Zobrazeno 1 - 10
of 13
pro vyhledávání: '"D L, Haviland"'
Autor:
X Wang, D T Fleischer, W T Whitehead, D L Haviland, S I Rosenfeld, J P Leddy, R Snyderman, R A Wetsel
Publikováno v:
The Journal of Immunology. 154:5464-5471
Hereditary C5 deficiency has been reported in several families of different ethnic backgrounds and from different geographic regions, but the molecular genetic defect causing C5 deficiency has not been delineated in any of them. To examine the molecu
Autor:
D L Haviland, R L McCoy, W T Whitehead, H Akama, E P Molmenti, A Brown, J C Haviland, W C Parks, D H Perlmutter, R A Wetsel
Publikováno v:
The Journal of Immunology. 154:1861-1869
The small-complement C5 activation fragment, C5a, is a potent phlogistic molecule that, on binding to the C5a Receptor (C5aR), mediates contraction of smooth muscle, enhances vascular permeability, and promotes leukocyte functions such as directed ch
Publikováno v:
Journal of immunological methods. 390(1-2)
Monocytes have been used to assess immune dysfunction and disease. While mouse models are a useful longitudinal analog, few researchers have assessed changes in mouse monocytes. The purpose of this study was to provide recommendations for the sample
Publikováno v:
The Journal of Immunology. 146:362-368
Two truncated human C5 clones, pHC5A and pHC5B, were isolated from an adult human liver cDNA library, and contained inserts of 2930 and 2181 bp, respectively. Both clones were polyadenylated and encoded the 5'-end of the C5 pro-molecule, thereby comp
Autor:
X, Wang, D T, Fleischer, W T, Whitehead, D L, Haviland, S I, Rosenfeld, J P, Leddy, R, Snyderman, R A, Wetsel
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 154(10)
Hereditary C5 deficiency has been reported in several families of different ethnic backgrounds and from different geographic regions, but the molecular genetic defect causing C5 deficiency has not been delineated in any of them. To examine the molecu
Publikováno v:
The Journal of biological chemistry. 266(28)
Human C5 cDNA fragments were used to identify five overlapping cosmid clones that spanned the entire C5 gene. Partial sequencing and Southern analysis of the clones were performed to identify intron/exon boundaries and to map intron size. The human C
Publikováno v:
The Journal of biological chemistry. 266(18)
To understand fifth complement component (C5) gene regulation, splicing, and C5 protein deficiency at the molecular level, the organization of the murine C5 gene was determined. The C5 structural gene is present as a single copy in the mouse genome a
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 146(1)
Two truncated human C5 clones, pHC5A and pHC5B, were isolated from an adult human liver cDNA library, and contained inserts of 2930 and 2181 bp, respectively. Both clones were polyadenylated and encoded the 5'-end of the C5 pro-molecule, thereby comp
Publikováno v:
The Journal of biological chemistry. 265(5)
To ascertain the molecular mechanism that causes murine C5 deficiency, genomic and cDNA libraries were constructed from mouse liver DNA and mRNA employing the congenic strains B10.D2/nSnJ and B10.D2/oSnJ that are sufficient and deficient for C5, resp
Publikováno v:
The Journal of Immunology. 135:4034-4043
Several cloned lines of IL 2-dependent human T cells derived from alloantigen, mitogen, or IL 2-stimulated peripheral blood lymphocytes were examined for their surface marker expression, cytolytic activity in a 51Cr-release assay, and capacity to rel