Zobrazeno 1 - 10
of 102
pro vyhledávání: '"D Linnekin"'
Publikováno v:
Blood. 80:3070-3078
The erythropoietin receptor (EPO-R) can be activated to signal cell growth by binding either EPO or gp55, the Friend spleen focus-forming virus (SFFV) glycoprotein. EPO binding induces tyrosine kinase activity and rapid tyrosine phosphorylation of se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbbcb0ac53c10fffbfe3fb86ae4bab63
https://doi.org/10.1182/blood.v80.12.3070.3070
https://doi.org/10.1182/blood.v80.12.3070.3070
Autor:
P A, Tilbrook, G A, Palmer, T, Bittorf, D J, McCarthy, M J, Wright, M K, Sarna, D, Linnekin, V S, Cull, J H, Williams, E, Ingley, J, Schneider-Mergener, G, Krystal, S P, Klinken
Publikováno v:
Cancer research. 61(6)
This study examined the impact of the tyrosine kinase Lyn on erythropoietin-induced intracellular signaling in erythroid cells. In J2E erythroleukemic cells, Lyn coimmunoprecipitated with numerous proteins, including SHP-1, SHP-2, ras-GTPase-activati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59e10bbe004b41bdf59774687f790a8c
https://pubmed.ncbi.nlm.nih.gov/11289114
https://pubmed.ncbi.nlm.nih.gov/11289114
Publikováno v:
Blood. 94(6)
Stem cell factor (SCF) exerts its biological effects by binding to a specific receptor, the tyrosine kinase c-Kit, which is expressed on the cell surface. Although normal cellular trafficking of growth factor receptors may play a critical role in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27b8d42ae7d2b4859a91c047c481a7fa
https://pubmed.ncbi.nlm.nih.gov/10477727
https://pubmed.ncbi.nlm.nih.gov/10477727
Publikováno v:
Cancer research. 58(20)
At least 70% of small cell lung cancers (SCLCs) express the Kit receptor tyrosine kinase and its ligand, stem cell factor (SCF). In an effort to define the signal transduction pathways activated by Kit in SCLC, we focused on Src family kinases and, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::925c3d4ec81c0300bc5893108fbd0caf
https://pubmed.ncbi.nlm.nih.gov/9788619
https://pubmed.ncbi.nlm.nih.gov/9788619
Autor:
S R, Weiler, S, Mou, C S, DeBerry, J R, Keller, F W, Ruscetti, D K, Ferris, D L, Longo, D, Linnekin
Publikováno v:
Blood. 87(9)
Stem cell factor (SCF) is a hematopoietic growth factor that interacts with the receptor tyrosine kinase, c-kit. We have found that SCF-stimulates rapid and transient tyrosine phosphorylation of JAK2 in human and murine cell lines, as well as in norm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5dce92079cfeea6d17bb599f2945ad0
https://pubmed.ncbi.nlm.nih.gov/8611693
https://pubmed.ncbi.nlm.nih.gov/8611693
Publikováno v:
Blood. 84(1)
The human myeloid cell line HL-60 expresses approximately 300 high-affinity granulocyte-macrophage colony-stimulating factor receptors (GM-CSFRs), yet treatment of these cells with GM-CSF does not result in enhanced cellular proliferation or increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b253eb87c9eeab4ae153d06cfec8aa6f
https://pubmed.ncbi.nlm.nih.gov/8018933
https://pubmed.ncbi.nlm.nih.gov/8018933
Publikováno v:
Blood. 80(12)
The erythropoietin receptor (EPO-R) can be activated to signal cell growth by binding either EPO or gp55, the Friend spleen focus-forming virus (SFFV) glycoprotein. EPO binding induces tyrosine kinase activity and rapid tyrosine phosphorylation of se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7200a753ee42806161e98a489c588e6e
https://pubmed.ncbi.nlm.nih.gov/1467516
https://pubmed.ncbi.nlm.nih.gov/1467516
Publikováno v:
The Journal of biological chemistry. 267(33)
We have examined the signal transduction pathways of a number of cytokines that interact with receptors that are members of the hematopoietin receptor superfamily. A 97-kDa protein was phosphorylated on tyrosine in response to stimulation of appropri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2fa6d55e6f1fadebda2f6e4b0a7a4ed3
https://pubmed.ncbi.nlm.nih.gov/1385430
https://pubmed.ncbi.nlm.nih.gov/1385430
Publikováno v:
Blood. 80(8)
We have examined the relationship between granulocyte-macrophage colony- stimulating factor (GM-CSF) and interleukin-3 (IL-3) receptor expression and signal transduction in populations of HL-60 cells differing in proliferative capacity to these cytok
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64d7408d2c6f4518f2784df658abd754
https://pubmed.ncbi.nlm.nih.gov/1382709
https://pubmed.ncbi.nlm.nih.gov/1382709
Publikováno v:
The Journal of biological chemistry. 267(15)
The intracellular events which are involved in controlling the G1 to S phase transition during the eucaryotic cell cycle are important to define in order to understand the mechanisms by which mitogenic and growth arrest-inducing agents control cell g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dfded4e967303f0553ab440d2c5be049
https://pubmed.ncbi.nlm.nih.gov/1534085
https://pubmed.ncbi.nlm.nih.gov/1534085