Zobrazeno 1 - 10
of 3 310
pro vyhledávání: '"D Kramer"'
Multiple bloodmeals enhance dissemination of arboviruses in three medically relevant mosquito genera
Autor:
Zannatul Ferdous, Constentin Dieme, Hannah Sproch, Laura D. Kramer, Alexander T. Ciota, Doug E. Brackney, Philip M. Armstrong
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-7 (2024)
Abstract Background Mosquitoes in nature may acquire multiple bloodmeals (BMs) over the course of their lifetime; however, incorporation of frequent feeding behavior in laboratory vector competence studies is rarely done. We have previously shown tha
Externí odkaz:
https://doaj.org/article/e81ed97f895c42da973395d1f126c857
Autor:
S. Omme, J. Wang, M. Sifuna, J. Rodriguez, N. R. Owusu, M. Goli, P. Jiang, P. Waziha, J. Nwaiwu, C. L. Brelsfoard, A. Vigneron, A. T. Ciota, L. D. Kramer, Y. Mechref, M. G. Onyangos
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The microbial communities residing in the mosquito midgut play a key role in determining the outcome of mosquito pathogen infection. Elizabethkingia anophelis, originally isolated from the midgut of Anopheles gambiae possess a broad-spectrum
Externí odkaz:
https://doaj.org/article/c3221e68a86e4ec198e5e25e3a9082ed
Autor:
Maria G. Onyango, Anne F. Payne, Jessica Stout, Constentin Dieme, Lili Kuo, Laura D. Kramer, Alexander T. Ciota
Publikováno v:
Parasites & Vectors, Vol 17, Iss 1, Pp 1-10 (2024)
Abstract Background Past findings demonstrate that arthropods can egest midgut microbiota into the host skin leading to dual colonization of the vertebrate host with pathogens and saliva microbiome. A knowledge gap exists on how the saliva microbiome
Externí odkaz:
https://doaj.org/article/64afcdc8695c4d3bbec1ee974ebd55c0
Autor:
Stephanie L. Tzetzo, Elliot D. Kramer, Hemn Mohammadpour, Minhyung Kim, Spencer R. Rosario, Han Yu, Melissa R. Dolan, Chetan C. Oturkar, Brian G. Morreale, Paul N. Bogner, Aimee B. Stablewski, Fernando J. Benavides, Craig M. Brackett, John M.L. Ebos, Gokul M. Das, Mateusz Opyrchal, Michael J. Nemeth, Sharon S. Evans, Scott I. Abrams
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109187- (2024)
Summary: Tissue-resident macrophages (TRMs) are abundant immune cells within pre-metastatic sites, yet their functional contributions to metastasis remain incompletely understood. Here, we show that alveolar macrophages (AMs), the main TRMs of the lu
Externí odkaz:
https://doaj.org/article/b0dead588580421280f878bb0ac7259a
Autor:
Victor T. Merit, MD, Mathilde E. Kirk, BSc Medicine, Jacob G. Schultz, MD, PhD, Jacob V. Hansen, MD, PhD-fellow, Mads D. Lyhne, MD, PhD, Anders D. Kramer, MD, PhD-fellow, Christina C. E. Pedersen, Radiographer, Lina Karout, MD, Mannudeep K. Kalra, MD, Asger Andersen, MD, PhD, Jens Erik Nielsen-Kudsk, MD, DMSc
Publikováno v:
Critical Care Explorations, Vol 6, Iss 2, p e1040 (2024)
OBJECTIVES:. To investigate the contribution of mechanical obstruction and pulmonary vasoconstriction to pulmonary vascular resistance (PVR) in acute pulmonary embolism (PE) in pigs. DESIGN:. Controlled, animal study. SETTING:. Tertiary university ho
Externí odkaz:
https://doaj.org/article/21be07e77b5d4100b61d8fb655429a29
Autor:
Rachel E. Lange, Alan P. Dupuis II, Melissa A. Prusinski, Joseph G. Maffei, Cheri A. Koetzner, Kiet Ngo, Bryon Backenson, JoAnne Oliver, Chantal B.F. Vogels, Nathan D. Grubaugh, Laura D. Kramer, Alexander T. Ciota
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 1 (2023)
ABSTRACTPowassan virus (POWV, family Flaviviridae) is a reemerging tick-borne virus endemic in North America and Russia. In 1997, a POWV-like agent was isolated from Ixodes scapularis in New England and determined to be genetically distinct from the
Externí odkaz:
https://doaj.org/article/b0e3a4a29e9f4e4bb242376bbeefd55a
Autor:
Karen M. Holcomb, Sarabeth Mathis, J. Erin Staples, Marc Fischer, Christopher M. Barker, Charles B. Beard, Randall J. Nett, Alexander C. Keyel, Matteo Marcantonio, Marissa L. Childs, Morgan E. Gorris, Ilia Rochlin, Marco Hamins-Puértolas, Evan L. Ray, Johnny A. Uelmen, Nicholas DeFelice, Andrew S. Freedman, Brandon D. Hollingsworth, Praachi Das, Dave Osthus, John M. Humphreys, Nicole Nova, Erin A. Mordecai, Lee W. Cohnstaedt, Devin Kirk, Laura D. Kramer, Mallory J. Harris, Morgan P. Kain, Emily M. X. Reed, Michael A. Johansson
Publikováno v:
Parasites & Vectors, Vol 16, Iss 1, Pp 1-13 (2023)
Abstract Background West Nile virus (WNV) is the leading cause of mosquito-borne illness in the continental USA. WNV occurrence has high spatiotemporal variation, and current approaches to targeted control of the virus are limited, making forecasting
Externí odkaz:
https://doaj.org/article/2ee21ea30b4a49b5a774c7a9b548f0c6
Autor:
Alan P. Dupuis, Melissa A. Prusinski, Collin O’Connor, Joseph G. Maffei, Cheri A. Koetzner, Tela E. Zembsch, Steven D. Zink, Alexis L. White, Michael P. Santoriello, Christopher L. Romano, Guang Xu, Fumiko Ribbe, Scott R. Campbell, Stephen M. Rich, P. Bryon Backenson, Laura D. Kramer, Alexander T. Ciota
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 1, Pp 145-148 (2023)
In July 2019, Bourbon virus RNA was detected in an Amblyomma americanum tick removed from a resident of Long Island, New York, USA. Tick infection and white-tailed deer (Odocoileus virginianus) serosurvey results demonstrate active transmission in Ne
Externí odkaz:
https://doaj.org/article/f6de28f953ae45509cebf46e87c7777b
Autor:
Eric McDade, Jeffrey L. Cummings, Shobha Dhadda, Chad J. Swanson, Larisa Reyderman, Michio Kanekiyo, Akihiko Koyama, Michael Irizarry, Lynn D. Kramer, Randall J. Bateman
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-17 (2022)
Abstract Background Lecanemab, a humanized IgG1 monoclonal antibody that targets soluble aggregated Aβ species (protofibrils), has demonstrated robust brain fibrillar amyloid reduction and slowing of clinical decline in early AD. The objective of th
Externí odkaz:
https://doaj.org/article/a6d9281674a5413f8b67e7a74816d854
Autor:
Shobha Dhadda, Michio Kanekiyo, David Li, Chad J. Swanson, Michael Irizarry, Scott Berry, Lynn D. Kramer, Donald A. Berry
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-9 (2022)
Abstract Background Lecanemab (BAN2401) is a humanized IgG1 monoclonal antibody that preferentially targets soluble aggregated Aβ species (protofibrils) with activity at insoluble fibrils and slowed clinical decline in an 18-month phase 2 proof-of-c
Externí odkaz:
https://doaj.org/article/4ce48fe8ab7742dd95eb4cc183c3ed7b