Zobrazeno 1 - 10
of 18
pro vyhledávání: '"D L Crimmins"'
Publikováno v:
Journal of the American Society of Nephrology. 8:1276-1282
Hyperglycemia directly contributes to the development of diabetic nephropathy. A high-serum glucose concentration alters intraglomerular hemodynamics and promotes deposition of extracellular matrix in the kidney. Nitric oxide (NO) is a short-lived me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6280c24b51b68f2540cee6a7028466
https://doi.org/10.1681/asn.v881276
https://doi.org/10.1681/asn.v881276
Publikováno v:
Molecular and Cellular Biology. 13:7418-7428
IRS-1 (insulin receptor substrate 1) is a principal insulin receptor substrate that undergoes tyrosine phosphorylation during insulin stimulation. It contains over 20 potential tyrosine phosphorylation sites, and we suspect that multiple insulin sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0047826940f2269af09e087599ba3c5e
https://doi.org/10.1128/mcb.13.12.7418
https://doi.org/10.1128/mcb.13.12.7418
Autor:
David B. Sacks, Martin G. Myers, R S Thoma, D L Crimmins, Morris F. White, Milenko J. Tanasijevic
Publikováno v:
Journal of Biological Chemistry. 268:18157-18166
IRS-1, a principal substrate of the insulin receptor, is phosphorylated on serine, threonine, and tyrosine residues in a variety of tissues during insulin stimulation. Casein kinase II, an insulin-sensitive serine/threonine kinase, catalyzed the in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c65968b61d17050c3f260868048ca330
https://doi.org/10.1016/s0021-9258(17)46824-4
https://doi.org/10.1016/s0021-9258(17)46824-4
Publikováno v:
Infection and Immunity. 59:1285-1289
PspA is an antigenically variable surface protein of Streptococcus pneumoniae that appears to be essential for full pneumococcal virulence. In addition, monoclonal antibodies to PspA protect mice against infection with specific strains of pneumococci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::674d0249a8a16b637e5a246d70903245
https://doi.org/10.1128/iai.59.4.1285-1289.1991
https://doi.org/10.1128/iai.59.4.1285-1289.1991
Autor:
M, Krych-Goldberg, R E, Hauhart, V B, Subramanian, B M, Yurcisin, D L, Crimmins, D E, Hourcade, J P, Atkinson
Publikováno v:
The Journal of biological chemistry. 274(44)
The goal of this study was to identify the site(s) in CR1 that mediate the dissociation of the C3 and C5 convertases. To that end, truncated derivatives of CR1 whose extracellular part is composed of 30 tandem repeating modules, termed complement con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d7befbe14af942be0f10974302be1b2
https://pubmed.ncbi.nlm.nih.gov/10531307
https://pubmed.ncbi.nlm.nih.gov/10531307
Publikováno v:
Clinical chemistry. 44(6 Pt 1)
Irreversible glycation of the hemoglobin A0 (HbA0) beta chain leads to the production of HbA1C, which can be used to monitor long-term blood glucose control in patients with diabetes mellitus. HbA1C is less positively charged than nonglycated HbA0, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29bb59ab6041ba2e16d38b371c169291
https://pubmed.ncbi.nlm.nih.gov/9625056
https://pubmed.ncbi.nlm.nih.gov/9625056
Publikováno v:
Clinical chemistry. 43(3)
P-glycoprotein (Pgp) is a 170-kDa membrane transporter that mediates drug efflux and is an effector of multidrug resistance. SDZ PSC 833 (PSC), a nonimmunosuppressive cyclosporine that potently modulates Pgp, is currently under clinical evaluation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6398ffcfc07843ff72cf3b563a4a79f7
https://pubmed.ncbi.nlm.nih.gov/9068595
https://pubmed.ncbi.nlm.nih.gov/9068595
Publikováno v:
The Journal of biological chemistry. 269(9)
The hemostatic functions of human von Willebrand Factor (vWF) depend on the normal assembly of disulfide-linked multimers from approximately 250-kDa subunits. Subunits initially form dimers through disulfide bonds near the COOH terminus. Dimers then
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e03549eca714ed910562cfd7433d364d
https://pubmed.ncbi.nlm.nih.gov/8120035
https://pubmed.ncbi.nlm.nih.gov/8120035
Autor:
D L, Crimmins
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::41034d16169644c26e2c2e0a466c28d0
https://pubmed.ncbi.nlm.nih.gov/7697115
https://pubmed.ncbi.nlm.nih.gov/7697115
Autor:
M G, Scott, D L, Crimmins, D W, McCourt, G, Chung, K F, Schäble, R, Thiebe, E M, Quenzel, H G, Zachau, M H, Nahm
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 147(11)
We previously demonstrated that the human anti-Haemophilus influenzae type b polysaccharide (Hib-PS) VL repertoire is dominated by a product of the V kappa II gene, A2, and that V kappa II-A2 anti-Hib-PS antibodies have little or no somatic mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c44aa9b4d2aa2d8afc76857ed4addff
https://pubmed.ncbi.nlm.nih.gov/1940382
https://pubmed.ncbi.nlm.nih.gov/1940382