[Detection and treatment of familial hypercholesterolaemia; the earlier, the better?]

Autor: D M, Kusters, B A, Hutten, A, Wiegman, M C, Cornel

Publikováno v: Nederlands tijdschrift voor geneeskunde. 164

A recent Dutch study in patients with familial hypercholesterolaemia (FH), suggests that long-term statin treatment initiated at childhood reduces the risk for cardiovascular events in adulthood. None of the patients developed rhabdomyolysis or other

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8ee877b5dcb0dcc1fdb2b1ae64074c05
https://pubmed.ncbi.nlm.nih.gov/32749800

Homozygous autosomal dominant hypercholesterolaemia in the Netherlands: prevalence, genotype-phenotype relationship, and clinical outcome

Autor: Joost Besseling, G. Kees Hovingh, Barbara Sjouke, Anton F. H. Stalenhoef, Albert Wiegman, Sigrid W. Fouchier, Joep C. Defesche, John J.P. Kastelein, Jeanine E. Roeters van Lennep, D. M. Kusters, Jacqueline de Graaf, Eric J.G. Sijbrands, Iris Kindt

Publikováno v: European Heart Journal, 36, 560-5
European Heart Journal, 36, 9, pp. 560-5
European Heart Journal, 36(9), 560-565. Oxford University Press
European heart journal, 36(9), 560-565. Oxford University Press

Item does not contain fulltext AIMS: Homozygous autosomal dominant hypercholesterolaemia (hoADH), an orphan disease caused by mutations in low-density lipoprotein receptor (LDLR), apolipoprotein B (APOB), or proprotein convertase subtilisin-kexin typ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8848db858fac15b39f105ddfe337f0d5
https://hdl.handle.net/2066/152999

Cardiovascular Risk in Obese Children and Hypercholesterolemic Children; a Wake-Up Call for Paediatricians?

Autor: Bart Koot, Barbara A. Hutten, Saskia Bouma, D. M. Kusters, Bert Wiegman, John J.P. Kastelein

Publikováno v: Atherosclerosis Supplements. 32:32

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::112f5e8f0979c0fe223c8ec7537512a0
https://doi.org/10.1016/j.atherosclerosissup.2018.04.090

Carotid Intima-Media Thickness in Children With Familial Hypercholesterolemia

Autor: Albert Wiegman, Barbara A. Hutten, D. M. Kusters, John J.P. Kastelein

Publikováno v: Circulation research, 114(2), 307-310. Lippincott Williams and Wilkins

Rationale: Familial hypercholesterolemia (FH) predisposes patients to premature cardiovascular disease, with the process of atherosclerosis initiated in early childhood. Objective: As part of an ongoing trial to assess the efficacy and safety of rosu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133f852897b6852f782d889d2bee88f0
https://pure.amc.nl/en/publications/carotid-intimamedia-thickness-in-children-with-familial-hypercholesterolemia(269c9177-c491-4678-895c-79837421130b).html

Founder mutations in the Netherlands: geographical distribution of the most prevalent mutations in the low-density lipoprotein receptor and apolipoprotein B genes

Autor: M. N. Vissers, Joep C. Defesche, Barbara A. Hutten, Iris Kindt, R. Huijgen, John J. P. Kastelein, D. M. Kusters

Publikováno v: Netherlands Heart Journal
Netherlands heart journal, 19(4), 175-182. Bohn Stafleu van Loghum

BACKGROUND: In the Netherlands, a screening programme was set up in 1994 in order to identify all patients with familial hypercholesterolaemia (FH). After 15 years of screening, we evaluated the geographical distribution, possible founder effects and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09ba91e90f6a5fd9ccf2f497f5f59cc
https://pubmed.ncbi.nlm.nih.gov/21475731