Zobrazeno 1 - 10
of 19
pro vyhledávání: '"D M, Dorsa"'
Publikováno v:
Minerva endocrinologica. 32(2)
Estrogen is neuroprotective in a large number of models in vivo and in vitro. Its application in hormone replacement therapy has proven to be more complicated, necessitating better understanding of how estrogen signals in the brain. Estrogen binds to
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 299(1)
Genistein is a potent plant-derived isoflavone displaying estrogenic activity at low (nanomolar) concentrations and antiproliferative and antiangiogenic properties at higher concentrations (above 10-50 microM). The antiproliferative potential of geni
Publikováno v:
Endocrinology. 141(11)
Neuronal expression of vasopressin messenger RNA (mRNA) and peptide has been shown to be estrogen dependent. A 5.5-kb genomic DNA fragment, 5' of the AVP coding region, was used in luciferase reporter assays to measure transcriptional activation by e
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 291(2)
Acute blockade of dopamine D(2) receptors by the typical antipsychotic drug haloperidol leads to alterations in neuronal gene expression and behavior. In the dorsolateral striatum, the levels of mRNA for the immediate-early gene c-fos and the neurope
Publikováno v:
Progress in brain research. 119
Vasopressinergic neurotransmission is intimately linked to steroid hormone signaling. Both arginine vasopressin (VP) and the extrahypothalamic VP V1a receptors are regulated by steroid hormones. Here, we present work that has been done in our laborat
Autor:
T L, Bale, D M, Dorsa
Publikováno v:
Advances in experimental medicine and biology. 449
Publikováno v:
Brain research. Developmental brain research. 106(1-2)
Dopamine receptor expression in human fetal forebrain (between 6 and 20 weeks of gestation) was measured using tissue-slice receptor autoradiography with the D1-like and D2-like antagonists [3H]-SCH23390 and [3H]-YM09151-2, respectively. Tissue secti
Autor:
R P, Ward, D M, Dorsa
Publikováno v:
The Journal of comparative neurology. 370(3)
There are two primary output pathways from the striatum: a projection to the globus pallidus, and projection to the substantia nigra. Certain striatally expressed neuropeptides are differentially distributed between these two pathways. Specifically,
Publikováno v:
Advances in experimental medicine and biology. 395
A genomic clone was used to generate a rat oxytocin receptor (OTR) probe for in situ hybridization studies in order to monitor changes in expression of OTR mRNA in the CNS of male and female rats in brain regions reported to be rich in OTR binding. T
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 271(1)
Previous studies have shown elevation of neurotensin neuromedin N (NT/N) and c-fos mRNA in the dorsolateral region of the rat neostriatum (DLSt) by acute administration of only typical antipsychotic drugs. However, NT/N mRNA in the nucleus accumbens-