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A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

Autor: N A, Thornberry, T A, Rano, E P, Peterson, D M, Rasper, T, Timkey, M, Garcia-Calvo, V M, Houtzager, P A, Nordstrom, S, Roy, J P, Vaillancourt, K T, Chapman, D W, Nicholson

Publikováno v: The Journal of biological chemistry. 272(29)

There is compelling evidence that members of the caspase (interleukin-1beta converting enzyme/CED-3) family of cysteine proteases and the cytotoxic lymphocyte-derived serine protease granzyme B play essential roles in mammalian apoptosis. Here we use

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ec834dddf3c7a76da30f42cac465fbb3
https://pubmed.ncbi.nlm.nih.gov/9218414

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