Zobrazeno 1 - 10
of 22
pro vyhledávání: '"D M Kornhauser"'
Autor:
S Kuwahara, L J Nerhood, D M Kornhauser, J Gambertoglio, Brent G. Petty, R Hafner, Patricia Barditch-Crovo, Paul S. Lietman
Publikováno v:
Antiviral Research. 38:209-212
For systemic use, the anti-cytomegalovirus (CMV) agent foscarnet must be given intravenously because oral administration results in unmeasurable or barely measurable plasma levels. At low pH, foscarnet decomposes via an acid-catalyzed decarboxylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e9b6c4633d3cdb199a3bcb727f7ca7
https://doi.org/10.1016/s0166-3542(98)00024-2
https://doi.org/10.1016/s0166-3542(98)00024-2
Publikováno v:
Journal of clinical pharmacy and therapeutics. 37(5)
The antipsychotic, aripiprazole, plus lithium or valproate demonstrates rapid and significant improvement in manic symptoms that is sustained over the long term. A previous report showed that therapeutic doses of either lithium or valproate had no cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c9ecdee8293dddf39b8ec38fedfb011a
https://pubmed.ncbi.nlm.nih.gov/22943745
https://pubmed.ncbi.nlm.nih.gov/22943745
Publikováno v:
Journal of Clinical Pharmacy and Therapeutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8b927ab7716d6040d5b4e6d62b778e2
https://doi.org/10.1111/j.1365-2710.2012.1331.x
https://doi.org/10.1111/j.1365-2710.2012.1331.x
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 577:299-304
Thermospray liquid chromatography-mass spectrometry was investigated as a method for quantification of 2',3'-dideoxycytidine (DDC) from human plasma. A stable isotope analog of DDC ([15N2,2H2]DDC) was used as an internal standard. Selected ion monito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f99d61264b4800f4adbf5829d7229895
https://doi.org/10.1016/0378-4347(92)80251-k
https://doi.org/10.1016/0378-4347(92)80251-k
Autor:
Craig W. Hendrix, Richard E. Chaisson, Patricia Barditch-Crovo, Brent G. Petty, K J Lorentsen, Charles Flexner, L J Nerhood, H Farzadegan, D M Kornhauser, K M Bell
Publikováno v:
Antimicrobial Agents and Chemotherapy. 35:2544-2550
Polysulfated polysaccharides are attractive candidates for antiviral drug development because of their potent in vitro activities against human immunodeficiency virus (HIV), herpesviruses, and other enveloped viruses. To determine the potential anti-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5c3948134cfcc3c6ba5be61a5c3b968
https://doi.org/10.1128/aac.35.12.2544
https://doi.org/10.1128/aac.35.12.2544
Publikováno v:
Antimicrobial Agents and Chemotherapy. 34:1459-1461
Atypical vancomycin pharmacokinetics were observed in an immunoglobulin A myeloma patient. Drug concentrations in serum were extremely elevated, the elimination half-life was prolonged despite normal renal function, and the vancomycin therapy was ine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee2443f9c92b7c7bba6d8be680b5ca90
https://doi.org/10.1128/aac.34.7.1459
https://doi.org/10.1128/aac.34.7.1459
Autor:
Y. Ru, G. Emmett, Qi Han, Edward R. Holler, T. R. Sharpe, M. M. Rayner, Hodge Carl Nicholas, Renhua Li, Dean L. Winslow, Robert J. McHugh, P. E. Aldrich, George Vincent Delucca, P. N. Confalone, Jay A. Markwalder, Prabhakar K. Jadhav, L. Li, Steven P. Seitz, C.-H. Chang, Susan Erickson-Viitanen, Charles J. Eyermann, Patrick Y.S. Lam, D. M. Kornhauser, L. Shum, Lee T. Bacheler, David A. Jackson, W. F. Daneker, Ronald M. Klabe
Publikováno v:
Journal of medicinal chemistry. 39(18)
High-resolution X-ray structures of the complexes of HIV-1 protease (HIV-1PR) with peptidomimetic inhibitors reveal the presence of a structural water molecule which is hydrogen bonded to both the mobile flaps of the enzyme and the two carbonyls flan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca252d7787d2a50a77209a603a4cff0c
https://pubmed.ncbi.nlm.nih.gov/8784449
https://pubmed.ncbi.nlm.nih.gov/8784449
Publikováno v:
American journal of hospital pharmacy. 49(12)
The prevalence and course of renal dysfunction in hospitalized patients and the prescribing of renally eliminated drugs in these patients were studied. All adult inpatients at a large teaching hospital who had a serum creatinine concentration assay p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c5304eab49b7a6f2076fccb6a3eac548
https://pubmed.ncbi.nlm.nih.gov/1481798
https://pubmed.ncbi.nlm.nih.gov/1481798
In vitro studies of zidovudine (ZDV) phosphorylation may not accurately reflect the in vivo dose-response relationship, which is crucial to determining the relationship between ZDV exposure, efficacy, and toxicity. However, measurement of ZDV phospho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a72c2f9e32444444923b1454f32a4b30
https://europepmc.org/articles/PMC284356/
https://europepmc.org/articles/PMC284356/
Autor:
Patricia Barditch-Crovo, Charles Flexner, Paul S. Lietman, Craig W. Hendrix, H Farzadegan, D M Kornhauser, L J Nerhood, Brent G. Petty, K J Lorentsen
Publikováno v:
Antiviral Research. 15:125
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::930db8c157a86c7cb3cf2c21ecfe4e6c
https://doi.org/10.1016/0166-3542(91)90240-r
https://doi.org/10.1016/0166-3542(91)90240-r