Zobrazeno 1 - 10
of 13
pro vyhledávání: '"D M. Simond"'
Autor:
Jenny E. Gunton, Anita T. Patel, Rebecca A. Stokes, D M. Simond, Heather Burns, Philip J. O'Connell, Wayne J. Hawthorne
Publikováno v:
Diabetologia
Aims/hypothesis Xenotransplantation has great potential to provide beta cell replacement and thereby provide a cure for large numbers of people with type 1 diabetes. Crucial to the success of xenotransplantation is establishment of the most viable si
Autor:
Wayne J. Hawthorne, Jane Burgess, Stacey N. Walters, Rebecca A. Stokes, D M. Simond, Philip J. O'Connell, Anita T. Patel
Publikováno v:
Xenotransplantation. 18:390-399
Hawthorne WJ, Simond DM, Stokes R, Patel AT, Walters S, Burgess J, O’Connell PJ. Pre-clinical model of composite foetal pig pancreas fragment/renal xenotransplantation to treat renal failure and diabetes. Xenotransplantation 2011; 18: 390–399. ©
Autor:
Simon Y. W. Ho, Ettore Randi, Stewart Lowden, Chris Moran, Wee Tek Tay, Daniel J. White, Hans Klingel, Chandramaya Siska Damayanti, C. J. Palgrave, Jaime Gongora, C.J. Rodrigues-Zarate, D M. Simond, Kari L. Allen, Greger Larson, R.E. Cuddahee, F.F. do Nascimento
Publikováno v:
Zoologica Scripta. 40:327-335
Although African suids have been of scientific interest for over two centuries, their origin, evolution, phylogeography and phylogenetic relationships remain contentious. There has been a long-running debate concerning the evolution of pigs and hogs
Autor:
Shounan Yi, Z. Ye, B. Ye, Wei Wang, D M. Simond, X.W. Xing, Wayne J. Hawthorne, Q. Dong, Q.J. Tong
Publikováno v:
Transplantation Proceedings. 41:4389-4393
Porcine endogenous retrovirus (PERV) varies between pig breeds. Screening and analysis of PERV in putative pig breeds may provide basic parameters to evaluate the biological safety of xenotransplantation from pigs to humans. In this study, PERV was i
Publikováno v:
Scopus-Elsevier
The xenotransplantation of pig organs and cells can be related with a risk of transmission of infectious diseases to human. Previous findings indicate that the regulatory region of PERV for retroviral transcription, replication and integration into t
Characterization of the swine major histocompatibility complex alleles at eight loci in Westran pigs
Autor:
Wayne J. Hawthorne, Jun Heon Lee, Chris Moran, Stacey N. Walters, Anita T. Patel, Douglas M. Smith, P. J. O'connell, D M. Simond
Publikováno v:
Xenotransplantation. 12:303-307
Background: Pigs are an important large animal model for transplantation and a potential source of xenografts. Swine leukocyte antigen (SLA) molecules are strong mediators of alloreactive and xenoreactive immune responses. We have characterized the S
Autor:
Wayne J. Hawthorne, Jingjing Wu, Yiling Fu, Shounan Yi, Elvira Jimenez, D M. Simond, Philip J. O'Connell
Publikováno v:
Transplantation. 86(6)
Background Macrophages are important effector cells in T cell-mediated xenograft rejection. The aim of this study was to determine whether CD4+CD25+ regulatory T cells (Tregs) were capable of suppressing macrophage activation in vitro. Methods Porcin
Autor:
Jeremy R. Chapman, Lyanne Weston, Chris Moran, D M. Simond, Richard D. M. Allen, Anita T. Patel, Philip J. O'Connell, Rebecca A. Stokes, Jane Burgess, Stacey N. Walters, Wayne J. Hawthorne, Yizhou Chen
Publikováno v:
Xenotransplantation. 12(4)
Background: The Westran pig has been purposely inbred for use in xenotransplantation. The herd originated in the wild from a limited gene pool and has been inbred by repeated full-sib matings for nine generations. Methods: The aim of this study was t
Publikováno v:
Transplantation. 86:555
Autor:
Jennifer M. O’Hara, Andrew M. Lew, Anita T. Patel, Evelyn J Salvaris, K Moyle, D M. Simond, Emmanuel J. Favaloro, A dʼApice, Sarah L. Londrigan, Simon C. Robson, P. OʼConnell, Peter J. Cowan, Wayne J. Hawthorne, K Waite, N. Fisicaro, Mark B. Nottle
Publikováno v:
Transplantation. 86:26