Zobrazeno 1 - 6
of 6
pro vyhledávání: '"D M, Loeb"'
Publikováno v:
Leukemia, 14, 973-990. Nature Publishing Group
Scopus-Elsevier
Scopus-Elsevier
The development of mature granulocytes from hematopoietic precursor cells is controlled by a myriad of transcription factors which regulate the expression of essential genes, including those encoding growth factors and their receptors, enzymes, adhes
Autor:
K A, Thornton, A R, Chen, M M, Trucco, P, Shah, B A, Wilky, N, Gul, M A, Carrera-Haro, M Fogle, Ferreira, U, Shafique, J D, Powell, C F, Meyer, D M, Loeb
Publikováno v:
International journal of cancer. 133(4)
There are few effective therapies for high-risk sarcomas. Initial chemosensitivity is often followed by relapse. In vitro, mammalian target of rapamycin (mTOR) inhibition potentiates the efficacy of chemotherapy on resistant sarcoma cells. Although s
Autor:
E, Evron, C B, Umbricht, D, Korz, V, Raman, D M, Loeb, B, Niranjan, L, Buluwela, S A, Weitzman, J, Marks, S, Sukumar
Publikováno v:
Cancer research. 61(6)
Cyclin D2 is a member of the D-type cyclins, implicated in cell cycle regulation, differentiation, and malignant transformation. It was noted previously that cyclin D2 is not expressed in the majority of breast cancer cell lines, whereas abundant exp
Autor:
D M, Loeb, E, Evron, C B, Patel, P M, Sharma, B, Niranjan, L, Buluwela, S A, Weitzman, D, Korz, S, Sukumar
Publikováno v:
Cancer research. 61(3)
We analyzed Wilms' tumor suppressor 1 (WT1) expression and its regulation by promoter methylation in a panel of normal breast epithelial samples and primary carcinomas. Contrary to previous reports, WT1 protein was strongly expressed in primary carci
Publikováno v:
The Journal of biological chemistry. 269(12)
We analyzed the function of Trk nerve growth factor (NGF) receptors containing a point mutation (Tyr--Phe) in a major autophosphorylation site (Tyr-785). Tyr-785 is required for phospholipase C-gamma 1 to interact with Trk and to become tyrosine-phos
Publikováno v:
Scopus-Elsevier
A difference in affinity for a Nonidet P-40-insoluble cellular matrix was observed between the products of the viral and cellular src genes. It has previously been demonstrated that pp60v-src is associated with a detergent-insoluble matrix containing