Zobrazeno 1 - 10
of 22
pro vyhledávání: '"D K George"'
Publikováno v:
Journal of Gastroenterology and Hepatology. 14:745-749
There is increasing evidence that hepatotoxins, such as alcohol and the hepatitis viruses, act as co-factors in causing hepatic fibrosis and cirrhosis. For example, alcohol aggravates the hepatic damage produced by iron in hereditary haemochromatosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b0ed450f733d0e297c317fceec9b614
https://doi.org/10.1046/j.1440-1746.1999.01944.x
https://doi.org/10.1046/j.1440-1746.1999.01944.x
Autor:
L W Powell, D K George
Publikováno v:
Alimentary Pharmacology and Therapeutics. 11:631-639
Haemochromatosis was first recognized as a disease entity over a century ago and its hereditary nature recognized over 60 years ago. However it was only in late 1996 that the haemochromatosis gene was cloned and a single C282Y mutation confirmed as b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a61f6d7e6d1bfe2389901465c224019
https://doi.org/10.1046/j.1365-2036.1997.00197.x
https://doi.org/10.1046/j.1365-2036.1997.00197.x
Autor:
D. K. George, Darrell H. G. Crawford
Publikováno v:
Drug Safety. 15:79-85
Hepatotoxic reactions to antibacterials are rare, occurring with an estimated frequency of between 1 and 10 per 100,000 drug prescriptions for most antibacterials. Although many antibacterial-induced hepatotoxic reactions have a characteristic clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b18695c35df7855c79ab98f5b39763ca
https://doi.org/10.2165/00002018-199615010-00007
https://doi.org/10.2165/00002018-199615010-00007
Publikováno v:
Medical Journal of Australia. 164:348-351
Haemochromatosis is now known to be a common genetic disorder, with a carrier rate of about 1 in 10 in populations of Northern European origin. With early diagnosis and treatment, life expectancy is normal, yet it remains underdiagnosed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d5d8f682d11f27fe452352f3405c6a6
https://doi.org/10.5694/j.1326-5377.1996.tb122053.x
https://doi.org/10.5694/j.1326-5377.1996.tb122053.x
Autor:
R, Valdés Aguilar, A V, Stier, W, Liu, L S, Bilbro, D K, George, N, Bansal, L, Wu, J, Cerne, A G, Markelz, S, Oh, N P, Armitage
Publikováno v:
Physical review letters. 108(8)
We report the THz response of thin films of the topological insulator Bi2Se3. At low frequencies, transport is essentially thickness independent showing the dominant contribution of the surface electrons. Despite their extended exposure to ambient co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4d7c5af1f274c8f2022c6db28850c78
https://pubmed.ncbi.nlm.nih.gov/22463570
https://pubmed.ncbi.nlm.nih.gov/22463570
Publikováno v:
Heart (British Cardiac Society). 89(9)
Objectives: Excess iron stores have been postulated to enhance the risk of ischaemic heart disease. This study aims to determine whether the two major mutations of the haemochromatosis (HFE) gene (C282Y and H63D) are associated with ischaemic heart d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48cefd0767cd987e145d8e6622728e30
https://pubmed.ncbi.nlm.nih.gov/12923017
https://pubmed.ncbi.nlm.nih.gov/12923017
Autor:
Kim R. Bridle, Grant A. Ramm, Patrick Ward, D. K. George, Neal I. Walker, Graeme A. Macdonald, K Houglum, Darrell H. G. Crawford, J. L. Smith, Lawrie W. Powell
Publikováno v:
Journal of gastroenterology and hepatology. 16(6)
Background and Aims: Hepatic steatosis has been shown to be associated with lipid peroxidation and hepatic fibrosis in a variety of liver diseases including non-alcoholic fatty liver disease. However, the lobular distribution of lipid peroxidation as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6acd9acb17d84369db3631c61b3a0e6
https://pubmed.ncbi.nlm.nih.gov/11422610
https://pubmed.ncbi.nlm.nih.gov/11422610
Publikováno v:
Annals of internal medicine. 129(11)
If untreated, hemochromatosis can cause serious illness and early death, but the disease is still substantially under-diagnosed. The cornerstone of screening and case detection is the measurement of serum transferrin saturation and the serum ferritin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d5da903120dfbb239b0afeb0d9cf5a
https://pubmed.ncbi.nlm.nih.gov/10454956
https://pubmed.ncbi.nlm.nih.gov/10454956
Autor:
L. L. Cowley, Neal I. Walker, Grant A. Ramm, Darrell H. G. Crawford, Lawrie W. Powell, Linda M. Fletcher, D. K. George
Publikováno v:
Gut. 42(5)
Background—Altered matrix degradation contributes to fibrosis in some liver diseases but the role of matrix degradation in fibrogenesis associated with genetic haemochromatosis has not previously been addressed.Aims—To measure serum concentration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0372d15392d9427e8d1fdb26812b426
https://pubmed.ncbi.nlm.nih.gov/9659170
https://pubmed.ncbi.nlm.nih.gov/9659170