Zobrazeno 1 - 10
of 38
pro vyhledávání: '"D L, Laskin"'
Publikováno v:
Advances in experimental medicine and biology. 500
One of the hallmarks of the inflammatory response associated with tissue injury is the accumulation of macrophages at sites of damage. These cell types release proinflammatory cytokines and cytotoxic mediators to destroy invading pathogens and initia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b49b0037d4089ea9d2bdffb40b47b8ef
https://pubmed.ncbi.nlm.nih.gov/11764933
https://pubmed.ncbi.nlm.nih.gov/11764933
Publikováno v:
Journal of leukocyte biology. 70(2)
Although initially considered merely "scavenger cells" that participate in immunologic responses only after B and T lymphocytes have performed their biological tasks, more recent evidence suggests that macrophages play a key role in host defense as w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d5ff430b10283e29ed03d4db20219338
https://pubmed.ncbi.nlm.nih.gov/11493607
https://pubmed.ncbi.nlm.nih.gov/11493607
Autor:
B, Billack, D E, Heck, D M, Porterfield, R P, Malchow, P J, Smith, C R, Gardner, D L, Laskin, J D, Laskin
Publikováno v:
Biochemical pharmacology. 61(12)
Pharmacological modulation of nitric oxide synthase activity has been achieved using structural analogs of arginine. In the present studies, we demonstrated that the minimal amidine structure required for enzymatic inhibition is formamidine. We found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c678f7acc5755c91f80696efcb6746a7
https://pubmed.ncbi.nlm.nih.gov/11377388
https://pubmed.ncbi.nlm.nih.gov/11377388
Publikováno v:
Journal of leukocyte biology. 68(5)
Chronic ethanol consumption is associated with increased incidence of hepatic and pulmonary infections. To determine if this is correlated with altered macrophage activity, we analyzed the functional properties of cells isolated sequentially from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9dc9cdc983814c7644a7e1cf6e0ba2c2
https://pubmed.ncbi.nlm.nih.gov/11073098
https://pubmed.ncbi.nlm.nih.gov/11073098
Publikováno v:
Journal of biomedical materials research. 50(3)
Using a rodent air pouch, the inflammatory responses to biomaterials with distinct physical properties and chemical compositions were compared. The polymers examined were expanded poly(tetrafluoroethylene) (ePTFE), silicone, low-density polyethylene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::961811f37d7b986efcd5ac909d819a91
https://pubmed.ncbi.nlm.nih.gov/10737878
https://pubmed.ncbi.nlm.nih.gov/10737878
Publikováno v:
Pharmacologytherapeutics. 84(3)
Nitric oxide is produced by many cell types in the lung and plays an important physiologic role in the regulation of pulmonary vasomotor tone by several known mechanisms. Nitric oxide stimulates soluble guanylyl cyclase, resulting in increased levels
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f6c7a5d5d6b9a35a16e404ba48575160
https://pubmed.ncbi.nlm.nih.gov/10665837
https://pubmed.ncbi.nlm.nih.gov/10665837
Publikováno v:
Journal of inflammation. 48(2)
The nature and the extent of the damage that occurs in the lung following exposure to pulmonary irritants vary with the pathogenic agent. In the present studies we determined if this was due to unique functional responses of adherent vascular neutrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7df9120766b2e20ffd77ac046bd51c91
https://pubmed.ncbi.nlm.nih.gov/9656142
https://pubmed.ncbi.nlm.nih.gov/9656142
Publikováno v:
Advances in experimental medicine and biology. 387
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ffa0480be6bbcfac4dbe3e0a7710551
https://pubmed.ncbi.nlm.nih.gov/8794206
https://pubmed.ncbi.nlm.nih.gov/8794206
Autor:
D L, Laskin, M, Rodriguez del Valle, D E, Heck, S M, Hwang, S T, Ohnishi, S K, Durham, N L, Goller, J D, Laskin
Publikováno v:
Hepatology (Baltimore, Md.). 22(1)
In the present studies, we analyzed the effects of acute endotoxemia on hepatocyte nitric oxide production and functional activity. Treatment of rats with 5 mg/kg of lipopolysaccharide (LPS), which induces acute endotoxemia, caused an increase in nit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2698fe1f5d832d5f7af582772d01843d
https://pubmed.ncbi.nlm.nih.gov/7541386
https://pubmed.ncbi.nlm.nih.gov/7541386
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 273(2)
Topical application of beta-naphthoflavone to CD-1 mice induced an 87-fold increase in epidermal 7-ethoxyresorufin O-dealkylation activity per cell and a many-fold increase in epidermal cytochrome P-4501A1 (CYP1A1) concentration. Flow cytometric anal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c55d33f084cf92d28bda0b12953e3ec8
https://pubmed.ncbi.nlm.nih.gov/7752102
https://pubmed.ncbi.nlm.nih.gov/7752102