Zobrazeno 1 - 10
of 32
pro vyhledávání: '"D M, Peehl"'
Autor:
D M, Peehl
Publikováno v:
Reviews in urology. 3
New developments in molecular and cellular biology are rapidly increasing knowledge of the mechanisms of androgen action in the prostate. Molecular profiling of recurrent cancer after androgen deprivation therapy has revealed genetic changes related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5c1676c7c5aede5021a2036ce4ab1330
https://pubmed.ncbi.nlm.nih.gov/16986004
https://pubmed.ncbi.nlm.nih.gov/16986004
Publikováno v:
The Journal of urology. 166(4)
We examined the association of androgen receptor gene cytosine-adenine-guanine (CAG) repeat length and the 2 single nucleotide polymorphisms A49T and V89L in the type II 5 alpha-reductase gene with prostate enlargement measured as the weight of the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7cb1a46baf7c62fef488ab02ab889c49
https://pubmed.ncbi.nlm.nih.gov/11547131
https://pubmed.ncbi.nlm.nih.gov/11547131
Publikováno v:
Cancer research. 61(7)
Evidence from epidemiological, molecular, and genetic studies suggests a role for vitamin D in the development and/or progression of prostate cancer. In experimental models and clinical trials, 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] was shown to exer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::732b36edbbc59cbc52cbe29588800393
https://pubmed.ncbi.nlm.nih.gov/11306457
https://pubmed.ncbi.nlm.nih.gov/11306457
Publikováno v:
Cancer research. 61(5)
The androgen-signaling pathway is important in the growth and progression of prostate cancer. Androgen ablation therapy, which may result in programmed cell death, is often used to treat advanced prostate cancer. The growth-promoting effects of andro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04aafc57491901f253506f923a8b7195
https://pubmed.ncbi.nlm.nih.gov/11280774
https://pubmed.ncbi.nlm.nih.gov/11280774
Autor:
D M, Peehl, R G, Sellers
Publikováno v:
The Prostate. 45(2)
Initial efforts to develop in vitro models to study prostatic biology focused on the culture and characterization of epithelial cells. Recently, attention has turned towards inclusion of stromal cells in experimental systems.Improved methods to isola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::65f315faab068e90f513add9756a7eeb
https://pubmed.ncbi.nlm.nih.gov/11027410
https://pubmed.ncbi.nlm.nih.gov/11027410
p16INK4A mediates cyclin dependent kinase 4 and 6 inhibition in senescent prostatic epithelial cells
Publikováno v:
Cancer research. 60(10)
The senescence checkpoint constrains the proliferative potential of normal cells in culture to a finite number of cell doublings. In this study, we investigated the mechanism of cyclin dependent kinase (cdk) inhibition in senescent human prostatic ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dff8c05cdb12e51f69c9c06f220e1213
https://pubmed.ncbi.nlm.nih.gov/10825132
https://pubmed.ncbi.nlm.nih.gov/10825132
Publikováno v:
Anticancer research. 19(5B)
In vitro models of human prostatic carcinogenesis are increasingly available and include representatives of normal, immortal, tumorigenic and metastatic phenotypes. In this study, growth regulation of immortal, but non-tumorigenic, human papillomavir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::14d7cc294e46aa54c56d593b6b180225
https://pubmed.ncbi.nlm.nih.gov/10628324
https://pubmed.ncbi.nlm.nih.gov/10628324
Publikováno v:
Endocrinology. 140(3)
We have recently shown that 1alpha,25-dihydroxyvitamin D3 [1,25-(OH)2D3] inhibits proliferation of LNCaP cells, an androgen-responsive human prostate cancer cell line. Also, 1,25-(OH)2D3 increases androgen receptor (AR) abundance and enhances cellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac364ac5b7a88c24c39f1ecd406a7970
https://pubmed.ncbi.nlm.nih.gov/10067845
https://pubmed.ncbi.nlm.nih.gov/10067845
Autor:
M E, Stearns, J L, Ware, D B, Agus, C J, Chang, I J, Fidler, R S, Fife, R, Goode, E, Holmes, M S, Kinch, D M, Peehl, T G, Pretlow, G N, Thalmann
Publikováno v:
The Prostate. 36(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75ea6d794003daa3a0959c99a86ff73e
https://pubmed.ncbi.nlm.nih.gov/9650917
https://pubmed.ncbi.nlm.nih.gov/9650917
Autor:
D M, Peehl, R G, Sellers
Publikováno v:
The Prostate. 35(2)
We investigated the ability of a variety of growth factors to regulate the differentiation of prostatic fibroblasts into smooth muscle cells.Smooth muscle actin levels were monitored by immunoblot analysis and immunocytochemistry. Proliferation was m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb5fc8e44cf9acbe6291d6d4d4d83f44
https://pubmed.ncbi.nlm.nih.gov/9568676
https://pubmed.ncbi.nlm.nih.gov/9568676