Zobrazeno 1 - 10
of 25
pro vyhledávání: '"D M Livingston"'
Publikováno v:
Molecular and Cellular Biology. 13:3975-3983
The transcription factor E2F activates the expression of multiple genes involved in cell proliferation, such as c-myc and the dihydrofolate reductase gene. Regulation of E2F involves its interactions with other cellular proteins, including the retino
Publikováno v:
Molecular and Cellular Biology. 13:367-372
The retinoblastoma gene product (RB) undergoes cell cycle-dependent phosphorylation and dephosphorylation. Pulse-chase experiments revealed that the change in RB gel electrophoretic migration which occurs near mitosis is due to enzymatic dephosphoryl
Publikováno v:
Genesdevelopment. 14(3)
Mice with monoallelic inactivation of the CBP gene develop highly penetrant, multilineage defects in hematopoietic differentiation and, with advancing age, an increased incidence of hematologic malignancies. The latter are characterized, at least in
Publikováno v:
Cancer research. 59
The two major hereditary breast cancer susceptibility genes, BRCA1 and BRCA2, are associated with early-onset breast and/or ovarian cancer and encode products that each interact with the product of the eukaryotic RecA homologue, hRad51. We have recen
Autor:
M M, Nguyen, D M, Livingston
Publikováno v:
Yeast (Chichester, England). 13(11)
We have cloned a suppressor of a temperature-sensitive rad52 allele and found it to be a mutation in PUP1, a gene encoding a protease subunit of the 20s proteasome. This identity prompted us to examine the interrelationship among PUP1, RAD52, SRS2 an
Autor:
D M, Livingston
Publikováno v:
JAMA. 277(18)
Publikováno v:
Genomics. 30(2)
Publikováno v:
The Journal of biological chemistry. 267(2)
The elongation factor 2 (EF-2) genes of the yeast Saccharomyces cerevisiae have been cloned and characterized with the ultimate goal of gaining a better understanding of the mechanism and control of protein synthesis. Two genes (EFT1 and EFT2) were i
Autor:
D M, Livingston
Publikováno v:
Cancer surveys. 12
Autor:
D. M. Livingston
Publikováno v:
JAMA: The Journal of the American Medical Association. 277:1476-1477