Zobrazeno 1 - 5
of 5
pro vyhledávání: '"D L, Doubek"'
Autor:
G R, Pettit, R, Tan, N, Melody, J M, Kielty, R K, Pettit, D L, Herald, B E, Tucker, L P, Mallavia, D L, Doubek, J M, Schmidt
Publikováno v:
Bioorganicmedicinal chemistry. 7(5)
A Montana soil actinomycete, Streptomyces anulatus, produced (1 x 10(-2)% yield) a new cancer cell growth inhibitory cyclooctadepsipeptide named montanastatin (1) accompanied by the potent anticancer antibiotic valinomycin (2) in very high (5.1%) yie
Autor:
G R, Pettit, J P, Xu, F, Hogan, M D, Williams, D L, Doubek, J M, Schmidt, R L, Cerny, M R, Boyd
Publikováno v:
Journal of natural products. 60(8)
An investigation of the sea hare Dolabella auricularia from Papua New Guinea has led to discovery of the new cyclodepsipeptide dolastatin 16 (3) containing two new amino acid units designated dolamethylleuine (Dml) and dolaphenvaline (Dpv). The struc
Publikováno v:
Anti-cancer drug design. 10(3)
Owing to its sparingly soluble properties, the potential anticancer drug pancratistatin (1) resisted conventional drug formulation procedures and the synthesis of a water-soluble prodrug became necessary. That important objective for further pre-clin
Autor:
G R, Pettit, C L, Herald, M R, Boyd, J E, Leet, C, Dufresne, D L, Doubek, J M, Schmidt, R L, Cerny, J N, Hooper, K C, Rützler
Publikováno v:
Journal of medicinal chemistry. 34(11)
Autor:
G. R. PETTIT, M. INOUE, Y. KAMANO, D. L. HERALD, C. ARM, C. DUFRESNE, N. D. CHRISTIE, J. M. SCHMIDT, D. L. DOUBEK, T. S. KRUPA
Publikováno v:
ChemInform. 19