Zobrazeno 1 - 10 of 10 pro vyhledávání: '"D L, Mager"'
1
Keeping active endogenous retroviral-like elements in check: the epigenetic perspective
Autor: I A, Maksakova, D L, Mager, D, Reiss
Publikováno v: Cellular and molecular life sciences : CMLS. 65(21)
Endogenous retrovirus-like elements, or ERVs, are an abundant component of all eukaryotic genomes. Their transcriptional and retrotranspositional activities have great potential for deleterious effects on gene expression. Consequences of such activit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c803015343291d55f86631b0849eca2e
https://pubmed.ncbi.nlm.nih.gov/18818875
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2
Ly49 and CD94/NKG2: developmentally regulated expression and evolution
Autor: F, Takei, K L, McQueen, M, Maeda, B T, Wilhelm, S, Lohwasser, R H, Lian, D L, Mager
Publikováno v: Immunological reviews. 181
Murine natural killer (NK) cells express two families of MHC class I-specific receptors, namely the Ly49 family and CD94/NKG2 heterodimers. Stochastic co-expression of these receptors generates diverse receptor repertoires in adult NK-cell population
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f8d1375aefe00a0f28008b290dfd92e9
https://pubmed.ncbi.nlm.nih.gov/11513155
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3
Evolution of natural killer cell receptors: coexistence of functional Ly49 and KIR genes in baboons
Autor: D L, Mager, K L, McQueen, V, Wee, J D, Freeman
Publikováno v: Current biology : CB. 11(8)
Natural killer (NK) cells represent an important first line of defense against viruses and malignancy [1]. NK cells express a variety of inhibitory and activating receptors that interact with classical major histocompatibility complex (MHC) class I m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7680e53fd7953a82715dcb61ad7974f5
https://pubmed.ncbi.nlm.nih.gov/11369209
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4
The genomic organization of the mouse CD94 C-type lectin gene
Autor: S, Lohwasser, B, Wilhelm, D L, Mager, F, Takei
Publikováno v: European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics. 27(3)
The mouse natural killer (NK) gene complex is located on chromosome 6 and contains a number of genes encoding C-type lectin receptors which have been found to regulate NK cell function. Among these are CD94 and four NKG2 genes. Like its human counter
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9b6f16b51888bf4698343373421e2110
https://pubmed.ncbi.nlm.nih.gov/10940084
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5
Cloning of murine NKG2A, B and C: second family of C-type lectin receptors on murine NK cells
Autor: S, Lohwasser, P, Hande, D L, Mager, F, Takei
Publikováno v: European journal of immunology. 29(3)
Multiple NK cell receptors for MHC class I have been identified. They include killer inhibitory receptors and CD94/NKG2 heterodimers in humans and the Ly49 family in mice. Here we report the cloning of murine NKG2A, B and C. The deduced amino acid se
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cf18561e5464922be4598aea5123c57a
https://pubmed.ncbi.nlm.nih.gov/10092077
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6
Role of conserved glycosylation site unique to murine class I MHC in recognition by Ly-49 NK cell receptor
Autor: R H, Lian, J D, Freeman, D L, Mager, F, Takei
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 161(5)
The recognition of class I MHC molecules on target cells by the Ly-49 family of receptors regulates NK cytotoxicity. Previous studies have suggested that carbohydrates are involved in the recognition of class I MHC by Ly-49, although their precise ro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5b1a1f224076ee115c97fef6bc361356
https://pubmed.ncbi.nlm.nih.gov/9725224
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8
A retrovirus-like element occurs between the 3' breakpoints of two large deletions in the human beta-globin gene cluster
Autor: D L, Mager, P S, Henthorn
Publikováno v: Progress in clinical and biological research. 191
We have identified a novel repetitive family in human DNA. One member of this family is found downstream of the beta-globin gene cluster between the 3' breakpoints of the deletions associated with Chinese G gamma + (A gamma delta beta)O thalassemia a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::91d6c4a63fadf0c47e9a3e5d205881ca
https://pubmed.ncbi.nlm.nih.gov/2413485
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9
A Chinese G gamma + (A gamma delta beta)zero thalassemia deletion: comparison to other deletions in the human beta-globin gene cluster and sequence analysis of the breakpoints
Autor: D L, Mager, P S, Henthorn, O, Smithies
Publikováno v: Nucleic acids research. 13(18)
A clone was isolated that contains the deletion junction region from an individual with a deletion associated with Chinese G gamma + (A gamma delta beta)zero thalassemia. A clone containing the normal DNA corresponding to the 3' breakpoint of this de
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::66c305c28545b5f15907fa95b08d04f1
https://pubmed.ncbi.nlm.nih.gov/2997715
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10
Homologous recombination between the LTRs of a human retrovirus-like element causes a 5-kb deletion in two siblings
Autor: D L, Mager, N L, Goodchild
Publikováno v: American journal of human genetics. 45(6)
The RTVL-H family of human endogenous retrovirus-like elements consists of approximately 1,000 intact members and of a similar number of solitary long terminal repeats (LTRs). In this study, the genetic heterogeneity of these elements has been invest
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::671010bba2ccc75dd5dece3eb8094f10
https://pubmed.ncbi.nlm.nih.gov/2573998
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