Zobrazeno 1 - 10
of 56
pro vyhledávání: '"D M Willerford"'
Publikováno v:
The Journal of Immunology. 158:3738-3745
IL-2 was initially defined as a T lymphocyte growth factor, but recent studies have provided evidence that it may also play a role in regulating T cell differentiation, apoptosis, and tolerance. To examine the contribution of IL-2 to these processes,
Publikováno v:
American journal of hematology. 64(3)
Chronic neutrophilic leukemia (CNL) is a rare myeloproliferative disorder in which recurrent abnormalities of chromosome 20 have been reported. We report the case of a 76-year-old woman with CNL with partial deletion of the long arm of chromosome 20
Publikováno v:
Blood. 94(12)
Publikováno v:
Blood. 93(9)
The hallmark of T- and B-lymphocyte development is the rearrangement of variable (V), diversity (D), and joining (J) segments of T-cell receptor (TCR) and immunoglobulin (Ig) genes to generate a diverse repertoire of antigen receptor specificities in
Autor:
B H, Nelson, D M, Willerford
Publikováno v:
Advances in immunology. 70
Studies of the biology of the IL-2 receptor have played a major part in establishing several of the fundamental principles that govern our current understanding of immunology. Chief among these is the contribution made by lymphokines to regulation of
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(2)
TCR stimulation of T lymphocytes that are activated and cycling in the presence of IL-2 leads to programmed cell death. We now show that this effect is at least partly attributable to the ability of IL-2 to dramatically increase the expression of mRN
Publikováno v:
The Journal of infusional chemotherapy. 6(1)
The rapid rescue of hematopoiesis following transplantation of peripheral blood stem cells (PBSC) has facilitated expanded application of high-dose chemotherapy regimens for several malignancies. A variety of regimens have been described to enhance t
Autor:
D B, Clemetson, G B, Moss, D M, Willerford, M, Hensel, W, Emonyi, K K, Holmes, F, Plummer, J, Ndinya-Achola, P L, Roberts, S, Hillier
Publikováno v:
JAMA. 269(22)
Factors that influence heterosexual transmission of the human immunodeficiency virus (HIV), including sexually transmitted diseases, contraceptive practices, sexual practices, HIV-related immunosuppression, and presence of cervical ectopy and the pen
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 144(10)
HIV and the related simian immunodeficiency virus (SIV), which causes AIDS in macaques, infect only a small percentage of CD4+ lymphocytes at any point during the disease. We have identified three distinct cellular phenotypes within the CD4+ subpopul
Publikováno v:
The Journal of Immunology. 142:3416-3422
Glycoproteins of 90 to 95 kD Mr are involved in adhesion to high endothelium and migration into secondary lymphoid tissues in several species. Recent evidence indicates that in primates, one type of these molecules may be subsumed under the CD44 grou