Zobrazeno 1 - 10
of 13
pro vyhledávání: '"D M Willerford"'
Publikováno v:
The Journal of Immunology. 158:3738-3745
IL-2 was initially defined as a T lymphocyte growth factor, but recent studies have provided evidence that it may also play a role in regulating T cell differentiation, apoptosis, and tolerance. To examine the contribution of IL-2 to these processes,
Publikováno v:
American journal of hematology. 64(3)
Chronic neutrophilic leukemia (CNL) is a rare myeloproliferative disorder in which recurrent abnormalities of chromosome 20 have been reported. We report the case of a 76-year-old woman with CNL with partial deletion of the long arm of chromosome 20
Publikováno v:
Blood. 94(12)
Publikováno v:
Blood. 93(9)
The hallmark of T- and B-lymphocyte development is the rearrangement of variable (V), diversity (D), and joining (J) segments of T-cell receptor (TCR) and immunoglobulin (Ig) genes to generate a diverse repertoire of antigen receptor specificities in
Autor:
B H, Nelson, D M, Willerford
Publikováno v:
Advances in immunology. 70
Studies of the biology of the IL-2 receptor have played a major part in establishing several of the fundamental principles that govern our current understanding of immunology. Chief among these is the contribution made by lymphokines to regulation of
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(2)
TCR stimulation of T lymphocytes that are activated and cycling in the presence of IL-2 leads to programmed cell death. We now show that this effect is at least partly attributable to the ability of IL-2 to dramatically increase the expression of mRN
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 158(8)
IL-2 was initially defined as a T lymphocyte growth factor, but recent studies have provided evidence that it may also play a role in regulating T cell differentiation, apoptosis, and tolerance. To examine the contribution of IL-2 to these processes,
Publikováno v:
The Journal of infusional chemotherapy. 6(1)
The rapid rescue of hematopoiesis following transplantation of peripheral blood stem cells (PBSC) has facilitated expanded application of high-dose chemotherapy regimens for several malignancies. A variety of regimens have been described to enhance t
Autor:
D B, Clemetson, G B, Moss, D M, Willerford, M, Hensel, W, Emonyi, K K, Holmes, F, Plummer, J, Ndinya-Achola, P L, Roberts, S, Hillier
Publikováno v:
JAMA. 269(22)
Factors that influence heterosexual transmission of the human immunodeficiency virus (HIV), including sexually transmitted diseases, contraceptive practices, sexual practices, HIV-related immunosuppression, and presence of cervical ectopy and the pen
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 144(10)
HIV and the related simian immunodeficiency virus (SIV), which causes AIDS in macaques, infect only a small percentage of CD4+ lymphocytes at any point during the disease. We have identified three distinct cellular phenotypes within the CD4+ subpopul