Zobrazeno 1 - 10
of 20
pro vyhledávání: '"D M Eccles"'
Autor:
A C, Antoniou, A P, Cunningham, J, Peto, D G, Evans, F, Lalloo, S A, Narod, H A, Risch, J E, Eyfjord, J L, Hopper, M C, Southey, H, Olsson, O, Johannsson, A, Borg, B, Pasini, B, Passini, P, Radice, S, Manoukian, D M, Eccles, N, Tang, E, Olah, H, Anton-Culver, E, Warner, J, Lubinski, J, Gronwald, B, Gorski, L, Tryggvadottir, K, Syrjakoski, O-P, Kallioniemi, H, Eerola, H, Nevanlinna, P D P, Pharoah, D F, Easton
Publikováno v:
Antoniou, AC; Cunningham, AP; Peto, J; Evans, DG; Lalloo, F; Narod, SA; et al.(2008). The BOADICEA model of genetic susceptibility to breast and ovarian cancers: Updates and extensions. British Journal of Cancer, 98(8), 1457-1466. doi: 10.1038/sj.bjc.6604305. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8tc5d3q2
British Journal of Cancer
Europe PubMed Central
Antoniou, A C, Cunningham, A P, Peto, J, Evans, D G, Lalloo, F, Narod, S A, Risch, H A, Eyfjord, J E, Hopper, J L, Southey, M C, Olsson, H, Johannsson, O, Borg, A, Pasini, B, Radice, P, Manoukian, S, Eccles, D M, Tang, N, Olah, E, Anton-Culver, H, Warner, E, Lubinski, J, Gronwald, J, Gorski, B, Tryggvadottir, L, Syrjakoski, K, Kallioniemi, O P, Eerola, H, Nevanlinna, H, Pharoah, P D P & Easton, D F 2008, ' The BOADICEA model of genetic susceptibility to breast and ovarian cancers : Updates and extensions ', British Journal of Cancer, vol. 98, no. 12, pp. 1457-1466 . https://doi.org/10.1038/sj.bjc.6604411
British Journal of Cancer
Europe PubMed Central
Antoniou, A C, Cunningham, A P, Peto, J, Evans, D G, Lalloo, F, Narod, S A, Risch, H A, Eyfjord, J E, Hopper, J L, Southey, M C, Olsson, H, Johannsson, O, Borg, A, Pasini, B, Radice, P, Manoukian, S, Eccles, D M, Tang, N, Olah, E, Anton-Culver, H, Warner, E, Lubinski, J, Gronwald, J, Gorski, B, Tryggvadottir, L, Syrjakoski, K, Kallioniemi, O P, Eerola, H, Nevanlinna, H, Pharoah, P D P & Easton, D F 2008, ' The BOADICEA model of genetic susceptibility to breast and ovarian cancers : Updates and extensions ', British Journal of Cancer, vol. 98, no. 12, pp. 1457-1466 . https://doi.org/10.1038/sj.bjc.6604411
Multiple genetic loci confer susceptibility to breast and ovarian cancers. We have previously developed a model (BOADICEA) under which susceptibility to breast cancer is explained by mutations in BRCA1 and BRCA2, as well as by the joint multiplicativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1e8c2383660f65496b5c8e17f96ee0
https://doi.org/10.1038/sj.bjc.6604411
https://doi.org/10.1038/sj.bjc.6604411
Autor:
B K Eccles, E R Copson, R I Cutress, T Maishman, D G Altman, P Simmonds, S M Gerty, L Durcan, L Stanton, D M Eccles, D Eccles, P Pharoah, R Warren, F Gilbert, L Jones, R Eeles, D G R Evans, A Hanby, A Thompson, S Hodgson, H Hammad, S Lakhani
Publikováno v:
The British journal of surgery. 102(8)
Background Young patients presenting to surgical clinics with breast cancer are usually aware of their family history and frequently believe that a positive family history may adversely affect their prognosis. Tumour pathology and outcomes were compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981d7fdc0262ca60daf94aff3ea58e2b
https://pubmed.ncbi.nlm.nih.gov/25989914
https://pubmed.ncbi.nlm.nih.gov/25989914
Autor:
B. B. Cohen, D. M. Eccles, A. Lessels, L. Taylor, C. M. Steel, John F. Smyth, Hani Gabra, R. C. F. Leonard
Publikováno v:
British Journal of Cancer
Allele imbalance on chromosome 11 loci in ovarian cancer is a frequent event, suggesting the presence of tumour-suppressor genes for ovarian carcinogenesis on this chromosome. Ten highly polymorphic (CA) repeat microsatellites were used to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e98604f31b2da92c30e6f019eda33a
https://doi.org/10.1038/bjc.1995.340
https://doi.org/10.1038/bjc.1995.340
Publikováno v:
British Journal of Cancer
Mouse monoclonal antibodies PAb 240 and PAb 1801 which specifically immunoprecipitate p53 protein, were used to examine 27 fresh ovarian tumours (16 serous adenocarcinomas, six endometrioid carcinomas, one mucinous adenocarcinoma, one mucinous border
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f230fb400ca90607459b80194535fe96
https://doi.org/10.1038/bjc.1992.8
https://doi.org/10.1038/bjc.1992.8
Publikováno v:
Journal of medical genetics. 37(3)
A family history of breast cancer has long been recognised as a significant risk factor for breast cancer. Quantifying that risk has been approached in publications and practically in a number of different ways. Increasingly regional genetics departm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::626ca9957b3a4f0a71acc3df02a7c49c
https://pubmed.ncbi.nlm.nih.gov/10699057
https://pubmed.ncbi.nlm.nih.gov/10699057
Publikováno v:
Disease Markers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95adc001fc177886362933b35a0d7081
https://pubmed.ncbi.nlm.nih.gov/10595276
https://pubmed.ncbi.nlm.nih.gov/10595276
Autor:
D M Eccles, Y Wallis, S McKay, D Morton, P W Lunt, F MacDonald, M Griffiths, B Sandhu, J Shea-Simonds
Publikováno v:
Archives of disease in childhood. 77(5)
Familial adenomatous polyposis (FAP) is a dominantly inherited predisposition to the development of many hundreds to thousands of adenomatous polyps of the colon. The mean age of onset is around 15 years, symptoms may arise in the third decade, and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15521ad188ab7d5fd4b56c9dbfb539b8
https://pubmed.ncbi.nlm.nih.gov/9487968
https://pubmed.ncbi.nlm.nih.gov/9487968
Autor:
D M, Eccles, R, van der Luijt, C, Breukel, H, Bullman, D, Bunyan, A, Fisher, J, Barber, C, du Boulay, J, Primrose, J, Burn, R, Fodde
Publikováno v:
American journal of human genetics. 59(6)
Desmoid tumors are slowly growing fibrous tumors highly resistant to therapy and often fatal. Here, we report hereditary desmoid disease (HDD), a novel autosomal dominant trait with 100% penetrance affecting a three-generation kindred. Desmoid tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8a9eecad72dc8480b4c0ca38c7aa2793
https://pubmed.ncbi.nlm.nih.gov/8940262
https://pubmed.ncbi.nlm.nih.gov/8940262
Autor:
D M, Eccles
Publikováno v:
British journal of hospital medicine. 56(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::775c33f017bf5458201be31fd47a8fb2
https://pubmed.ncbi.nlm.nih.gov/8909717
https://pubmed.ncbi.nlm.nih.gov/8909717
Autor:
I K, Temple, D M, Eccles, R M, Winter, M, Baraitser, S B, Carr, D, Shortland, M C, Jones, C, Curry
Publikováno v:
Clinical dysmorphology. 4(2)
Five children are described with a striking, asymmetric facial appearance, craniosynostosis, preaxial polysyndactyly, agenesis of the corpus callosum and unusual skin with streaky areas of atrophy. The gut and mucous membranes are involved in two pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b5ac2946b08c976814532b79686d34b8
https://pubmed.ncbi.nlm.nih.gov/7606318
https://pubmed.ncbi.nlm.nih.gov/7606318