Zobrazeno 1 - 10
of 20
pro vyhledávání: '"D L, Saussy"'
Autor:
W T, Jackson, L L, Froelich, R J, Boyd, J P, Schrementi, D L, Saussy, R M, Schultz, J S, Sawyer, M J, Sofia, D K, Herron, T, Goodson, D W, Snyder, P A, Pechous, S M, Spaethe, C R, Roman, J H, Fleisch
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 288(1)
The in vitro actions were investigated of LY293111, a potent and selective leukotriene B4 (LTB4) receptor antagonist, on human neutrophils, human blood fractions, guinea pig lung membranes, and guinea pig parenchymal and tracheal strips. The IC50 for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::996b6f278ef8a0043be276e322cdd84a
https://pubmed.ncbi.nlm.nih.gov/9862783
https://pubmed.ncbi.nlm.nih.gov/9862783
Autor:
C. R. Roman, Michael J. Sofia, Baldwin Rf, Sandra L. Cockerham, S. A. Silbaugh, K. Nelson, Larry L. Froelich, P. Marder, Floreancig Paul Edward, Stephen Richard Baker, P. W. Stengel, Jason Scott Sawyer, S. M. Spaethe, D. L. Saussy, J. H. Fleisch, W. T. Jackson, Bach Nicholas J
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461374305
Leukotriene B4 (LTB4) has been implicated as a key pro-inflammatory mediator in human diseases such as asthma, inflammatory bowel disease, psoriasis and arthritis (1). LTB4’s role in human disease is supported by the fact that via G-protein coupled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1ac724edeb191b804e43ef5b753a2f4
https://doi.org/10.1007/978-1-4615-5325-0_51
https://doi.org/10.1007/978-1-4615-5325-0_51
Autor:
M J, Sofia, P, Floreancig, N, Bach, S R, Baker, K, Nelson, J S, Sawyer, R, Baldwin, S L, Cockerham, J H, Fleisch, L L, Froelich, W T, Jackson, P, Marder, C R, Roman, D L, Saussy, S A, Silbaugh, S M, Spaethe, P W, Stengel
Publikováno v:
Advances in experimental medicine and biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::54fe637429ecdefdf648b1dcf9b4cec6
https://pubmed.ncbi.nlm.nih.gov/9547580
https://pubmed.ncbi.nlm.nih.gov/9547580
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 278(1)
The activity of a series of busprione analogs at recombinant and rat thoracic aorta alpha-1 adrenoceptors was investigated. Compound affinity for recombinant alpha-1A, alpha-1B and alpha-1D adrenoceptors from human and animal sources was determined b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::619807996b271c043f918f3b5bb0271e
https://pubmed.ncbi.nlm.nih.gov/8764344
https://pubmed.ncbi.nlm.nih.gov/8764344
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 271(3)
Experiments were designed to characterize the predominant subtype of alpha-1 adrenoceptors in human and canine prostate tissue. The chemical (+/-)-beta-([125I]iodo-4-hydroxyphenyl)-ethyl- aminomethyl-tetralone bound in a specific, saturable manner to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81c283c0ab1932cfb881306bf4b4dabf
https://pubmed.ncbi.nlm.nih.gov/7996431
https://pubmed.ncbi.nlm.nih.gov/7996431
Autor:
Baldwin Rf, P. W. Stengel, Sandra L. Cockerham, D. L. Saussy, Larry L. Froelich, Michael J. Sofia, Floreancig Paul Edward, P. Marder, S. A. Silbaugh, Jason Scott Sawyer
Publikováno v:
Journal of medicinal chemistry. 36(24)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea2340f03f1abfab9a0bb19fcecb722f
https://pubmed.ncbi.nlm.nih.gov/8254628
https://pubmed.ncbi.nlm.nih.gov/8254628
Publikováno v:
Eicosanoids. 5(1)
The utilization of a novel radioiodinated TXA2/PGH2 receptor antagonist, ISAP (7-[(1R,2S,3S,5R)-6,6-dimethyl-3(4- iodobenzenesulfonylamino)-bicyclo[3.1.1]-hept-2-yl]-5(Z)-heptenoic acid) to characterize TXA2/PGH2 receptors from guinea pig lung parenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba40966dede4990b481ccf278ebc05fd
https://pubmed.ncbi.nlm.nih.gov/1419073
https://pubmed.ncbi.nlm.nih.gov/1419073
Publikováno v:
Advances in prostaglandin, thromboxane, and leukotriene research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::901fe1e34f45583a9df3bc4bef1802c8
https://pubmed.ncbi.nlm.nih.gov/1825567
https://pubmed.ncbi.nlm.nih.gov/1825567
Publikováno v:
Molecular pharmacology. 39(1)
Thromboxane A2 (TXA2) and prostaglandin H2 (PGH2) are potent constrictors of airway smooth muscle and may mediate some of the pulmonary effects of leukotrienes. To date, the TXA2/PGH2 receptor in lung has not been well characterized. In this report,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7beafd082cdab782b42c41f6c1b5cab8
https://pubmed.ncbi.nlm.nih.gov/1824791
https://pubmed.ncbi.nlm.nih.gov/1824791
Autor:
T A, Morinelli, M, Naka, A, Masuda, J E, Oatis, A K, Okwu, D E, Mais, D L, Saussy, P V, Halushka
Publikováno v:
Advances in prostaglandin, thromboxane, and leukotriene research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1ca984c26dfe93fad4fcefc6a8f8354
https://pubmed.ncbi.nlm.nih.gov/1825565
https://pubmed.ncbi.nlm.nih.gov/1825565