Zobrazeno 1 - 9
of 9
pro vyhledávání: '"D L Jankovic"'
Autor:
M C Kullberg, J A Berzofsky, D L Jankovic, S Barbieri, M E Williams, P Perlmann, A Sher, M Troye-Blomberg
Publikováno v:
The Journal of Immunology. 156:1482-1489
We describe a novel amplification mechanism underlying the increased early IL-4 production observed in Schistosoma mansoni-infected mice in response to a non-parasite Ag, sperm whale myoglobin (SwMb). Earlier studies have shown that splenic Fc epsilo
Publikováno v:
The Journal of Immunology. 148:3820-3829
We have analyzed the evolution of the pattern of lymphokine secretion by Th cell lines specific for either the synthetic terpolymer Glu60Ala30Tyr10 (GAT) or killed bacillus Calmette Guérin. When cultured in the presence of exogenous rIL-2 as a growt
Publikováno v:
The Journal of Immunology. 147:2970-2977
Using a cell-free translation system we have expressed the Mr 55,000 subunit of the murine IL-2R (p55 IL-2R), which binds IL-2 with low affinity (Kd = 10 nM). Mutants and truncated forms of p55 IL-2R have been used to map the epitopes recognized by t
Publikováno v:
The Journal of Immunology. 145:4136-4144
An IL-4-dependent T cell clone (LD8) was isolated from the murine IL-2-dependent cytotoxic T cell line C30.1. This clone has lost the capacity to proliferate in response to IL-2 after long-term culture in IL-4. LD8 cells express the p70, but not the
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 147(9)
Using a cell-free translation system we have expressed the Mr 55,000 subunit of the murine IL-2R (p55 IL-2R), which binds IL-2 with low affinity (Kd = 10 nM). Mutants and truncated forms of p55 IL-2R have been used to map the epitopes recognized by t
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 145(12)
An IL-4-dependent T cell clone (LD8) was isolated from the murine IL-2-dependent cytotoxic T cell line C30.1. This clone has lost the capacity to proliferate in response to IL-2 after long-term culture in IL-4. LD8 cells express the p70, but not the
Publikováno v:
The Journal of Experimental Medicine
Aged killer (AK) T cells are antigen-independent, IL-2-requiring variants of antigen-dependent CTL clones that have lost their original antigen specificity and have acquired, instead, specific cytotoxicity for P815 target cells. In this report we stu
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 142(9)
We have investigated the effects of IL-2 and IL-4 on different parameters of T cell activation using three T cell lines. The Th cell line L14 and the cytotoxic T cell line C30.1, both grown in IL-2-containing medium, and a line derived from C30.1 cel
Autor:
G. McMASTER, Jörg T. Epplen, D. L. Jankovic, Klaus Eichmann, Hans Ulrich Weltzien, D. Woodland
Publikováno v:
Scandinavian journal of immunology. 25(2)
In this paper we demonstrate that the generation of cytotoxic T-cell hybridomas (CTH) that retain classically H-2 restricted and antigen-specific lytic activity is not generally feasible by fusion of cytotoxic T cells (CTL) with the AKR thymoma BW514