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Properties of receptor-controlled inositol trisphosphate formation in parotid acinar cells

Autor: D L Aub, J W Putney

Publikováno v: Biochemical Journal. 225:263-266

Activation of muscarinic receptors in rat parotid cells results in breakdown of polyphosphoinositides liberating inositol phosphates, including inositol trisphosphate. Formation of inositol trisphosphate appears independent of agonist-induced Ca2+ mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587fd7d61dc6467b19a4888794e7dbdd
https://doi.org/10.1042/bj2250263

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Coupling of the thyrotropin-releasing hormone receptor to phospholipase C by a GTP-binding protein distinct from the inhibitory or stimulatory GTP-binding protein

Autor: T E Cote, D L Aub, E A Frey, R D Sekura

Publikováno v: Journal of Biological Chemistry. 261:9333-9340

Thyrotropin-releasing hormone (TRH) stimulated a rapid rise in inositol trisphosphate (IP3) formation and prolactin release from 7315c tumor cells. The potencies (half-maximal) of TRH in stimulating IP3 formation and prolactin release were 100 +/- 30

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e1d6dd31995bc1b252f4d31405063cfb
https://doi.org/10.1016/s0021-9258(18)67659-8

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Regulation of thyrotropin-releasing hormone receptor binding and phospholipase C activation by a single GTP-binding protein

Autor: M E Gosse, D L Aub, T E Cote

Publikováno v: Journal of Biological Chemistry. 262:9521-9528

In a crude membrane preparation of rat 7315c cells, GTP was found to enhance thyrotropin-releasing hormone- (TRH) stimulated inositol triphosphate (IP3) formation with a potency of 0.97 +/- 0.1 microM. TRH stimulation of IP3 formation was inhibited b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::817b638550ed268e1b0052e1266a8f8e
https://doi.org/10.1016/s0021-9258(18)47964-1

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Nature of the receptor-regulated calcium pool in the rat parotid gland

Autor: James W. Putney, D L Aub, J S McKinney

Publikováno v: The Journal of Physiology. 331:557-565

1. The transient release of 86Rb from parotid slices induced by secretagogues was investigated. 2. In the absence of external Ca, only one transient response (to carbachol) could be obtained. 3. After blocking the cholinergic stimulus with atropine,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7b2161a58684185731265b0145e1d82
https://doi.org/10.1113/jphysiol.1982.sp014391

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Phorbol ester-induced protein secretion in rat parotid gland. Relationship to the role of inositol lipid breakdown and protein kinase C activation in stimulus-secretion coupling

Autor: J W, Putney, J S, McKinney, D L, Aub, B A, Leslie

Publikováno v: Molecular pharmacology. 26(2)

When added to rat parotid gland slices incubated in vitro, 4 alpha-phorbol-dibutyrate (PDBu) induced a dose-dependent increase in protein secretion, but did not affect membrane permeability to K+ (as determined by 86Rb efflux). The response to PDBu w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3fc232bc3e5498210c8ac55c24ed9231
https://pubmed.ncbi.nlm.nih.gov/6237255

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Messages of the Phosphoinositide Effect

Autor: G. M. Burgess, J. W. PutneyJr., D. L. Aub, P. P. Godfrey

Publikováno v: Inositol and Phosphoinositides ISBN: 9781461296027

In rat parotid acinar cells, Ca-mobilizing agonists cause a fall in cellular content of inositol lipids and an increase in diacylglycerol (DG) and soluble inositol phosphates (IPs). Kinetic analysis of the formation of IPs in parotid cells stimulated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7dc3af8cde9ca33be5444f6826ba415a
https://doi.org/10.1007/978-1-4612-5184-2_22

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Regulation of thyrotropin-releasing hormone receptor binding and phospholipase C activation by a single GTP-binding protein

Autor: D L, Aub, M E, Gosse, T E, Cote

Publikováno v: The Journal of biological chemistry. 262(20)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a535ce284efca67c61421e5cf1338cd8
https://pubmed.ncbi.nlm.nih.gov/3036863

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Coupling of the thyrotropin-releasing hormone receptor to phospholipase C by a GTP-binding protein distinct from the inhibitory or stimulatory GTP-binding protein

Autor: D L, Aub, E A, Frey, R D, Sekura, T E, Cote

Publikováno v: The Journal of biological chemistry. 261(20)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::85ba98d6c90cc0a2cbae907c470330a3
https://pubmed.ncbi.nlm.nih.gov/3013886

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Formation and biological action of inositol 1,4,5-trisphosphate

Autor: J W, Putney, D L, Aub, C W, Taylor, J E, Merritt

Publikováno v: Federation proceedings. 45(11)

A wide variety of receptors appear to be coupled to a phospholipase C (EC 3.1.4.3) that hydrolyzes inositol lipids. This reaction is believed to provide a link between receptor activation and cellular Ca2+ mobilization. The mechanisms by which this o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::252fa43cea9e0a79b90a37c1bb50270d
https://pubmed.ncbi.nlm.nih.gov/3019783

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Akademický článek

A Qualitative Investigation of Teamwork in Extreme Environments.

Autor: Olenick, Jeffrey¹ (AUTHOR) jeffrey.olenick@uga.edu, Eggler, Kristen D.¹ (AUTHOR), Bowker, Jenna² (AUTHOR), Kozlowski, Steve W. J.² (AUTHOR), Chang, Chu-Hsiang (Daisy)³ (AUTHOR), Somaraju, Ajay V.³ (AUTHOR), Griffin, Daniel J.² (AUTHOR)

Publikováno v: Group & Organization Management. Sep2024, p1.

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