Whole genome association analysis of treatment response in obsessive-compulsive disorder

Autor: Manuel Mattheisen, Oscar J. Bienvenu, Youfa Wang, James A. Knowles, Yin Yao Shugart, Kathleen D. Askland, John Piacentini, Erika L. Nurmi, Fernando S. Goes, Daniel A. Geller, Abby J. Fyer, Ann E. Pulver, Brion S. Maher, Christoph Lange, Benjamin D. Greenberg, Nicole C.R. McLaughlin, Gerald Nestadt, Jack Samuels, D. L. Murphy, Yun Zhu, Hai-De Qin, Kung-Yee Liang, Marco A. Grados, James T. McCracken, David Valle, S. A. Rasmussen, Mark A. Riddle, S. E. Stewart, Bernadette Cullen, David L. Pauls

Publikováno v: Molecular psychiatry
Qin, H, Samuels, J F, Wang, Y, Zhu, Y, Grados, M A, Riddle, M A, Greenberg, B D, Knowles, J A, Fyer, A J, McCracken, J T, Murphy, D L, Rasmussen, S A, Cullen, B A, Piacentini, J, Geller, D, Stewart, S E, Pauls, D, Bienvenu, O J, Goes, F S, Maher, B, Pulver, A E, Valle, D, Mattheisen, M, McLaughlin, N C, Liang, K-Y, Nurmi, E L, Askland, K D, Nestadt, G & Shugart, Y Y 2015, ' Whole-genome association analysis of treatment response in obsessive-compulsive disorder ', Molecular Psychiatry . https://doi.org/10.1038/mp.2015.32

Up to 30% of patients with obsessive-compulsive disorder (OCD) exhibit an inadequate response to serotonin reuptake inhibitors (SRIs). To date, genetic predictors of OCD treatment response have not been systematically investigated using genome-wide a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc046cecc569ae35de6ee1f0f7ae485
http://europepmc.org/articles/PMC5027902

Genome-wide association study of obsessive-compulsive disorder

Autor: Helena Garrido, Richard O'Brien, Michael H. Bloch, David L. Pauls, M. Van Der Brug, Anna Tikhomirov, Andrew B. Singleton, Susanne Walitza, Benjamin M. Neale, Patrick Evans, Rianne M. Blom, Mina Ryten, James L. Kennedy, Christopher Pittenger, C. Illman, Amin Azzam, Stephen A. Haddad, Gregory L. Hanna, Michele T. Pato, D. Rosenberg, Maurizio Turiel, Stephan Ruhrmann, Peter Falkai, Nuria Lanzagorta, Richard Delorme, D. G. Hernandez, Leonhard Lennertz, Abby J. Fyer, M Conceição do Rosário, Euripedes Constantino Miguel, John Hardy, Carlos N. Pato, Francesca Frau, Hans-Jörgen Grabe, Daniele Cusi, Alan B. Zonderman, Dieter Deforce, Peter Heutink, Brooke Sheppard, Jacquelyn Crane, Dongmei Yu, Danielle C. Cath, Rainald Moessner, Nancy J. Cox, Shaun Purcell, James A. Knowles, Daniel B. Mirel, Aline S. Sampaio, D. L. Murphy, R. Johnson, Jens R. Wendland, David V. Conti, Carolina Cappi, Paula Umaña, Marco A. Grados, Dan J. Stein, J. R. Gibbs, Humberto Nicolini, Anna Pluzhnikov, Denise A. Chavira, F. Van Nieuwerburgh, Valsamma Eapen, Lisa Osiecki, Christine Lochner, Juan C. Troncoso, Jeremy Veenstra-VanderWeele, Mark A. Riddle, Michael Wagner, Jeremiah M. Scharf, Beatriz Camarena, Edwin H. Cook, Ana Gabriela Hounie, Daniah Trabzuni, Donald W. Black, Scott L. Rauch, Marion Leboyer, Andrew Crenshaw, S. E. Stewart, Roel A. Ophoff, Dianne M. Hezel, Damiaan Denys, Gerald Nestadt, Melissa Parkin, Karin Egberts, Colin Smith, Anuar Konkashbaev, Danielle Posthuma, Vladimir Coric, James F. Leckman, Eric Strengman, Jack Samuels, Tobias J. Renner, Michael E. Weale, L. Ferrucci, Mark R. Cookson, Laura Bellodi, Oscar J. Bienvenu, C. Mayerfeld, Christopher K. Edlund, Youfa Wang, Robert Walker, Dan L. Longo, Maria Cristina Cavallini, James T. McCracken, Jesen Fagerness, H. R. Zielke, Homero Vallada, Chunyu Liu, Bernadette Cullen, Carol A. Mathews, Sian M. J. Hemmings, Allissa Dillman, E. Voyiaziakis, Fabio Macciardi, Eduardo Fournier, Benjamin D. Greenberg, Eric R. Gamazon, S. Arepalli, Margaret A. Richter, Bryan J. Traynor, Michael A. Jenike, J.H. Smit, M. A. Nalls, Lauren M. McGrath, Paul D. Arnold, H.G.M. Westenberg, W. Maier

Publikováno v: MOLECULAR PSYCHIATRY
Molecular psychiatry, 18(7), 788-798. Nature Publishing Group
Stewart, S E, Yu, D, Scharf, J M, Neale, B M, Fagerness, J A, Mathews, C A, Arnold, P D, Evans, P D, Gamazon, E R, Davis, L K, Osiecki, L, McGrath, L, Haddad, S, Crane, J, Hezel, D, Illmann, C, Mayerfeld, C, Konkashbaev, A I, Liu, C, Pluzhnikov, A, Tikhomirov, A, Edlund, C K, Rauch, S L, Moessner, R, Falkai, P, Maier, W, Ruhrmann, S, Grabe, H J, Lennertz, L, Wagner, M, Bellodi, L, Cavallini, M C, Richter, M A, Cook, E H, Kennedy, J L, Rosenberg, D, Stein, D J, Hemmings, S M, Lochner, C, Azzam, A, Chavira, D A, Fournier, E, Garrido, H, Sheppard, B, Umaña, P, Murphy, D L, Wendland, J R, Veenstra-Vanderweele, J, Denys, D, Blom, R, Deforce, D, van Nieuwerburgh, F, Westenberg, H G, Walitza, S, Egberts, K, Renner, T, Miguel, E C, Cappi, C, Hounie, A G, Conceição do Rosário, M, Sampaio, A S, Vallada, H, Nicolini, H, Lanzagorta, N, Camarena, B, Delorme, R, Leboyer, M, Pato, C N, Pato, M T, Voyiaziakis, E, Heutink, P, Cath, D C, Posthuma, D, Smit, J H, Samuels, J, Bienvenu, O J, Cullen, B, Fyer, A J, Grados, M A, Greenberg, B D, McCracken, J T, Riddle, M A, Wang, Y, Coric, V, Leckman, J F, Bloch, M, Pittenger, C, Eapen, V, Black, D W, Ophoff, R A, Strengman, E, Cusi, D, Turiel, M, Frau, F, Macciardi, F, Gibbs, J R, Cookson, M R, Singleton, A, Hardy, J, Crenshaw, A T, Parkin, M A, Mirel, D B, Conti, D V, Purcell, S, Nestadt, G, Hanna, G L, Jenike, M A, Knowles, J A, Cox, N & Pauls, D L 2013, ' Genome-wide association study of obsessive-compulsive disorder ', Molecular Psychiatry, vol. 18, no. 7, pp. 788-798 . https://doi.org/10.1038/mp.2012.85
Molecular Psychiatry, 18(7), 788-798. Nature Publishing Group
Molecular Psychiatry, 18, 788-798. Nature Publishing Group

Obsessive-compulsive disorder (OCD) is a common, debilitating neuropsychiatric illness with complex genetic etiology. The International OCD Foundation Genetics Collaborative (IOCDF-GC) is a multi-national collaboration established to discover the gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b0ea4362a0a0cf0fa3ba59bed2e249
https://doi.org/10.1038/mp.2012.85

Cocaine-conditioned locomotion in dopamine transporter, norepinephrine transporter and 5-HT transporter knockout mice

Autor: George R. Uhl, Ichiro Sora, Xiao Fei Li, F.S. Hall, Marc G. Caron, D. L. Murphy, K.P. Lesch, J. Randall-Thompson

Publikováno v: Neuroscience. 162:870-880

The behavioral effects of cocaine are affected by gene knockout (KO) of the dopamine transporter (DAT), the serotonin transporter (SERT) and the norepinephrine transporter (NET). The relative involvement of each of these transporters varies depending

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::279542528b40628903731216ca6c18ec
https://doi.org/10.1016/j.neuroscience.2009.05.058

Clinical and Laboratory Studies with Selective Monoamine-Oxidase-Inhibiting Drugs

Autor: F. Karoum, N. A. Garrick, Larry J. Siever, D. L. Murphy, Robert M. Cohen, Benjamin F. Roy, Markku Linnoila, Richard Jed Wyatt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d92426f764b35f0257f887fa68a0b41
https://doi.org/10.1159/000407526

Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS

Autor: Abby J. Fyer, Jack Samuels, Benjamin D. Greenberg, David L. Pauls, Kung-Yee Liang, Ann E. Pulver, Kathleen D. Askland, Hai-De Qin, Yin Yao Shugart, Daniel A. Geller, Erika L. Nurmi, D. L. Murphy, Fernando S. Goes, Nicole C.R. McLaughlin, Mark A. Riddle, David Valle, S. A. Rasmussen, James T. McCracken, Yuchuan Wang, Brion S. Maher, Marco A. Grados, S. E. Stewart, Christoph Lange, Bernadette Cullen, John Piacentini, James A. Knowles, Manuel Mattheisen, Oscar J. Bienvenu, Gerald Nestadt

Publikováno v: Molecular psychiatry, vol 20, iss 3
Molecular psychiatry
Mattheisen, M, Samuels, J F, Wang, Y, Greenberg, B D, Fyer, A J, McCracken, J T, Geller, D A, Murphy, D L, Knowles, J A, Grados, M A, Riddle, M A, Rasmussen, S A, McLaughlin, N C, Nurmi, E L, Askland, K D, Qin, H-D, Cullen, B A, Piacentini, J, Pauls, D L, Bienvenu, O J, Stewart, S E, Liang, K-Y, Goes, F S, Maher, B, Pulver, A E, Shugart, Y Y, Valle, D, Lange, C & Nestadt, G 2014, ' Genome-wide association study in obsessive-compulsive disorder : results from the OCGAS ', Molecular Psychiatry . https://doi.org/10.1038/mp.2014.43

Obsessive-compulsive disorder (OCD) is a psychiatric condition characterized by intrusive thoughts and urges and repetitive, intentional behaviors that cause significant distress and impair functioning. The OCD Collaborative Genetics Association Stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d63aad2357ff1d3cbb11a6f8eae247b
https://escholarship.org/uc/item/4bs5k6qh