Zobrazeno 1 - 10
of 8 488
pro vyhledávání: '"D Klein"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Contending with discrimination can yield a cascade of negative psychological and physiological outcomes which adversely affect health. How individuals manage their emotions in response to discrimination can influence the extent of these nega
Externí odkaz:
https://doaj.org/article/94125d08847c4c9f97d8e213209775b5
Autor:
Zachary T. Calamari, Andrew Song, Emily Cohen, Muspika Akter, Rishi Das Roy, Outi Hallikas, Mona M. Christensen, Pengyang Li, Pauline Marangoni, Jukka Jernvall, Ophir D. Klein
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Background Continuously growing teeth are an important innovation in mammalian evolution, yet genetic regulation of continuous growth by stem cells remains incompletely understood. Dental stem cells responsible for tooth crown growth are los
Externí odkaz:
https://doaj.org/article/7016d160d0634ccd86d7e97904abdff2
Autor:
Gisela Altés, Anna Olomí, Aida Perramon-Güell, Sara Hernández, Anna Casanovas, Aurora Pérez, Juan Miguel Díaz-Tocados, José Manuel Valdivielso, Cristina Megino, Raúl Navaridas, Xavier Matias-Guiu, Ophir D. Klein, Joaquim Egea, Xavi Dolcet, Andrée Yeramian, Mario Encinas
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Genes of the Sprouty family (Spry1-4) are feedback inhibitors of receptor tyrosine kinases, especially of Ret and the FGF receptors. As such, they play distinct and overlapping roles in embryo morphogenesis and are considered to be tumor sup
Externí odkaz:
https://doaj.org/article/c35f82b053404988a6db6232e37d7598
Autor:
K Saravanan, N Schaeren-Wiemers, D Klein, R Sandhoff, A Schwarz, A Yaghootfam, V Gieselmann, S Franken
Publikováno v:
Neurobiology of Disease, Vol 16, Iss 2, Pp 396-406 (2004)
Metachromatic leukodystrophy (MLD) is a lysosomal lipid storage disease caused by arylsulfatase A deficiency. In MLD patients the sphingolipid sulfatide increasingly accumulates leading to progressive demyelination. We have analysed arylsulfatase A-d
Externí odkaz:
https://doaj.org/article/fddcd4ae7a9a45d596579510d1dcb123
Autor:
Alison D. Klein, Michael Overholtzer
Publikováno v:
Autophagy Reports, Vol 3, Iss 1 (2024)
Much is still unknown about microautophagy and its regulators. In our recent paper, one such regulator of microautophagy, the lipid kinase PIKfyve, is described. Previously it was found that treating cells with agents like lysomotropic drugs or proto
Externí odkaz:
https://doaj.org/article/745bccee7e2247d3be4ac9188a3449b3
Autor:
Wei Du, Adya Verma, Qianlin Ye, Wen Du, Sandy Lin, Atsushi Yamanaka, Ophir D Klein, Jimmy K Hu
Publikováno v:
PLoS Genetics, Vol 20, Iss 6, p e1011326 (2024)
The development of ectodermal organs begins with the formation of a stratified epithelial placode that progressively invaginates into the underlying mesenchyme as the organ takes its shape. Signaling by secreted molecules is critical for epithelial m
Externí odkaz:
https://doaj.org/article/d38b9ae49d034e0a9df54926422d4e30
Autor:
Saeka Rahman, Md Motiur Rahman, Miad Faezipour, Mo Rastgaar, Elika Ridelman, Justin D. Klein, Beth A. Angst, Christina M. Shanti
Publikováno v:
IEEE Access, Vol 12, Pp 147249-147268 (2024)
Burn injuries present a substantial global public health challenge. The conventional approach, relying on visual inspection to compute total body surface area (TBSA) for assessing burn severity, encounters the inherent limitations of proper estimatio
Externí odkaz:
https://doaj.org/article/92929069f6354d10999fee841f6bb460
Autor:
Hyun-Yi Kim, Victoria Cooley, Eun-Jung Kim, Shujin Li, Jong-Min Lee, Dina Sheyfer, Wenjun Liu, Ophir D. Klein, Derk Joester, Han-Sung Jung
Publikováno v:
International Journal of Oral Science, Vol 15, Iss 1, Pp 1-15 (2023)
Abstract Ameloblasts are specialized cells derived from the dental epithelium that produce enamel, a hierarchically structured tissue comprised of highly elongated hydroxylapatite (OHAp) crystallites. The unique function of the epithelial cells synth
Externí odkaz:
https://doaj.org/article/69f72bb2aa6741ab8928e95c641fc3f5
Autor:
A. Schneibel, M. Gähler, M. Halbgewachs, R. Berger, J. Brauchle, M. Geßner, V. Gstaiger, D. Hein, C. Henry, N. Merkle, D. Klein
Publikováno v:
The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, Vol XLVIII-M-1-2023, Pp 579-586 (2023)
In the early morning hours on Tuesday, February 6, 2023, the southern part of Türkiye was struck by two large and several smaller earthquakes, causing destruction and casualties over a remarkably large area. In such cases, quick response and well-in
Externí odkaz:
https://doaj.org/article/5320abc726ad49c1b57d19f3d7190d09
Autor:
Macarena Las Heras, Benjamín Szenfeld, Rami A. Ballout, Emanuele Buratti, Silvana Zanlungo, Andrea Dardis, Andrés D. Klein
Publikováno v:
npj Genomic Medicine, Vol 8, Iss 1, Pp 1-13 (2023)
Abstract Niemann-Pick type C (NPC) disease is a lysosomal storage disease (LSD) characterized by the buildup of endo-lysosomal cholesterol and glycosphingolipids due to loss of function mutations in the NPC1 and NPC2 genes. NPC patients can present w
Externí odkaz:
https://doaj.org/article/32dbaaaf5f05426697b283303572d116