Zobrazeno 1 - 9
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pro vyhledávání: '"D M Engman"'
Publikováno v:
The Journal of Immunology. 144:3987-3991
Immunologic screening of cDNA expression libraries has been widely used for the identification of DNA sequences encoding the immunologically relevant proteins of many pathogenic microorganisms. For reasons that are not entirely clear, sequences encod
Autor:
D. M. Engman, J. S. Leon
Publikováno v:
World Class Parasites ISBN: 9781461348375
There are many potential mechanisms underlying the pathogenesis of chagasic heart disease. The frequent absence of parasites from the inflamed heart tissue of chronically infected individuals suggests that the disease may be, in part, autoimmune in n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed1be4a074fc55845bd6c930709f806d
https://doi.org/10.1007/978-1-4419-9206-2_9
https://doi.org/10.1007/978-1-4419-9206-2_9
Publikováno v:
FEMS microbiology letters. 166(1)
A full length cDNA encoding a novel Trypanosoma cruzi DnaJ protein was cloned and characterized. The 324 amino acid protein encoded by the cDNA (TcDJ1) displays a characteristics J-domain, but lacks the Gly-Phe and zinc finger regions present in some
Publikováno v:
Molecular and biochemical parasitology. 91(2)
We have molecularly cloned four members of the DnaJ (heat shock protein 40) family of protein chaperones of the protozoan parasite Trypanosoma cruzi--tcj1, tcj2, tcj3 and tcj4. While all the proteins contain defining J domains at their N-termini, onl
Autor:
C L, Olson, K C, Nadeau, M A, Sullivan, A G, Winquist, J E, Donelson, C T, Walsh, D M, Engman
Publikováno v:
The Journal of biological chemistry. 269(5)
An analysis of the genetic organization, regulated expression and biochemical properties of the cytoplasmic/nuclear (hsp70) and mitochondrial (mtp70) 70-kDa heat shock proteins of Trypanosoma cruzi is presented. The two proteins are encoded by tandem
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(3)
An inflammatory cardiomyopathy may develop in humans and experimental animals with chronic Trypanosoma cruzi infection (Chagas' disease). Among the possible mechanisms involved in the pathogenesis of Chagas' cardiomyopathy, induction of heart-specifi
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 144(10)
Immunologic screening of cDNA expression libraries has been widely used for the identification of DNA sequences encoding the immunologically relevant proteins of many pathogenic microorganisms. For reasons that are not entirely clear, sequences encod
Publikováno v:
The Journal of biological chemistry. 264(31)
A 24-kDa protein of Trypanosoma cruzi, the protozoan parasite that causes Chagas' disease, is recognized by antisera from both humans and experimental animals infected with this organism. Near its C terminus are two regions that have sequence similar
Publikováno v:
The Journal of biological chemistry. 263(25)
A ubiquitin encoding cDNA from Trypanosoma cruzi, the protozoan cause of Chagas' disease, was isolated by immunoscreening a lambda gt11 expression library with serum from a mouse chronically infected with this parasite. The cDNA encodes a precursor p