Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types

Autor: K. Yu, B. Chen, D. Aran, J. Charalel, C. Yau, D. M. Wolf, L. J. van ‘t Veer, A. J. Butte, T. Goldstein, M. Sirota

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)

Cell lines are used ubiquitously in cancer research but how well they represent the tumor type they were derived from is variable. Here, the authors compare transcriptomic profiles of 22 tumor types and cell lines and propose a new comprehensive cell

Externí odkaz: https://doaj.org/article/2bd5c7c643b4495ab1808a6fe07e85de

Lac Repressor Inducible Gene Expression in Human Breast Cancer Cells In Vitro and in a Xenograft Tumor

Autor: Adrian V. Lee, Sean E. McGuire, C. N. Weng, D. M. Wolf, Douglas Yee

Publikováno v: BioTechniques. 23:1062-1068

We have studied the lac repressor (lacR) system in two breast cancer cell lines, MCF-7 and MDA-MB-231, in vitro and in vivo. Breast cancer cell lines were stably transfected with lacR and tested for inducibility by transient transfection with a lac o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5e1c1c3fd771422ecde8423fbc3d59e4
https://doi.org/10.2144/97236st02

Investigation of the Mechanism of Tamoxifen-Stimulated Breast Tumor Growth With Nonisomerizable Analogues of Tamoxifen and Metabolites

Autor: C J Parker, Susan M. Langan-Fahey, D M Wolf, R McCague, Virgil Craig Jordan

Publikováno v: JNCI Journal of the National Cancer Institute. 85:806-812

Background The nonsteroidal anti-estrogen tamoxifen (TAM) is the front-line endocrine treatment for breast cancer, but disease recurrence is common. Treatment failure may occur because tumors become insensitive to TAM. Alternatively, resistance may o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::493ea7e6878893a5054be765084f9b80
https://doi.org/10.1093/jnci/85.10.806

Clinical efficacy, safety and pharmacokinetic properties of the factor VIII concentrate Haemoctin SDH in previously treated patients with severe haemophilia A

Autor: Stanislaw Lopaciuk, Anna Klukowska, R. Rokicka-Milewska, Pawel Laguna, Jerzy Windyga, W. G. Struff, R. Kotitschke, D. M. Wolf, A. B. Skotnicki

Publikováno v: Haemophilia : the official journal of the World Federation of Hemophilia. 10(5)

Summary. Clinical efficacy, safety and pharmacokinetic properties of the high-purity double-virus inactivated plasma-derived factor VIII concentrate Haemoctin® SDH (pdFVIII) were evaluated in three prospective open-label uncontrolled studies in prev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a1872f9e18c83e8998c444194cc66cc
https://pubmed.ncbi.nlm.nih.gov/15357768

Palmer Deep composite depth scales for Leg 178 Sites 1098 and 1099. In Antarctic glacial history and sea level change

Autor: ACTON, G.D., BORTON C.J. SHIPBOARD SCIENTIFIC PARTY( BARKER, P.F. CAMERLENGHI, A. BRACHFELD, S.A., COWAN, E, A., DANIELS, J., DOMACK, E.W., ESCUTIA, C., EVANS, A.J., EYLES, N., GUYODO, Y. J. B., IORIO, M., IWAI, M., KYTE, F. T., LAUER, C., MALDONADO, A., MOERZ, T., OSTERMAN, L.,E., PUDSEY, C., J., SCHUFFERT, J. D., SJUNNESKOG, C., M., VIGAR, K. L., WEINHEIMER, A. L., WILLIAMS, T., WINTER, D. M., WOLF-WELLING, T. C. W.)

Publikováno v: pp. 1–35, 2001
info:cnr-pdr/source/autori:ACTON, G.D., BORTON C.J. SHIPBOARD SCIENTIFIC PARTY( BARKER, P.F. CAMERLENGHI, A. BRACHFELD, S.A., COWAN, E, A., DANIELS, J., DOMACK, E.W., ESCUTIA, C., EVANS, A.J., EYLES, N., GUYODO, Y. J. B., IORIO, M., IWAI, M., KYTE, F. T., LAUER, C., MALDONADO, A., MOERZ, T., OSTERMAN, L.,E. ; PUDSEY, C., J., SCHUFFERT, J. D., SJUNNESKOG, C., M., VIGAR, K. L., WEINHEIMER, A. L., WILLIAMS, T., WINTER, D. M., WOLF-WELLING, T. C. W.)/titolo:Palmer Deep composite depth scales for Leg 178 Sites 1098 and 1099. In Antarctic glacial history and sea level change./titolo_volume:/curatori_volume:/editore:/anno:2001

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::e9ea9dbeec3d6f57ce45535e1e21f326
http://www.cnr.it/prodotto/i/213943