Zobrazeno 1 - 10
of 14
pro vyhledávání: '"D L, Crowe"'
Autor:
D. L. Crowe
Publikováno v:
Current Cancer Drug Targets. 2:77-86
For many years, the vitamin A metabolite retinoic acid (RA) has been known to have profound effects on development, cellular proliferation and differentiation, and tumor growth and invasion. The wide-ranging effects of RA on cellular proliferation an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f314c4fd5519265e78ad81161ba40a6a
https://doi.org/10.2174/1568009023333935
https://doi.org/10.2174/1568009023333935
Publikováno v:
Cell Biology and Toxicology. 9:385-403
The use of normal adult liver hepatocytes in cell culture for biochemical, toxicological and pharmacological studies has been greatly limited owing to the loss of replicative capacity and differentiated liver function. This is contrary to the ability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6f5d026f349a58582e2eb5a46384da
https://doi.org/10.1007/bf00754467
https://doi.org/10.1007/bf00754467
Publikováno v:
Histology and histopathology. 17(3)
Squamous cell carcinoma of the head and neck region (HNSCC) is the sixth most frequent cancer worldwide, comprising almost 50% of all malignancies in some developing nations. In the United States, 30,000 new cases and 8,000 deaths are reported each y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::026cd776cbe185b2d7f8218413a501aa
https://pubmed.ncbi.nlm.nih.gov/12168802
https://pubmed.ncbi.nlm.nih.gov/12168802
Autor:
D L, Crowe, B, Shemirani
Publikováno v:
Anticancer research. 20(5A)
The mitogen activated protein kinase (MAPK) pathway is a paradigm for regulation of growth factor signaling and cellular proliferation. The MAPK pathway is a major target for signaling by growth factor receptor kinases. The MAPK pathway consists of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f3efc133cb0c465ad85a07f536ad13cf
https://pubmed.ncbi.nlm.nih.gov/11062705
https://pubmed.ncbi.nlm.nih.gov/11062705
Autor:
D K, Tsang, D L, Crowe
Publikováno v:
International journal of oncology. 15(3)
Growth factor receptors of the tyrosine kinase family regulate proliferation and migration of a variety of cell types. Binding of cognate ligands to these receptors induces multiple cellular responses, including cell cycle progression and motility in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::70a749c6fbf77532322da30716cc7fda
https://pubmed.ncbi.nlm.nih.gov/10427134
https://pubmed.ncbi.nlm.nih.gov/10427134
Autor:
D L, Crowe, C F, Shuler
Publikováno v:
Histology and histopathology. 14(2)
The ability of malignant tumor cells to invade normal surrounding tissue contributes in large part to the significant morbidity and mortality of these cancers. The process of invasion involves adherence of the tumor cells to the extracellular matrix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3a20a6ffa8d4607d3533c24ec67d5127
https://pubmed.ncbi.nlm.nih.gov/10212827
https://pubmed.ncbi.nlm.nih.gov/10212827
Publikováno v:
Anticancer research. 18(5A)
Deregulation of cell death pathways is an important feature of tumorigenesis. Fas, a member of the tumor necrosis factor receptor superfamily, is a transmembrane protein that can transduce cell death signals via a proteolytic cascade upon crosslinkin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f7d3f80878ac742ee48e28f162e3a60e
https://pubmed.ncbi.nlm.nih.gov/9858879
https://pubmed.ncbi.nlm.nih.gov/9858879
Publikováno v:
The International journal of developmental biology. 42(6)
The disappearance of medial edge epithelium (MEE) is a critical event for palate fusion. TGF-beta3 is one factor participating in the regulation of this process. To investigate the nature of ligand-receptor interactions in vivo between TGF-beta3 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a46b2b44ed74d69a8892d2e42463e7ba
https://pubmed.ncbi.nlm.nih.gov/9727838
https://pubmed.ncbi.nlm.nih.gov/9727838
Autor:
D L, Crowe, C F, Shuler
Publikováno v:
Cell growthdifferentiation : the molecular biology journal of the American Association for Cancer Research. 9(8)
The chemotherapeutic agent and vitamin A metabolite retinoic acid (RA) has been used to treat many tumor types. The effects of RA are mediated by a family of ligand-dependent transcription factors, the RA receptors and the retinoid X receptors (RXR).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::62cd3391794ee5853ffa07d6c6fa10a9
https://pubmed.ncbi.nlm.nih.gov/9716179
https://pubmed.ncbi.nlm.nih.gov/9716179
Publikováno v:
Molecular carcinogenesis. 22(1)
Mutations in receptors for the vitamin A metabolite retinoic acid (RAR) that repress retinoic acid (RA)-responsive gene expression have been identified and characterized. We previously reported an absence of target gene response to RA in all but one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9a69c91f6281e15de78350089f55d2e8
https://pubmed.ncbi.nlm.nih.gov/9609098
https://pubmed.ncbi.nlm.nih.gov/9609098