Zobrazeno 1 - 10
of 24
pro vyhledávání: '"D M, Fast"'
Publikováno v:
Journal of mass spectrometry : JMS. 35(3)
A flow injection/tandem mass spectrometric assay was developed to quantitate SC-68328 in dog plasma using its stable isotopic analog [13C4]SC-68328 as an internal standard (IS). Since SC-68328, a manganese-based superoxide dismutase mimetic, is very
Autor:
S K, Paulson, T A, Kaprak, C J, Gresk, D M, Fast, M T, Baratta, E G, Burton, A P, Breau, A, Karim
Publikováno v:
Biopharmaceuticsdrug disposition. 20(6)
The plasma protein binding of celecoxib was determined for animals and humans using in vitro and ex vivo methods. Eight, healthy, human volunteers (three male, five female, 20-39 years) received celecoxib (600 mg) BID for 7 days, blood samples were c
Publikováno v:
Clinical Chemistry. 26:480-486
We conducted a voluntary survey of laboratories and manufacturers to assess the current quality of analytical assays for serum digoxin. More than 300 clinical laboratories and 18 manufacturers responded, giving data on methods, instruments, computati
Publikováno v:
Clinical Chemistry. 26:1156-1164
Publikováno v:
Clinical Chemistry. 29:793-799
We conducted a five-component, five-level response-surface experiment to optimize the pH and the concentrations of magnesium, creatine phosphate, adenosine diphosphate, and buffer in an assay for creatine kinase. Under optimal conditions, creatine ki
Autor:
Eric J. Sampson, S S McKneally, P H Duncan, D M Fast, D D Bayse, M A Baird, M L MacNeil, V S Whitner
Publikováno v:
Clinical Chemistry. 27:714-720
We describe the preparation and characterization of materials containing human pancreatic and salivary alpha-amylase (EC 3.2.1.1) and examine their relationship to endogenous amylase in human serum. Amylase was purified from human pancreas and saliva
Publikováno v:
Journal of Clinical Microbiology. 25:1201-1206
Conditions are described for the detection of tuberculostearic acid (10-methyloctadecanoate; C18 X CH3) in cerebrospinal fluid and serum of patients with tuberculous meningitis. C18 X CH3 was found in both the cerebrospinal fluid and serum of patient
Publikováno v:
Clinical Chemistry. 30:93-97
In developing a Reference Material for alkaline phosphatase, we studied the stability, kinetic properties, and commutability of separate preparations of the purified enzyme from human liver, intestine, bone, and placenta. The Michaelis constants (Km)
Publikováno v:
Clinical Chemistry. 30:1322-1326
We examined the reaction surfaces around five variables (imidazole, ADP, creatine phosphate, magnesium, and pH) in the Scandinavian method for determining creatine kinase, using factorial experimentation (five level, five factor) at reaction temperat
Publikováno v:
Clinical Chemistry. 23:1230-1237
This paper describes the evaluation of a system for computer-controlled discrete sampling and stopped-flow mixing for equilibrium and kinetic determinations of several sorts of analytes in human serum. The instrumental system features a wash-out samp