Zobrazeno 1 - 10
of 12
pro vyhledávání: '"D M, Slater"'
Autor:
D M Slater, Andrea A. Mosher, Hayley S. Levinson, Brigitta Riley, Stephen L. Wood, Angela E. Vinturache, Kelly J. Rainey
Publikováno v:
Reproductive Sciences. 21:921-929
Prostaglandins are implicated in the labor process, yet the precise role and regulation of the prostaglandin pathway remains to be elucidated. The first step in the pathway is cleavage of membrane phospholipids by phospholipase A2 (PLA2). Previous wo
Autor:
Mark Bieda, D M Slater, Anna Miller-Larsson, Curtis Dumonceaux, Suharsh Shah, Mahmoud M. Mostafa, Cora Kooi, Margaret M. Kelly, Robert Newton, Suzanne L. Traves, Elizabeth M. King, Christopher F. Rider, Andrew McWhae, Richard Leigh, Tyler Kolisnik
Publikováno v:
Pharmacology Research & Perspectives
Although inhaled glucocorticoids, or corticosteroids (ICS), are generally effective in asthma, understanding their anti‐inflammatory actions in vivo remains incomplete. To characterize glucocorticoid‐induced modulation of gene expression in the h
Publikováno v:
MHR: Basic science of reproductive medicine. 13:69-75
Since the controversies regarding the use of non-steroidal anti-inflammatory drugs (NSAIDs) and selective cyclo-oxygenase (COX)-2 antagonists for the treatment of preterm labour (PTL), more emphasis has been placed on investigating the terminal synth
Publikováno v:
Facts, Views & Vision in ObGyn
Preterm birth (PTB) remains the most common cause of neonatal morbidity and mortality as well as long-term disability. Current strategies to prevent or arrest spontaneous preterm labor (SPTL) have limited success. For almost three decades, there have
Autor:
Simon R. Bartlett, Phillip R. Bennett, Giovanni E. Mann, W Dennes, Lucilla Poston, D M Slater, Juan S. Campa, Robin Poston
Publikováno v:
The Journal of Physiology. 521:705-716
The initiation of labour in pregnant women is poorly understood. Uterine muscle is responsive both to labour ‘promoting’ and labour ‘inhibitory’ stimuli, and quiescent factors have been suggested to predominate during gestation. The mechanism
Publikováno v:
American Journal of Obstetrics and Gynecology. 180:103-109
The purpose of this study was to identify the isoforms and splicing patterns of prostaglandin H synthase present in pregnant human lower-segment myometrium and determine whether there is differential expression of the isoforms or splice variants with
Publikováno v:
American journal of reproductive immunology (New York, N.Y. : 1989). 43(5)
Preterm labor remains the major cause of perinatal mortality and morbidity in normally formed babies. The mechanisms involved in the onset of preterm labor are poorly understood, mainly because the mechanisms initiating term labor remain ill-defined.
Publikováno v:
Prostaglandins. 51(2)
In previous studies we have shown that IL-1 beta induced both PGE2 release and total cellular cPLA2 activity and cPLA2 protein synthesis in human amnion-derived WISH cells. In this study, the effect of IL-1 beta on cPLA2 and PGHS-2 mRNA expression wa
Publikováno v:
Biochemical and biophysical research communications. 203(1)
The onset of labour is associated with an increase in prostaglandin synthesis in amnion which appears to be mediated at least in part by an increase in cyclo-oxygenase (COX) expression. We have tested the hypothesis that COX expression is controlled
Publikováno v:
Progress in Radiopharmacy ISBN: 9789401084109
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::053699fb0b5e8c14f6e0a3891fe5789d
https://doi.org/10.1007/978-94-009-4297-4_27
https://doi.org/10.1007/978-94-009-4297-4_27