Zobrazeno 1 - 10
of 14
pro vyhledávání: '"D M, Raben"'
Autor:
B, Tu-Sekine, D M, Raben
Publikováno v:
Methods in enzymology. 583
This section provides detailed protocols for the analysis of a mammalian diacylglycerol kinase, DGKθ, including an activity assay, a kinetic analysis, preparation of small unilamellar vesicles, and a vesicle pulldown assay. The goal of this section
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b2184117e1c140026894b0e473cbc3ba
https://pubmed.ncbi.nlm.nih.gov/28063493
https://pubmed.ncbi.nlm.nih.gov/28063493
Autor:
D M, Raben, J J, Baldassare
Publikováno v:
European Journal of Histochemistry, Vol 44, Iss 1, Pp 67-80 (2009)
Since the early 1980’s, there has been an explosion of research in an area often described as “signal transduction”. Loosely defined, signal transduction refers to the communication of a signal initiated by an extracellular agonist to the cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dc626974935e0d6ac082684807de5be1
http://ejh.pagepress.org/index.php/ejh/article/view/1576
http://ejh.pagepress.org/index.php/ejh/article/view/1576
Publikováno v:
Journal of Biological Chemistry. 267:21816-21822
The mechanism by which an agonist, binding to a cell surface receptor, exerts an effect on events in the nucleus is not known. We have previously shown (Leach, K. L., Ruff, V. A., Wright, T. M., Pessin, M. S., and Raben, D. M. (1991) J. Biol. Chem. 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ef13f86ab2cb56a4d396954f7cfc01a
https://doi.org/10.1016/s0021-9258(19)36685-2
https://doi.org/10.1016/s0021-9258(19)36685-2
Publikováno v:
Journal of Biological Chemistry. 266:3215-3221
Diacylglycerols (DAGs) derived from phosphatidylcholine (PC) hydrolysis have been shown to activate protein kinase C (PKC) in vitro, but it is not known whether this event occurs in response to DAGs generated via agonist-induced PC hydrolysis in inta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cdcbb0421aa9ddca43fbfb7658f7ab8
https://doi.org/10.1016/s0021-9258(18)49976-0
https://doi.org/10.1016/s0021-9258(18)49976-0
Autor:
B, Tu-Sekine, D M, Raben
Publikováno v:
European journal of histochemistry : EJH. 48(1)
The story of nuclear diacyglycerol is proving to be a complex one. Sub-pools of nuclear diglyceride that differ in their metabolism, nuclear localization and temporal regulation have been identified, suggesting potentially diverse signaling functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::436561c68f4c1f97f2a38d43db52e250
https://pubmed.ncbi.nlm.nih.gov/15145778
https://pubmed.ncbi.nlm.nih.gov/15145778
Publikováno v:
The Biochemical journal. 337
Addition of alpha-thrombin to quiescent IIC9 cells results in the activation of lipid-metabolizing enzymes associated with signal-transduction cascades. These enzymes include phosphatidylinositol (PI)-specific phospholipase C (PI-PLC), phosphatidylch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7d2c151a6218cf8c624f92f5e68da1c
https://pubmed.ncbi.nlm.nih.gov/9854030
https://pubmed.ncbi.nlm.nih.gov/9854030
Publikováno v:
The Journal of biological chemistry. 272(52)
Platelet-derived growth factor (PDGF)-induced Ras activation is required for G1 progression in Chinese hamster embryo fibroblasts (IIC9 cells). Ras stimulates both extracellular signal-related kinase (ERK) activation and RhoA activation in response t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77a852cfa981d57fc6c8859f5232e363
https://pubmed.ncbi.nlm.nih.gov/9407076
https://pubmed.ncbi.nlm.nih.gov/9407076
Publikováno v:
The Journal of biological chemistry. 268(13)
The trypanosome variant surface glycoprotein (VSG) is anchored to the outer leaflet of the parasite plasma membrane by a glycosyl phosphatidylinositol (GPI). The VSG anchor is unique among GPIs in containing exclusively dimyristoylglycerol as its lip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3df0199a23bbee046dd2fd73b8042103
https://pubmed.ncbi.nlm.nih.gov/8486622
https://pubmed.ncbi.nlm.nih.gov/8486622
Publikováno v:
The Journal of biological chemistry. 266(5)
Diacylglycerols (DAGs) derived from phosphatidylcholine (PC) hydrolysis have been shown to activate protein kinase C (PKC) in vitro, but it is not known whether this event occurs in response to DAGs generated via agonist-induced PC hydrolysis in inta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::68e321000b7ddbec7eaa3ef56fdf6419
https://pubmed.ncbi.nlm.nih.gov/1993695
https://pubmed.ncbi.nlm.nih.gov/1993695
Publikováno v:
The Journal of biological chemistry. 265(14)
Recent studies have implicated the hydrolysis of phosphoinositides and phosphatidylcholine in agonist-stimulated events. The potent mitogen, alpha-thrombin, stimulates the generation of diglycerides in a biphasic and sustained manner in IIC9 fibrobla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69471788fd988a417be7c0062a54ba7e
https://pubmed.ncbi.nlm.nih.gov/2335511
https://pubmed.ncbi.nlm.nih.gov/2335511