Zobrazeno 1 - 10
of 42
pro vyhledávání: '"D M, Stocco"'
Publikováno v:
Journal of Neuroendocrinology. 19:860-869
Neurosteroids are steroids synthesised by brain cells. The molecular mechanism of neurosteroidogenesis from cholesterol has not yet been revealed. We studied the potential role of the steroidogenic acute regulatory (StAR) protein in neurosterodogenes
Publikováno v:
Journal of Endocrinology. 175:793-801
The LH signal transduction pathway features the activation of protein tyrosine phosphatases (PTPs) as one of the components of a cascade that includes other well characterized events such as cAMP-dependent protein kinase A (PKA) activation. Moreover,
Autor:
William E. Rainey, J. B. Seely, Rosa Sirianni, Bruce R. Carr, George R. Attia, Vincenzo Pezzi, D. M. Stocco
Publikováno v:
Scopus-Elsevier
In the current study we test the hypothesis that liver receptor homologue-1 (LRH; designated NR5A2) is involved in the regulation of steroid hormone production. The potential role of LRH was assessed by first examining expression in human steroidogen
Publikováno v:
Endocrinology. 137:4522-4525
In an experimental endotoxemia model utilizing mice, serum testosterone was found to be decreased 90% two h post ip injection of 200 micrograms of lipopolysaccharide (LPS). This decrease was sustained for 9 days. The early depression of serum testost
Autor:
S. R. King, L. KüHNE, A. Jankowska, Focko F. G. Rommerts, G. W. A. Van Cappellen, D. M. Stocco
Publikováno v:
Journal of Endocrinology, 181, 169-178. Bioscientifica Ltd
The mechanism by which ethane 1,2-dimethanesulfonate (EDS) selectively kills Leydig cells is poorly understood. To characterize further the cell-specific actions of EDS, we studied biochemical and morphological changes during apoptosis in different L
Publikováno v:
The Journal of endocrinology. 170(3)
Nutritional factors, especially phytoestrogens, have been extensively studied for their potential beneficial effects against hormone-dependent and age-related diseases. The present study describes the short-term effects of dietary phytoestrogens on r
Publikováno v:
Endocrinology. 142(1)
Recently, we demonstrated that triiodothyronine (T(3)) stimulated steroid hormone biosynthesis and steroidogenic acute regulatory (StAR) protein expression in mLTC-1 mouse Leydig tumor cells through the mediation of steroidogenic factor 1 (SF-1). We
Publikováno v:
Molecular reproduction and development. 57(4)
We report the generation of stable cell lines obtained by spontaneous immortalization of primary cultures of porcine granulosa cells. Three hundred stable cell lines were obtained from three independent immortalization trials. Two of these cell lines
Autor:
L P, Walsh, D M, Stocco
Publikováno v:
Biology of reproduction. 63(4)
Lindane, the gamma isomer of hexachlorocyclohexane (HCH), is one of the oldest synthetic pesticides still in use worldwide. Numerous reports have shown that this pesticide adversely affects reproductive function in animals. Although the pathogenesis
Autor:
D M, Stocco
Publikováno v:
Medicina. 59(5 Pt 2)