Zobrazeno 1 - 10
of 18
pro vyhledávání: '"D M, Paulnock"'
Publikováno v:
The Journal of Immunology. 155:4933-4938
We have characterized the transcriptional response to IFN-gamma in two maturationally distinct macrophage populations: the mature RAW 264.7 cell line, phenotypically identical to thioglycollate-elicited peritoneal macrophages, and the less mature WEH
Autor:
C M Nicolet, D M Paulnock
Publikováno v:
The Journal of Immunology. 152:153-162
We have investigated the regulation of an activation-associated guanylate-binding protein gene (mGBP-1/mag-1) in murine macrophage cell lines in response to the cytokine IFN-gamma. One of the cell lines utilized (RAW 264.7) acquires the ability to ki
Autor:
D M Paulnock, L E Lambert
Publikováno v:
The Journal of Immunology. 144:765-773
Macrophage activation for tumor cell killing is a multistep pathway in which responsive macrophages interact sequentially with priming and triggering stimuli in the acquisition of full tumoricidal activity. A number of mediators have been identified
Autor:
S P, Coller, D M, Paulnock
Publikováno v:
Journal of leukocyte biology. 70(1)
Scavenger receptors are macrophage cell surface molecules associated with endocytic uptake of lipoproteins and binding of microbial ligands. Macrophage class A scavenger receptors (SR-As) interact with ligands to induce cellular signaling leading to
Autor:
D M, Paulnock, S P, Coller
Publikováno v:
Journal of leukocyte biology. 69(5)
African trypanosomes cause a fatal disease of man and animals that is characterized by extensive functional, histological, and pathological changes in the lymphoid tissues of infected hosts, including an increase in the numbers and activation state o
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(4)
We are interested in understanding the molecular basis of macrophage (Mphi) differentiation and activation by cytokines. Recent reports have suggested that the transcription factor STAT5 may play a role in Mphi differentiation. In the experiments des
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(9)
We previously demonstrated that the macrophage cell lines RAW 264.7 and WEHI-3 exhibit distinct patterns of gene expression in response to IFN-gamma. This difference is controlled at the transcriptional level and results from a specific inability of
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 155(10)
We have characterized the transcriptional response to IFN-gamma in two maturationally distinct macrophage populations: the mature RAW 264.7 cell line, phenotypically identical to thioglycollate-elicited peritoneal macrophages, and the less mature WEH
Autor:
C M, Nicolet, D M, Paulnock
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 152(1)
We have investigated the regulation of an activation-associated guanylate-binding protein gene (mGBP-1/mag-1) in murine macrophage cell lines in response to the cytokine IFN-gamma. One of the cell lines utilized (RAW 264.7) acquires the ability to ki
Autor:
D M, Paulnock
Publikováno v:
Immunology series. 60