Zobrazeno 1 - 10 of 39 pro vyhledávání: '"D McCarey"'
1
Interleukin-6 blockade raises LDL via reduced catabolism rather than via increased synthesis: a cytokine-specific mechanism for cholesterol changes in rheumatoid arthritis
Autor: Jamie Robertson, Muriel J. Caslake, Duncan Porter, Iain B. McInnes, Naveed Sattar, Chris J. Packard, D McCarey
Publikováno v: Annals of the rheumatic diseases. 76(11)
ObjectivesPatients with rheumatoid arthritis (RA) have reduced serum low-density lipoprotein cholesterol (LDL-c), which increases following therapeutic IL-6 blockade. We aimed to define the metabolic pathways underlying these lipid changes.MethodsIn
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6f7ef087a0d2329ab49f6fafd870a8f
https://pubmed.ncbi.nlm.nih.gov/28916714
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4
Psoriatic arthritis: Current topics
Autor: D McCarey, Iain B. McInnes
Publikováno v: Current Rheumatology Reports. 9:442-448
Psoriatic arthritis is a common inflammatory arthropathy that occurs in approximately 25% of psoriasis patients. Due to significant advances in therapeutics--mainly the advent of biologic therapy--the disease has been subject to intense investigation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964dabcdbdd7c8d5137ffac27d2bd975
https://doi.org/10.1007/s11926-007-0072-4
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5
Trial of Atorvastatin in Rheumatoid Arthritis (TARA): double-blind, randomised placebo-controlled trial
Autor: D McCarey, Rajan Madhok, Naveed Sattar, Hilary A Capell, Iain B. McInnes, R Hampson, Ian Ford, Olga Scherbakova
Publikováno v: The Lancet. 363:2015-2021
Rheumatoid arthritis is characterised by inflammatory synovitis, articular destruction, and accelerated atherogenesis. HMG-CoA (3-hydroxy-3-methylglutarylcoenzyme A) reductase inhibitors (statins) mediate clinically significant vascular risk reductio
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbabe7a93c03faeb27f6926e20957f2
https://doi.org/10.1016/s0140-6736(04)16449-0
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6
A Novel Anti-Inflammatory Role for Simvastatin in Inflammatory Arthritis
Autor: Iain B. McInnes, Naveed Sattar, J. Alastair Gracie, Rajan Madhok, Carol Campbell, Bernard P. Leung, D McCarey, Anne Crilly, Foo Y. Liew, Morag Prach, Helen Payne
Publikováno v: ResearcherID
3-Hydroxy-3-methylglutaryl-CoA reductase inhibitors (statins) exert favorable effects on lipoprotein metabolism, but may also possess anti-inflammatory properties. Therefore, we explored the activities of simvastatin, a lipophilic statin, in a Th1-dr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5ffeefc61f151f697236bdf6895150c
https://doi.org/10.4049/jimmunol.170.3.1524
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7
OP0008 Synovial Fibroblast Proliferation Is Enhanced by Microrna-223 Delivery through Monocyte-Derived Microparticles
Autor: Mariola Kurowska-Stolarska, Derek S. Gilchrist, Emma Garcia Melchor, B.E. Morton, D McCarey, Donna McIntyre, Florian M. P. Meier, I.B. McInnes, Ulf Müller-Ladner
Publikováno v: Annals of the Rheumatic Diseases. 75:55.3-56
Background Microparticles (MPs) have been described to function as extracellular vehicles that shuttle microRNAs (miR) from platelets to endothelial cells1 and regulate recipient cell gene expression. Crosstalk of synovial monocytes (MC) with synovia
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e557b5dba65c5a068abe1375260d242a
https://doi.org/10.1136/annrheumdis-2016-eular.4955
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9
EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis
Autor: Sella Aarrestad Provan, D McCarey, Iain B. McInnes, Martin Soubrier, Miguel A. Gonzalez-Gay, Tore K Kvien, Prodromos Sidiropoulos, Mike J L Peters, Michael T. Nurmohamed, Ben A. C. Dijkmans, Anne Grete Semb, Zoltán Szekanecz, Naveed Sattar, H Haentzschel, Paulo Nicola, Deborah P M Symmons, George D. Kitas, Yvo M. Smulders
Publikováno v: Annals of the Rheumatic Diseases, 69(2), 325-331. BMJ Publishing Group
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Peters, M J L, Symmons, D P M, McCarey, D, Dijkmans, B A C, Nicola, P, Kvien, T K, McInnes, I B, Haentzschel, H, Gonzalez-Gay, M A, Provan, S, Semb, A, Sidiropoulos, P, Kitas, G, Smulders, Y M, Soubrier, M, Szekanecz, Z, Sattar, N & Nurmohamed, M T 2010, ' EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis ', Annals of the Rheumatic Diseases, vol. 69, no. 2, pp. 325-331 . https://doi.org/10.1136/ard.2009.113696
http://ard.bmj.com/content/vol69/issue2
Objectives: To develop evidence-based EULAR recommendations for cardiovascular (CV) risk management in patients with rheumatoid arthritis (RA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA). Me
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a95a4d71f68766f6f6e50773e5ddbc5
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10
Comparison of cardiovascular risk in ankylosing spondylitis and rheumatoid arthritis
Autor: D, McCarey, R D, Sturrock
Publikováno v: Clinical and experimental rheumatology. 27(4 Suppl 55)
Cardiovascular co-morbidity is now a recognised complication of chronic inflammation and an elevated acute phase response predisposes to hypertension, stroke and myocardial infarction. Dyslipidaemia is a feature of inflammatory joint diseases and is
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::26cca16486c3db634ae10b06d053e0e1
https://pubmed.ncbi.nlm.nih.gov/19822058
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