 32.4% received tecovirimat. Treatment rates by race/ethnicity were 38.8% (White), 31.3% (Black/African American), 31.0% (Hisp
Externí odkaz:
https://doaj.org/article/c91893487b4c42f8a8331124102f17cf
Autor:
Sonya R. Kennedy, Maxime Lafond, Kevin J. Haworth, Daniel Suarez Escudero, Dan Ionascu, Brion Frierson, Shaoling Huang, Melvin E. Klegerman, Tao Peng, David D. McPherson, Curtis Genstler, Christy K. Holland
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Ultrasound-enhanced delivery of therapeutic-loaded echogenic liposomes is under development for vascular applications using the EkoSonic Endovascular System. In this study, fibrin-targeted echogenic liposomes loaded with an anti-inflammatory
Externí odkaz:
https://doaj.org/article/47b03a8ce6094d39a359e684fdee0ea0
Autor:
Christina Poh, John D. McPherson, Joseph Tuscano, Qian Li, Arti Parikh-Patel, Christoph F. A. Vogel, Myles Cockburn, Theresa Keegan
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background There is evidence indicating that pesticide exposure is a risk factor for non-Hodgkin lymphoma (NHL) development. However, the association between pesticide exposure and NHL survival is not well-established. Methods Using the Cali
Externí odkaz:
https://doaj.org/article/ec3ef03438e24905b763701143231a12
Autor:
Sadia Ashraf, O. Howard Frazier, Sylvia Carranza, David D. McPherson, Heinrich Taegtmeyer, Romain Harmancey
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 18, p 13709 (2023)
G-protein-coupled receptors (GPCRs) are critical regulators of cardiac physiology and a key therapeutic target for the treatment of heart disease. Ectopic olfactory receptors (ORs) are GPCRs expressed in extra-nasal tissues which have recently emerge
Externí odkaz:
https://doaj.org/article/cceca144700347788fc6f9f37e53aeb5
Autor:
Melvin E. Klegerman, Tao Peng, Shao-Ling Huang, Brion Frierson, Melanie R. Moody, Hyunggun Kim, David D. McPherson
Publikováno v:
Pharmaceutics, Vol 15, Iss 9, p 2288 (2023)
We have conducted a stability study of a complex liposomal pharmaceutical product, Atheroglitatide (AGT), stored at three temperatures, 4, 24, and 37 °C, for up to six months. The six parameters measured were functions of liposomal integrity (size a
Externí odkaz:
https://doaj.org/article/640149126785435a967db9f6ded1c6b9
Autor:
Alex Q. Lee, Hiroaki Konishi, Connie Duong, Sakiko Yoshida, Ryan R. Davis, Jonathan E. Van Dyke, Masami Ijiri, Bridget McLaughlin, Kyoungmi Kim, Yueju Li, Laurel Beckett, Nitin Nitin, John D. McPherson, Clifford G. Tepper, Noriko Satake
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
In leukemia, a distinct subpopulation of cancer-initiating cells called leukemia stem cells (LSCs) is believed to drive population expansion and tumor growth. Failing to eliminate LSCs may result in disease relapse regardless of the amount of non-LSC
Externí odkaz:
https://doaj.org/article/65345325b8c3492586a08bddfb989d5c
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 12844 (2023)
The CRISPR-based genome editing technology, known as clustered regularly interspaced short palindromic repeats (CRISPR), has sparked renewed interest in gene therapy. This interest is accompanied by the development of single-guide RNAs (sgRNAs), whic
Externí odkaz:
https://doaj.org/article/3ae1a92802f34adf97fa7126fff63170
Autor:
Tao Peng, Keith Booher, Melanie R. Moody, Xing Yin, Jaroslaw Aronowski, David D. McPherson, Sean I. Savitz, Hyunggun Kim, Shao-Ling Huang
Publikováno v:
Biomolecules, Vol 13, Iss 8, p 1256 (2023)
Xenon (Xe) has shown great potential as a stroke treatment due to its exceptional ability to protect brain tissue without inducing side effects. We have previously developed Xe-loaded liposomes for the ultrasound-activated delivery of Xe into the cer
Externí odkaz:
https://doaj.org/article/8619f4b6de5f4ab3907598ca424596ee
Publikováno v:
Biomolecules, Vol 13, Iss 5, p 861 (2023)
Atherosclerosis is a complex, multi-stage disease characterized by pathological changes across the vascular wall. Endothelial dysfunction, inflammation, hypoxia, and vascular smooth muscle cell proliferation contribute to its progression. An effectiv
Externí odkaz:
https://doaj.org/article/edf05590591546149cc7724056fc9dc2