Zobrazeno 1 - 10
of 45
pro vyhledávání: '"D L, Rucknagel"'
Publikováno v:
Blood. 88:4359-4365
The K+ efflux that mediates sickle-cell dehydration may occur through several pathways, including two with a high capacity for mediating rapid K+ loss, KCl cotransport and the Ca(2+)-dependent K+ channel [K(Ca2+)]. The rate and pathway of red blood c
Autor:
D L, Rucknagel
Publikováno v:
Pediatric pathologymolecular medicine. 20(2)
The acute chest syndrome is a generic term for pulmonary complications of sickle cell diseases with heterogeneous etiologies that include pneumonia, vaso-occlusion of pulmonary arterioles, rib infarction, and fat embolism syndrome. My review summariz
Autor:
R S, Franco, Z, Yasin, J M, Lohmann, M B, Palascak, T A, Nemeth, M, Weiner, C H, Joiner, D L, Rucknagel
Publikováno v:
Blood. 96(10)
Sickle red blood cells (RBCs) become depleted of potassium, leading to dehydration and abnormally elevated cellular density. The increased sickling that results is important for both hemolysis and vasocclusion. In this study, sickle cells were subjec
Publikováno v:
American journal of hematology. 49(1)
A term infant presented with mild cyanosis without evidence of hypoxia. Cardiopulmonary disease, polycythemia, and methemoglobinemia were excluded. Standard hemoglobin electrophoresis, including isoelectric focusing, were normal. However, by reverse-
Publikováno v:
Blood. 84(11)
In 1945, Thomas Cooley described the first cases of X-linked sideroblastic anemia (XLSA) in two brothers from a large family in which the inheritance of the disease was documented through six generations. Almost 40 years later the enzymatic defect in
Publikováno v:
Blood. 84(6)
A subset of sickle cells have an increased density at the reticulocyte stage of development, indicating that they are either abnormally dense upon release from the bone marrow or become dense quickly in the circulation. These cells are of interest be
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 34(4)
In order to determine if a relationship exists between rib infarction and the acute chest syndrome (ACS) in sickle cell disease patients, bone scans were reviewed in 55 episodes in 38 patients with pain of suspected osseous origin. A bone scan was po
Publikováno v:
The Journal of laboratory and clinical medicine. 118(4)
Yield stress is a sensitive index of blood fluidity at low shear stress. Using a method that measured the stress required to cause motion of a thin sedimenting layer of red cells, we found significant elevations of yield stress in patients with homoz
Publikováno v:
Hemoglobin. 15(5)
We have determined the structural abnormality of a putative Hb E detected in an African-American family with no apparent Asian ancestry. The tryptic peptide map performed by high performance liquid chromatography showed that the electrophoretic varia