Zobrazeno 1 - 5
of 5
pro vyhledávání: '"D M, van der Kolk"'
Autor:
D M, van der Kolk, E G, de Vries, W J, van Putten, L F, Verdonck, G J, Ossenkoppele, G E, Verhoef, E, Vellenga
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(8)
Despite treatment with intensive chemotherapy, a considerable number of patients with acute myeloid leukemia (AML) die from their disease due to the occurrence of resistance. Overexpression of the transporter proteins P-glycoprotein (P-gp) and multid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cf869d1a22b3480653d34b7b3f6d4396
https://pubmed.ncbi.nlm.nih.gov/10955805
https://pubmed.ncbi.nlm.nih.gov/10955805
Autor:
D M, van Der Kolk, E, Vellenga, A Y, van Der Veen, L, Noordhoek, H, Timmer-Bosscha, G J, Ossenkoppele, R A, Raymakers, M, Müller, E, van Den Berg, E G, de Vries
Publikováno v:
Blood. 95(11)
Deletion of the multidrug resistance gene MRP1 has been demonstrated in acute myeloid leukemia (AML) patients with inversion of chromosome 16 (inv[16]). These AML patients are known to have a relatively favorable prognosis, which suggests that MRP1 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0b7612c159350c81cef001eb6a3c5c2
https://pubmed.ncbi.nlm.nih.gov/10828037
https://pubmed.ncbi.nlm.nih.gov/10828037
Autor:
G L, Scheffer, M, Maliepaard, A C, Pijnenborg, M A, van Gastelen, M C, de Jong, A B, Schroeijers, D M, van der Kolk, J D, Allen, D D, Ross, P, van der Valk, W S, Dalton, J H, Schellens, R J, Scheper
Publikováno v:
Cancer research. 60(10)
Tumor cells may display a multidrug resistant phenotype by overexpression of ATP-binding cassette transporters such as multidrug resistance (MDRI) P-glycoprotein, multidrug resistance protein 1 (MRP1), and breast cancer resistance protein (BCRP). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1813380e63045c31cdfc3ce59d7717d6
https://pubmed.ncbi.nlm.nih.gov/10825126
https://pubmed.ncbi.nlm.nih.gov/10825126
Publikováno v:
Advances in experimental medicine and biology. 457
Multidrug resistance (MDR), which is cross-resistance to structurally and functionally unrelated drugs such as anthracyclines, epipodophyllotoxins and vinca alkaloids, is a major cause of treatment failure in malignant disorders. Known mechanisms of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7bfb4f23c7e44ee0ad1829cf593d2cfa
https://pubmed.ncbi.nlm.nih.gov/10500793
https://pubmed.ncbi.nlm.nih.gov/10500793
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(7)
To develop a functional assay for the activity of the multidrug resistance protein 1 (MRP1), we tested whether carboxyfluorescein (CF) was specifically transported by MRP and whether this transport pump could be specifically blocked by the leukotrien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad26163e40e9a1fc13cfc1fba4c2aece
https://pubmed.ncbi.nlm.nih.gov/9676848
https://pubmed.ncbi.nlm.nih.gov/9676848