Zobrazeno 1 - 10
of 171
pro vyhledávání: '"D Kacy Cullen"'
Publikováno v:
Neural Regeneration Research, Vol 14, Iss 9, Pp 1481-1489 (2019)
Neuroinflammation is initiated as a result of traumatic brain injury and can exacerbate evolving tissue pathology. Immune cells respond to acute signals from damaged cells, initiate neuroinflammation, and drive the pathological consequences over time
Externí odkaz:
https://doaj.org/article/b68be16acd7b40009964c9d0e75ca969
Publikováno v:
Neural Regeneration Research, Vol 13, Iss 8, Pp 1327-1331 (2018)
New neurons are integrated into the circuitry of the olfactory bulb throughout the lifespan in the mammalian brain—including in humans. These new neurons are born in the subventricular zone and subsequently mature as they are guided over long dista
Externí odkaz:
https://doaj.org/article/c7695920aa90486298b4373c9c675490
Autor:
John D. Arena, Douglas H. Smith, Ramon Diaz Arrastia, D. Kacy Cullen, Rui Xiao, Jiaxin Fan, Danielle C. Harris, Cillian E. Lynch, Victoria E. Johnson
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-18 (2024)
Abstract Mild traumatic brain injury (mTBI) or concussion is a substantial health problem globally, with up to 15% of patients experiencing persisting symptoms that can significantly impact quality of life. Currently, the diagnosis of mTBI relies on
Externí odkaz:
https://doaj.org/article/865cf888570340b89bcbcc8ee4ccade3
Autor:
Flavia Vitale, Wendy Shen, Nicolette Driscoll, Justin C Burrell, Andrew G Richardson, Oladayo Adewole, Brendan Murphy, Akshay Ananthakrishnan, Hanju Oh, Theodore Wang, Timothy H Lucas, D Kacy Cullen, Mark G Allen, Brian Litt
Publikováno v:
PLoS ONE, Vol 13, Iss 11, p e0206137 (2018)
Intracranial electrodes are a vital component of implantable neurodevices, both for acute diagnostics and chronic treatment with open and closed-loop neuromodulation. Their performance is hampered by acute implantation trauma and chronic inflammation
Externí odkaz:
https://doaj.org/article/fbb42ab8eba748009a9be9eba21104d2
Publikováno v:
Neural Regeneration Research, Vol 10, Iss 5, Pp 679-685 (2015)
Neural tissue engineering is premised on the integration of engineered living tissue with the host nervous system to directly restore lost function or to augment regenerative capacity following nervous system injury or neurodegenerative disease. Disc
Externí odkaz:
https://doaj.org/article/10ed62e15a944aa5a447a4a897febc34
Autor:
Juan C. Sáez, Justin C. Burrell, Catherine M. Cahill, D. Kacy Cullen, Lakshmi A. Devi, Ryan J. Gilbert, Zachary A. Graham, Vadim J. Gurvich, Leif A. Havton, Ravi Iyengar, Rajesh Khanna, Edmund F. Palermo, Mustafa Siddiq, Carlos A. Toro, Walter Vasquez, Wei Zhao, Christopher P. Cardozo
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Over the past decade, boldine, a naturally occurring alkaloid found in several plant species including the Chilean Boldo tree, has garnered attention for its efficacy in rodent models of human disease. Some of the properties that have been attributed
Externí odkaz:
https://doaj.org/article/07edf235e1324a7b9a58860ef7edcbde
Publikováno v:
Skeletal Muscle, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Background Neurovascular cells have wide-ranging implications on skeletal muscle biology regulating myogenesis, maturation, and regeneration. Although several in vitro studies have investigated how motor neurons and endothelial cells interac
Externí odkaz:
https://doaj.org/article/1b18cddb03cb428da82c8470344d295f
Autor:
Erin M. Purvis, Andrés D. Garcia-Epelboim, Elizabeth N. Krizman, John C. O’Donnell, D. Kacy Cullen
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
In the brains of most adult mammals, neural precursor cells (NPCs) from the subventricular zone (SVZ) migrate through the rostral migratory stream (RMS) to replace olfactory bulb interneurons. Following brain injury, published studies have shown that
Externí odkaz:
https://doaj.org/article/2c988932fb9343e0be1849083d12b80b
Autor:
Alexandra V. Ulyanova, Christopher D. Adam, Carlo Cottone, Nikhil Maheshwari, Michael R. Grovola, Oceane E. Fruchet, Jami Alamar, Paul F. Koch, Victoria E. Johnson, D. Kacy Cullen, John A. Wolf
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Cognitive impairment is a common symptom following mild traumatic brain injury (mTBI or concussion) and can persist for years in some individuals. Hippocampal slice preparations following closed-head, rotational acceleration injury in swine
Externí odkaz:
https://doaj.org/article/2d33d06385b741a88a7d751abd977514
Autor:
Michael R. Grovola, D. Kacy Cullen
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 2019 (2024)
Traumatic brain injury (TBI) is a public health concern, with an estimated 42 million cases globally every year. The majority of TBIs are mild TBIs, also known as concussion, and result from the application of mechanical forces on the head. Most pati
Externí odkaz:
https://doaj.org/article/7b3c19cb82144111b2fab43343c75a45