Zobrazeno 1 - 10
of 98
pro vyhledávání: '"D Margriet Ouwens"'
Autor:
Maren Carstensen-Kirberg, Karin Röhrig, Corinna Niersmann, D Margriet Ouwens, Bengt F Belgardt, Michael Roden, Christian Herder
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213650 (2019)
Previous studies reported that secreted frizzled-related protein-5 (Sfrp5) decreases beta cell proliferation and increases fasting insulin levels, but studies on direct effects of Sfrp5 on insulin secretion and its underlying mechanisms are missing.
Externí odkaz:
https://doaj.org/article/8af7953a0e5f407fa04fba0d2678b578
Autor:
Nils G Løvsletten, Siril S Bakke, Eili T Kase, D Margriet Ouwens, G Hege Thoresen, Arild C Rustan
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0208048 (2018)
It has previously been shown that pretreatment of differentiated human skeletal muscle cells (myotubes) with eicosapentaenoic acid (EPA) promoted increased uptake of fatty acids and increased triacylglycerol accumulation, compared to pretreatment wit
Externí odkaz:
https://doaj.org/article/5e1bf2d1e97f4c2383cfe53deeccd2b4
Autor:
Maren Carstensen, Claudia Wiza, Karin Röhrig, Pia Fahlbusch, Michael Roden, Christian Herder, D Margriet Ouwens
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85906 (2014)
Secreted frizzled-related protein 5 (Sfrp5) is an adipokine with anti-inflammatory and insulin-sensitizing properties in mice. However, the mechanism of Sfrp5 action, especially in humans, is largely unknown. Therefore, cytokine release and insulin s
Externí odkaz:
https://doaj.org/article/7a6593e4a38f4036945101f7c1e46f7d
Autor:
Sabrina Greulich, Weena J Y Chen, Bujar Maxhera, Luuk J Rijzewijk, Rutger W van der Meer, Jacqueline T Jonker, Heidi Mueller, Daniella Herzfeld de Wiza, Ralf-Ruediger Floerke, Konstantinos Smiris, Hildo J Lamb, Albert de Roos, Jeroen J Bax, Johannes A Romijn, Jan W A Smit, Payam Akhyari, Artur Lichtenberg, Juergen Eckel, Michaela Diamant, D Margriet Ouwens
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59697 (2013)
CONTEXT: Adipokines are linked to the development of cardiovascular dysfunction in type 2 diabetes (DM2). In DM2-patients, circulating levels of omentin-1, an adipokine preferentially expressed in epicardial adipose tissue, are decreased. This study
Externí odkaz:
https://doaj.org/article/d200033f4e2e4d5b96da194a0a3e2934
Autor:
Margot Berings, Charline Wehlou, An Verrijken, Ellen Deschepper, Ilse Mertens, Jean-Marc Kaufman, Luc F Van Gaal, D Margriet Ouwens, Johannes B Ruige
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45145 (2012)
CONTEXT: Lipotoxicity is a risk factor for developing obesity-related metabolic complications, including non-alcoholic fatty liver disease, type 2 diabetes (DM2), cardiovascular disease and stroke. Yet, the mechanisms underlying the development of li
Externí odkaz:
https://doaj.org/article/d56facb12d0448999eac3ec74622373f
Autor:
Mark M. Smits, Jens J. Holst, D. Margriet Ouwens, Daniël H. van Raalte, Bolette Hartmann, Lennart Tonneijck, Marcel H.A. Muskiet, A.H. Jan Danser, Mark H.H. Kramer, Jaap A. Joles
Publikováno v:
Diabetes, Obesity and Metabolism, 24(1), 115-124. Wiley-Blackwell Publishing Ltd
Muskiet, M H A, Tonneijck, L, Smits, M M, Kramer, M H H, Ouwens, D M, Hartmann, B, Holst, J J, Danser, A H J, Joles, J A & van Raalte, D H 2022, ' Postprandial renal haemodynamic effects of the dipeptidyl peptidase-4 inhibitor linagliptin versus the sulphonylurea glimepiride in adults with type 2 diabetes (RENALIS) : A predefined substudy of a randomized, double-blind trial ', Diabetes, Obesity and Metabolism, vol. 24, no. 1, pp. 115-124 . https://doi.org/10.1111/dom.14557
Diabetes, Obesity and Metabolism, 24(1), 115-124. Wiley-Blackwell
Muskiet, M H A, Tonneijck, L, Smits, M M, Kramer, M H H, Ouwens, D M, Hartmann, B, Holst, J J, Danser, A H J, Joles, J A & van Raalte, D H 2022, ' Postprandial renal haemodynamic effects of the dipeptidyl peptidase-4 inhibitor linagliptin versus the sulphonylurea glimepiride in adults with type 2 diabetes (RENALIS) : A predefined substudy of a randomized, double-blind trial ', Diabetes, Obesity and Metabolism, vol. 24, no. 1, pp. 115-124 . https://doi.org/10.1111/dom.14557
Diabetes, Obesity and Metabolism, 24(1), 115-124. Wiley-Blackwell
Aim: To determine the effect of the dipeptidyl peptidase-4 inhibitor linagliptin on postprandial glomerular hyperfiltration compared with the sulphonylurea glimepiride in adults with type 2 diabetes (T2D). Materials and Methods: In this predefined su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::534caa9602f0c50db8374da17849d33f
http://www.scopus.com/inward/record.url?scp=85116479294&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85116479294&partnerID=8YFLogxK
Autor:
Lennart Tonneijck, D. Margriet Ouwens, Mark M. Smits, Jordan Kraaijenhof, Mark H.H. Kramer, Marcel H.A. Muskiet, Daniël H. van Raalte
Publikováno v:
Kraaijenhof, J, Muskiet, M H A, Tonneijck, L, Ouwens, D M, Kramer, M H H, van Raalte, D H & Smits, M M 2020, ' Effects of dipeptidyl peptidase-4 inhibitor linagliptin versus sulphonylurea glimepiride on systemic haemodynamics in overweight patients with type 2 diabetes : A secondary analysis of an 8-week, randomized, controlled, double-blind trial ', Diabetes, Obesity and Metabolism, vol. 22, no. 10, pp. 1847-1856 . https://doi.org/10.1111/dom.14107
Diabetes, Obesity and Metabolism, 22(10), 1847-1856. Wiley-Blackwell
Diabetes, Obesity & Metabolism
Diabetes, Obesity and Metabolism, 22(10), 1847-1856. Wiley-Blackwell
Diabetes, Obesity & Metabolism
Aim To determine the glucose‐independent effect of the dipeptidyl peptidase‐4 (DPP‐4) inhibitor linagliptin versus the sulphonylurea glimepiride on systemic haemodynamics in the fasting and postprandial state in patients with type 2 diabetes (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aadaca70671e98a7f6232eaeaae5f62
http://www.scopus.com/inward/record.url?scp=85087213101&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85087213101&partnerID=8YFLogxK
Autor:
Sarah Görigk, D. Margriet Ouwens, Tanja Kuhn, Delsi Altenhofen, Christian Binsch, Mareike Damen, Jenny Minh-An Khuong, Katharina Kaiser, Birgit Knebel, Heike Vogel, Annette Schürmann, Alexandra Chadt, Hadi Al-Hasani
Publikováno v:
Biochimica et biophysica acta. Molecular and cell biology of lipids. 1867(6)
Changes in intracellular CoA levels are known to contribute to the development of non-alcoholic fatty liver disease (NAFLD) in type 2 diabetes (T2D) in human and rodents. However, the underlying genetic basis is still poorly understood. Due to their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d746fea2aa63ad6642b15f6a2a3c0925
https://pubmed.ncbi.nlm.nih.gov/35367353
https://pubmed.ncbi.nlm.nih.gov/35367353
Autor:
Jessica I. Selig, H. Viviana Krug, Caroline Küppers, D. Margriet Ouwens, Felix A. Kraft, Elena Adler, Sebastian J. Bauer, Artur Lichtenberg, Payam Akhyari, Mareike Barth
Publikováno v:
Frontiers in Cardiovascular Medicine 9, [1]-17 (2022). doi:10.3389/fcvm.2022.942430
Frontiers in Cardiovascular Medicine 9, [1]-17 (2022). doi:10.3389/fcvm.2022.942430
Published by Frontiers Media, Lausanne
Published by Frontiers Media, Lausanne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31456fe2c50c7c3aa3020bc6180a14d0
Autor:
D. Margriet Ouwens, Lennart Tonneijck, A.H. Jan Danser, Bolette Hartmann, Mark H.H. Kramer, Jens J. Holst, Mark M. Smits, Daniël H. van Raalte, Jaap A. Joles, Marcel H.A. Muskiet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e1a1b852eb5196cd393b824e65c2beb
https://doi.org/10.1111/dom.14557/v2/response1
https://doi.org/10.1111/dom.14557/v2/response1