Zobrazeno 1 - 10
of 24
pro vyhledávání: '"D M, Nanus"'
Autor:
D M, Nanus, D, Engelstein
Publikováno v:
Methods in molecular medicine. 53
A human renal cancer was first established in continuous culture in 1962. Currently, there are well over 100 different characterized renal cancer cell lines derived from both primary and metastatic renal cell carcinomas (RCCs) (1-3). The biological p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::64998a3afdb70a26ed8dddc62bec054c
https://pubmed.ncbi.nlm.nih.gov/21318799
https://pubmed.ncbi.nlm.nih.gov/21318799
Autor:
J, Dai, R, Shen, M, Sumitomo, J S, Goldberg, Y, Geng, D, Navarro, S, Xu, J A, Koutcher, M, Garzotto, C T, Powell, D M, Nanus
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(5)
Expression of neutral endopeptidase (NEP) 24.11 is diminished in metastatic, androgen-independent prostate cancers (PCs; C. N. Papandreou et al., NAT: MED:, 4: 50--57, 1998). To determine the effects on androgen-independent PC cells of overexpressing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::78f771c4ca3ee03c854305aa5018faaf
https://pubmed.ncbi.nlm.nih.gov/11350908
https://pubmed.ncbi.nlm.nih.gov/11350908
Publikováno v:
Cancer research. 61(8)
G-protein coupled receptor (GPCR) agonists such as neuropeptides activate the insulin-like growth factor-1 receptor (IGF-IR) or the serine-threonine protein kinase Akt, suggesting that neuropeptides-GPCR signaling can cross-communicate with IGF-IR-Ak
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9107fc0facf8cda0380fbc219e727fa6
https://pubmed.ncbi.nlm.nih.gov/11309283
https://pubmed.ncbi.nlm.nih.gov/11309283
Publikováno v:
Cancer research. 60(23)
Phorbol esters induce apoptosis in androgen-sensitive LNCaP cells, which express neutral endopeptidase (NEP), but not in androgen-independent prostate cancer (PC) cells, which lack NEP expression. We investigated the role of NEP in PC cell susceptibi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1aff94f63880d9bb3deaffc8b16ef79
https://pubmed.ncbi.nlm.nih.gov/11118039
https://pubmed.ncbi.nlm.nih.gov/11118039
Autor:
B A, Usmani, R, Shen, M, Janeczko, C N, Papandreou, W H, Lee, W G, Nelson, J B, Nelson, D M, Nanus
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(5)
Neutral endopeptidase 24.11 (NEP) is a cell surface peptidase expressed by prostatic epithelial cells that cleaves and inactivates neuropeptide growth factors implicated in the growth of androgen-independent prostate cancer (PC). Decreased NEP expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2db569506dc5645433bc6e10d37a0dbc
https://pubmed.ncbi.nlm.nih.gov/10815884
https://pubmed.ncbi.nlm.nih.gov/10815884
Publikováno v:
Seminars in oncology. 27(2)
Metastatic renal cell carcinoma remains one of the most treatment-resistant malignancies in humans. As such, long-term survival is limited to a minority of patients. Interferon-alpha and interleukin-2 induced major responses in some patients with ren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6e337dd924a9e6571601d7fd8a90c23c
https://pubmed.ncbi.nlm.nih.gov/10768602
https://pubmed.ncbi.nlm.nih.gov/10768602
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(3)
The evaluation of new therapies in prostate cancer requires unique end points for agents with diverse mechanisms of action. Because retinoic acid may have a confounding effect on prostate-specific antigen, we incorporated a pathological end point int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::359e5555c72bf0a17db2bf122bf9cce2
https://pubmed.ncbi.nlm.nih.gov/10741705
https://pubmed.ncbi.nlm.nih.gov/10741705
Autor:
W J, Berg, D M, Nanus, A, Leung, K T, Brown, B, Hutchinson, M, Mazumdar, X C, Xu, R, Lotan, V E, Reuter, R J, Motzer
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 5(7)
Retinoic acid receptor-beta (RAR-beta) mRNA is not expressed by retinoid-resistant renal cancer cell lines but is present in retinoid-sensitive SK-RC-06 renal cancer cells and increases following incubation with retinoic acid (RA), suggesting that th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::15983dfe0e04d061a7ea04fd0919f45d
https://pubmed.ncbi.nlm.nih.gov/10430067
https://pubmed.ncbi.nlm.nih.gov/10430067
Autor:
D M, Nanus
Publikováno v:
Cancer investigation. 17(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a43ec583b8b15847e9da9041a4b8b6dd
https://pubmed.ncbi.nlm.nih.gov/10370367
https://pubmed.ncbi.nlm.nih.gov/10370367
Autor:
Y, Geng, A, Biffi, D, Engelstein, E, Ronch, M, Faustini, H K, Lai, A P, Albino, G, Di Fronzo, D M, Nanus
Publikováno v:
Anticancer research. 18(1A)
Alpha interferon (IFN-alpha) is commonly used to treat patients with advanced renal cell carcinoma (RCC). We previously reported that resistance of RCCs to IFN-alpha in vitro correlated with the expression of a cell-surface glycoprotein of 160,00 kD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f47c2c01e9fd87ae27f3a7d94d5be5a7
https://pubmed.ncbi.nlm.nih.gov/9568047
https://pubmed.ncbi.nlm.nih.gov/9568047