Výsledky vyhledávání - "D M, de Groot"

Serum sex hormone-binding globulin levels are reduced and inversely associated with intrahepatic lipid content and saturated fatty acid fraction in adult patients with glycogen storage disease type 1a

Autor: P I H G, Simons, O, Valkenburg, I, Telgenkamp, K M, van der Waaij, D M, de Groot, P, Veeraiah, J A P, Bons, T G J, Derks, C G, Schalkwijk, V B, Schrauwen-Hinderling, C D A, Stehouwer, M C G J, Brouwers

Publikováno v: Journal of endocrinological investigation. 45(6)

De novo lipogenesis has been inversely associated with serum sex hormone-binding globulin (SHBG) levels. However, the directionality of this association has remained uncertain. We, therefore, studied individuals with glycogen storage disease type 1a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e6928a6c804433e99c82b03fc7164662
https://pubmed.ncbi.nlm.nih.gov/35132570

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p38 inhibition and not MK2 inhibition enhances the secretion of chemokines from TNF-α activated rheumatoid arthritis fibroblast-like synoviocytes

Autor: J, Dulos, F P G, Wijnands, J A J, van den Hurk-van Alebeek, M J H, van Vugt, J A C, Rullmann, J-J G, Schot, M W G D M, de Groot, J L, Wagenaars, R, van Ravestein-van Os, R L, Smets, P M, Vink, C L, Hofstra, R L H, Nelissen, H, van Eenennaam

Publikováno v: Clinical and experimental rheumatology. 31(4)

For many years the p38 MAP kinase (MAPK) has been a major anti-inflammatory target for the development of an oral therapy for rheumatoid arthritis (RA). However, disappointing results from Phase II clinical studies suggest that adaptations may occur,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5f92a6fea16aca2634734f2c4d693359
https://pubmed.ncbi.nlm.nih.gov/23558031

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Don't judge a neuron only by its cover: neuronal function in in vitro developmental neurotoxicity testing

Autor: Remco H.S. Westerink, Martje W G D M de Groot, Milou M.L. Dingemans

Publikováno v: Toxicological sciences : an official journal of the Society of Toxicology. 132(1)

Classical cases of developmental neurotoxicity (DNT) in humans and advances in risk assessment methods did not prevent the emergence of new chemicals with (suspected) DNT potential. Exposure to these chemicals may be related to the increased worldwid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8304616541dc48a886cbdd4acd0e9df
https://pubmed.ncbi.nlm.nih.gov/22961093

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Effects of atropine sulphate on seizure activity and brain damage produced by soman in guinea-pigs: ECoG correlates of neuropathology

Autor: P, Carpentier, A, Foquin, G, Rondouin, M, Lerner-Natoli, D M, de Groot, G, Lallement

Publikováno v: Neurotoxicology. 21(4)

The present study describes the effects of pyridostigmine (PYR; 0.2 mg/kg) and atropine sulphate (AS; 5 mg/kg) on guinea-pigs intoxicated by a high dose (2xLD50) of the organophosphate compound, soman, an irreversible inhibitor of acetylcholinesteras

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e79a4d3a53b8b6d6746caf27084e1046
https://pubmed.ncbi.nlm.nih.gov/11022861

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The effect of shape assumptions on the estimation of the numerical density of synapses from thin sections

Autor: R W, Verwer, D M, De Groot

Publikováno v: Progress in brain research. 55

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1d71bb11fac87e7e4c7363e30ab2b5a8
https://pubmed.ncbi.nlm.nih.gov/7163491

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