Leptospira Leptolysin Contributes to Serum Resistance but Is Not Essential for Acute Infection.

Autor: Dos Santos Courrol D; Laboratory of Bacteriology, Butantan Institute, São Paulo, Brazil.; Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Santos CM; Laboratory of Bacteriology, Butantan Institute, São Paulo, Brazil.; Laboratory of Bacterial Zoonosis, Department of Preventive Veterinary Medicine and Animal Health, School of Veterinary Medicine, University of São Paulo, São Paulo, Brazil., Chura-Chambi RM; Laboratory of Bacteriology, Butantan Institute, São Paulo, Brazil.; Center of Biotechnology, Energy and Nuclear Research Institute (IPEN)-CNEN/SP, São Paulo, Brazil., Morganti L; Center of Biotechnology, Energy and Nuclear Research Institute (IPEN)-CNEN/SP, São Paulo, Brazil., Avelar KES; Laboratório de Referência Nacional para Leptospirose, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil., de Moraes Maia F; Laboratório de Hantaviroses e Rickettsioses, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil., Rodrigues-da-Silva RN; Laboratório de Hantaviroses e Rickettsioses, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil., Wunder EA Jr; Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, Connecticut, USA.; Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut, USA.; Instituto Gonçalo Moniz, Fundação Oswaldo Cruz, Ministério da Saúde, Salvador, Brazil., Barbosa AS; Laboratory of Bacteriology, Butantan Institute, São Paulo, Brazil.

Publikováno v: Molecular microbiology [Mol Microbiol] 2024 Nov; Vol. 122 (5), pp. 720-729. Date of Electronic Publication: 2024 Nov 01.

UK5099 Inhibits the NLRP3 Inflammasome Independently of its Long‐Established Target Mitochondrial Pyruvate Carrier.

Autor: Ran, Linyu^1,2 (AUTHOR), Chen, Miao³ (AUTHOR), Ye, Jihui^1,2 (AUTHOR), Zhang, Song^4,5 (AUTHOR), Luo, Zhibing^1,2 (AUTHOR), Bai, Tengfei⁶ (AUTHOR), Qian, Chenchen⁷ (AUTHOR), Zhou, Quan^1,2 (AUTHOR), Shan, Mengtian^1,2 (AUTHOR), Chu, Yong⁶ (AUTHOR), Herrmann, Joerg⁴ (AUTHOR), Li, Qiang¹ (AUTHOR) liqressh@tongji.edu.cn, Wang, Feilong¹ (AUTHOR) wang_feilong@tongji.edu.cn

Publikováno v: Advanced Science. 9/4/2024, Vol. 11 Issue 33, p1-18. 18p.

Subcellular localization of perforin and serine esterase in lymphokine-activated killer cells and cytotoxic T cells by immunogold labeling

Autor: D M Ojcius, L M Zheng, E C Sphicas, A Zychlinsky, J D Young

Publikováno v: The Journal of Immunology. 146:4427-4432

CTL, NK cells, and lymphokine-activated killer (LAK) cells are cytolytic lymphocytes known to produce a pore-forming protein, named perforin or cytolysin, that lyses target cells by forming large pores on the plasma membrane of the target cell. Other

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5e36379ed2959d9c6cb720fde8901010
https://doi.org/10.4049/jimmunol.146.12.4427

Idiopathic Pulmonary Fibrosis Caused by Damaged Mitochondria and Imbalanced Protein Homeostasis in Alveolar Epithelial Type II Cell.

Autor: Dong Z; Affiliated Cancer Hospital & Institute of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, School of Biomedical Engineering, Guangzhou Medical University, Guangzhou, 510260, China.; Institute of Biophysics, Chinese Academy of Sciences 15 Datun Road, Chaoyang District, Beijing, 100101, China.; College of Life Science, Mudanjiang Medical University, Mudanjiang, 157000, China., Wang X; Affiliated Cancer Hospital & Institute of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, School of Biomedical Engineering, Guangzhou Medical University, Guangzhou, 510260, China., Wang P; College of Life Science, Mudanjiang Medical University, Mudanjiang, 157000, China., Bai M; Affiliated Cancer Hospital & Institute of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, School of Biomedical Engineering, Guangzhou Medical University, Guangzhou, 510260, China.; School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing, 100101, China., Wang T; School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing, 100101, China., Chu Y; College of Life Science, Mudanjiang Medical University, Mudanjiang, 157000, China., Qin Y; Affiliated Cancer Hospital & Institute of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, School of Biomedical Engineering, Guangzhou Medical University, Guangzhou, 510260, China.; Institute of Biophysics, Chinese Academy of Sciences 15 Datun Road, Chaoyang District, Beijing, 100101, China.

Publikováno v: Advanced biology [Adv Biol (Weinh)] 2024 Oct 10, pp. e2400297. Date of Electronic Publication: 2024 Oct 10.

Internalization of Chlamydia by dendritic cells and stimulation of Chlamydia-specific T cells

Autor: D M, Ojcius, Y, Bravo de Alba, J M, Kanellopoulos, R A, Hawkins, K A, Kelly, R G, Rank, A, Dautry-Varsat

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 160(3)

Chlamydia species are the causative agents of trachoma, various forms of pneumonia, and the most common sexually transmitted diseases. Although the infection cycle has been extensively characterized in epithelial cells, where the Chlamydia entry-vacu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0398bd5b6a4586fdf4c10819216716f1
https://pubmed.ncbi.nlm.nih.gov/9570547