Zobrazeno 1 - 10
of 47
pro vyhledávání: '"D L Earnest"'
Publikováno v:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 21(11)
Increased cholinergic stimulation and accelerated gastrointestinal (GI) transit may be produced by direct stimulation of the acetylcholine (ACh) receptor with an appropriate agonist by increased release of ACh from cholinergic nerve terminals or by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c241019bedf994a1ead7fc8bb38d674
https://pubmed.ncbi.nlm.nih.gov/19210632
https://pubmed.ncbi.nlm.nih.gov/19210632
Autor:
G, Tougas, W J, Snape, M H, Otten, D L, Earnest, K-E, Langaker, R E, Pruitt, E, Pecher, B, Nault, M A, Rojavin
Publikováno v:
Alimentary pharmacologytherapeutics. 16(10)
Tegaserod is a 5-hydroxytryptamine-4 receptor partial agonist. Oral administration causes gastrointestinal effects resulting in increased gastrointestinal motility and attenuation of visceral sensation.: To determine the long-term safety and tolerabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b77f99b44aecd8f269ac04032d767809
https://pubmed.ncbi.nlm.nih.gov/12269961
https://pubmed.ncbi.nlm.nih.gov/12269961
Autor:
R, Calaluce, D L, Earnest, D, Heddens, J G, Einspahr, D, Roe, C L, Bogert, J R, Marshall, D S, Alberts
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 9(12)
Prostaglandin E2 (PGE2) has served as a surrogate end point biomarker in colorectal tumor progression. Colonic mucosa PGE2 levels of patients with colorectal adenomas or carcinomas have been shown to be higher than in control subjects. Our dose-findi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2cf9b32caf6b0e7974d7d2421efd4ce
https://pubmed.ncbi.nlm.nih.gov/11142413
https://pubmed.ncbi.nlm.nih.gov/11142413
Autor:
H H, Chow, D L, Earnest, D, Clark, N, Mason-Liddil, C B, Kramer, J G, Einspahr, J M, Guillen-Rodriguez, D J, Roe, W, Malone, J A, Crowell, D S, Alberts
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 9(4)
Nonsteroidal antiinflammatory drugs are among the most promising chemopreventive agents for colorectal cancer. Although the mechanism by which nonsteroidal antiinflammatory drugs exert such effects remains to be further characterized, their best know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2301cbbe815790905439c17c12dc2f75
https://pubmed.ncbi.nlm.nih.gov/10794478
https://pubmed.ncbi.nlm.nih.gov/10794478
Autor:
D S, Alberts, M E, Martínez, D J, Roe, J M, Guillén-Rodríguez, J R, Marshall, J B, van Leeuwen, M E, Reid, C, Ritenbaugh, P A, Vargas, A B, Bhattacharyya, D L, Earnest, R E, Sampliner
Publikováno v:
The New England journal of medicine. 342(16)
The risks of colorectal cancer and adenoma, the precursor lesion, are believed to be influenced by dietary factors. Epidemiologic evidence that cereal fiber protects against colorectal cancer is equivocal. We conducted a randomized trial to determine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0038c7a2542a6b3b902ebf0335d5e79
https://pubmed.ncbi.nlm.nih.gov/10979771
https://pubmed.ncbi.nlm.nih.gov/10979771
Publikováno v:
Cancer research. 58(8)
We recently showed that feeding the cytoprotective bile acid ursodeoxycholic acid (UDCA) to rats resulted in significant reduction in polyps and especially cancers, both in number and size (D. L. Earnest et al., Cancer Res., 54: 5071-5074, 1994). Bec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ccad54038a05b5cc4eaf6555e837d63
https://pubmed.ncbi.nlm.nih.gov/9563483
https://pubmed.ncbi.nlm.nih.gov/9563483
Publikováno v:
The American journal of gastroenterology. 92(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b57dee3db5db74a905d546c02573eb4b
https://pubmed.ncbi.nlm.nih.gov/9040226
https://pubmed.ncbi.nlm.nih.gov/9040226
Autor:
R K, Wali, B P, Frawley, S, Hartmann, H K, Roy, S, Khare, B A, Scaglione-Sewell, D L, Earnest, M D, Sitrin, T A, Brasitus, M, Bissonnette
Publikováno v:
Cancer research. 55(22)
Several lines of evidence from our laboratory and others indicate that epigenetic alterations in protein kinase C (PKC) are involved in colonic carcinogenesis in both man and experimental animals. Furthermore, bile salts, known activators of PKC, hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::897d2f49668c074bbfd17d7ca70a6869
https://pubmed.ncbi.nlm.nih.gov/7585585
https://pubmed.ncbi.nlm.nih.gov/7585585
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 4(3)
It has been demonstrated and confirmed that certain nonsteroidal anti-inflammatory drugs which inhibit cyclooxygenase and the synthesis of prostaglandins and other eicosanoids, can reduce the formation of both colon polyps and cancers in experimental
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f58d15bd66fa0e0786b93281343e4cab
https://pubmed.ncbi.nlm.nih.gov/7606198
https://pubmed.ncbi.nlm.nih.gov/7606198
Autor:
D L, Earnest, H, Holubec, R K, Wali, C S, Jolley, M, Bissonette, A K, Bhattacharyya, H, Roy, S, Khare, T A, Brasitus
Publikováno v:
Cancer research. 54(19)
The present studies were conducted at the Universities of Chicago and Arizona to examine and compare the effects of supplemental dietary ursodeoxycholic acid to cholic acid, a known tumor promoter, and to piroxicam, a known chemopreventive agent, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::642236d1d9407b0302d235818856df29
https://pubmed.ncbi.nlm.nih.gov/7923119
https://pubmed.ncbi.nlm.nih.gov/7923119